Bad Mutation Network
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README.md

Bad MutatioN (BMN)

Presentation

Identifying potential drugs for schwannomas.

Mutation Annotation

Annotating patient's mutations using ANNOVAR software.

Identifying genes dysregulated in schwannoma

Find the mutated genes that overlap with 1732 genes reported as up/down-regulated in a gene expression study by Nielsen et al. https://www.ncbi.nlm.nih.gov/pubmed/11965276.

Lit review

Found deleterious mutations in three genes. There are 2 drugs inhibiting the function of one of them, ITPR3.