diff --git a/.changeset/wild-rabbits-jump.md b/.changeset/wild-rabbits-jump.md
new file mode 100644
index 00000000000..1d6b19c286b
--- /dev/null
+++ b/.changeset/wild-rabbits-jump.md
@@ -0,0 +1,6 @@
+---
+'@tanstack/react-query': patch
+'@tanstack/query-core': patch
+---
+
+fix(suspense): skip calling combine when queries would suspend
diff --git a/packages/query-core/src/__tests__/queriesObserver.test.tsx b/packages/query-core/src/__tests__/queriesObserver.test.tsx
index 504f5b8379a..1adfa6195a6 100644
--- a/packages/query-core/src/__tests__/queriesObserver.test.tsx
+++ b/packages/query-core/src/__tests__/queriesObserver.test.tsx
@@ -473,6 +473,82 @@ describe('queriesObserver', () => {
     expect(newCombined.count).toBe(2)
   })
 
+  it('should skip combine notifications while suspense queries have no data', async () => {
+    const key = queryKey()
+    const combine = vi.fn((results: Array<QueryObserverResult>) =>
+      results.map((result) => result.data),
+    )
+    const query = {
+      queryKey: key,
+      queryFn: () => sleep(10).then(() => 'data'),
+      staleTime: Infinity,
+      suspense: true,
+    }
+
+    queryClient.setQueryData(key, 'data')
+
+    const observer = new QueriesObserver<Array<unknown>>(queryClient, [query], {
+      combine,
+    })
+
+    const [rawResult, getCombinedResult] = observer.getOptimisticResult(
+      [query],
+      combine,
+    )
+    expect(getCombinedResult(rawResult)).toEqual(['data'])
+    expect(combine).toHaveBeenCalledTimes(1)
+
+    const unsubscribe = observer.subscribe(() => undefined)
+
+    void queryClient.resetQueries({ queryKey: key })
+    expect(combine).toHaveBeenCalledTimes(1)
+
+    unsubscribe()
+  })
+
+  it('should skip combine notifications after suspense is enabled without structural changes', async () => {
+    const key = queryKey()
+    const combine = vi.fn((results: Array<QueryObserverResult>) =>
+      results.map((result) => result.data),
+    )
+    const query = {
+      queryKey: key,
+      queryFn: () => sleep(10).then(() => 'data'),
+      staleTime: Infinity,
+      suspense: false,
+    }
+
+    queryClient.setQueryData(key, 'data')
+
+    const observer = new QueriesObserver<Array<unknown>>(queryClient, [query], {
+      combine,
+    })
+
+    const [rawResult, getCombinedResult] = observer.getOptimisticResult(
+      [query],
+      combine,
+    )
+    expect(getCombinedResult(rawResult)).toEqual(['data'])
+    expect(combine).toHaveBeenCalledTimes(1)
+
+    const unsubscribe = observer.subscribe(() => undefined)
+
+    observer.setQueries(
+      [
+        {
+          ...query,
+          suspense: true,
+        },
+      ],
+      { combine },
+    )
+
+    void queryClient.resetQueries({ queryKey: key })
+    expect(combine).toHaveBeenCalledTimes(1)
+
+    unsubscribe()
+  })
+
   it('should handle queries being removed with stable combine reference', () => {
     const combine = vi.fn((results: Array<QueryObserverResult>) => ({
       count: results.length,
diff --git a/packages/query-core/src/queriesObserver.ts b/packages/query-core/src/queriesObserver.ts
index 67dd088f9ae..4fcf8e5d41e 100644
--- a/packages/query-core/src/queriesObserver.ts
+++ b/packages/query-core/src/queriesObserver.ts
@@ -249,6 +249,17 @@ export class QueriesObserver<
     return input as any
   }
 
+  #shouldSkipCombine(): boolean {
+    return (
+      this.#options?.combine !== undefined &&
+      this.#observers.some((observer, index) => {
+        return (
+          observer.options.suspense && this.#result[index]?.data === undefined
+        )
+      })
+    )
+  }
+
   #findMatchingObservers(
     queries: Array<QueryObserverOptions>,
   ): Array<QueryObserverMatch> {
@@ -294,11 +305,14 @@ export class QueriesObserver<
 
   #notify(): void {
     if (this.hasListeners()) {
-      const previousResult = this.#combinedResult
       const newTracked = this.#trackResult(this.#result, this.#observerMatches)
-      const newResult = this.#combineResult(newTracked, this.#options?.combine)
+      const shouldSkipCombine = this.#shouldSkipCombine()
+      const previousResult = this.#combinedResult
+      const newResult = shouldSkipCombine
+        ? previousResult
+        : this.#combineResult(newTracked, this.#options?.combine)
 
-      if (previousResult !== newResult) {
+      if (shouldSkipCombine || previousResult !== newResult) {
         notifyManager.batch(() => {
           this.listeners.forEach((listener) => {
             listener(this.#result)
diff --git a/packages/react-query/src/__tests__/useSuspenseQueries.test.tsx b/packages/react-query/src/__tests__/useSuspenseQueries.test.tsx
index d8838aee0da..6b5b327b6ee 100644
--- a/packages/react-query/src/__tests__/useSuspenseQueries.test.tsx
+++ b/packages/react-query/src/__tests__/useSuspenseQueries.test.tsx
@@ -274,6 +274,74 @@ describe('useSuspenseQueries', () => {
     expect(spy).toHaveBeenCalled()
   })
 
+  it('should not call combine while reset queries are pending again', async () => {
+    const consoleMock = vi
+      .spyOn(console, 'error')
+      .mockImplementation(() => undefined)
+    const key = queryKey()
+    let shouldError = false
+
+    function Page() {
+      const data = useSuspenseQueries({
+        queries: [
+          {
+            queryKey: key,
+            queryFn: () =>
+              sleep(10).then(() => {
+                if (shouldError) {
+                  throw new Error('Suspense Error Bingo')
+                }
+
+                return 'data'
+              }),
+            retry: false,
+          },
+        ],
+        combine: (result) => result.map((query) => query.data.toUpperCase()),
+      })
+
+      return (
+        <div>
+          <button
+            onClick={() => void queryClient.resetQueries({ queryKey: key })}
+          >
+            reset
+          </button>
+          <div>data: {data.join(',')}</div>
+        </div>
+      )
+    }
+
+    const rendered = renderWithClient(
+      queryClient,
+      <ErrorBoundary fallbackRender={() => <div>error boundary</div>}>
+        <React.Suspense fallback="loading">
+          <Page />
+        </React.Suspense>
+      </ErrorBoundary>,
+    )
+
+    expect(rendered.getByText('loading')).toBeInTheDocument()
+
+    await act(() => vi.advanceTimersByTimeAsync(10))
+    expect(rendered.getByText('data: DATA')).toBeInTheDocument()
+
+    shouldError = true
+
+    expect(() => {
+      fireEvent.click(rendered.getByText('reset'))
+    }).not.toThrow()
+
+    await act(() => vi.advanceTimersByTimeAsync(10))
+    expect(rendered.getByText('error boundary')).toBeInTheDocument()
+
+    expect(consoleMock.mock.calls[0]?.[1]).toStrictEqual(
+      new Error('Suspense Error Bingo'),
+    )
+
+    consoleMock.mockRestore()
+  })
+
   it('should handle duplicate query keys without infinite loops', async () => {
     const key = queryKey()
     const localDuration = 10