Skip to content
master
Switch branches/tags
Code

Latest commit

 

Git stats

Files

Permalink
Failed to load latest commit information.
Type
Name
Latest commit message
Commit time
R
 
 
 
 
 
 
 
 
man
 
 
 
 
src
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

install with bioconda European Galaxy server

DIAlignR

DIAlignR is an R package for retention time alignment of targeted mass spectrometric data, including DIA and SWATH-MS data. This tool works with MS2 chromatograms directly and uses dynamic programming for alignment of raw chromatographic traces. DIAlignR uses a hybrid approach of global (feature-based) and local (raw data-based) alignment to establish correspondence between peaks.

Travis build status

Documentation

For documentation please see our vignette.

Developing C++ code

cd DIAlignR
mkdir build && cd build
cmake -B. -H.. 
make clean && make && make test
make runTest3
cd ..

Documenting C++ code

sudo apt install doxygen doxygen-gui 
sudo apt install graphviz
cd DIAlignR
cd src
doxygen doc/Doxyfile

Installing Rcompression

devtools::install_github("omegahat/Rcompression")

Citation

If you use the provided algorithms or the package, please cite our paper:

Gupta S, Ahadi S, Zhou W, Röst H. "DIAlignR Provides Precise Retention Time Alignment Across Distant Runs in DIA and Targeted Proteomics." Mol Cell Proteomics. 2019 Apr;18(4):806-817. doi: https://doi.org/10.1074/mcp.TIR118.001132 Epub 2019 Jan 31.

CNPN 2018 Poster doi: https://doi.org/10.6084/m9.figshare.6200837.v1
HUPO 2018 Poster doi: https://doi.org/10.6084/m9.figshare.7121696.v2

About

This is a R package for alignment of DIA mass-spec data

Resources

Packages

No packages published