diff --git a/com.unity.render-pipelines.high-definition/CHANGELOG.md b/com.unity.render-pipelines.high-definition/CHANGELOG.md
index 147e010df59..0453efa69d3 100644
--- a/com.unity.render-pipelines.high-definition/CHANGELOG.md
+++ b/com.unity.render-pipelines.high-definition/CHANGELOG.md
@@ -109,6 +109,7 @@ and this project adheres to [Semantic Versioning](http://semver.org/spec/v2.0.0.
 - Fixed error when changing planar probe resolution.
 - Fixed the dependecy of FrameSettings (MSAA, ClearGBuffer, DepthPrepassWithDeferred) (case 1277620).
 - Fixed the usage of GUIEnable for volume components (case 1280018).
+- Fixed the diffusion profile becoming invalid when hitting the reset (case 1269462).
 
 ### Changed
 - Preparation pass for RTSSShadows to be supported by render graph.
diff --git a/com.unity.render-pipelines.high-definition/Runtime/Material/DiffusionProfile/DiffusionProfileSettings.cs b/com.unity.render-pipelines.high-definition/Runtime/Material/DiffusionProfile/DiffusionProfileSettings.cs
index 3ec6613de7e..3b60ac18899 100644
--- a/com.unity.render-pipelines.high-definition/Runtime/Material/DiffusionProfile/DiffusionProfileSettings.cs
+++ b/com.unity.render-pipelines.high-definition/Runtime/Material/DiffusionProfile/DiffusionProfileSettings.cs
@@ -1,4 +1,5 @@
 using System;
+using UnityEditor.Rendering.HighDefinition;
 
 namespace UnityEngine.Rendering.HighDefinition
 {
@@ -52,14 +53,19 @@ public enum TransmissionMode : uint
 
         // Here we need to have one parameter in the diffusion profile parameter because the deserialization call the default constructor
         public DiffusionProfile(bool dontUseDefaultConstructor)
+        {
+            ResetToDefault();
+        }
+
+        public void ResetToDefault()
         {
             scatteringDistance = Color.grey;
-            transmissionTint   = Color.white;
-            texturingMode      = TexturingMode.PreAndPostScatter;
-            transmissionMode   = TransmissionMode.ThinObject;
-            thicknessRemap     = new Vector2(0f, 5f);
-            worldScale         = 1f;
-            ior                = 1.4f; // Typical value for skin specular reflectance
+            transmissionTint = Color.white;
+            texturingMode = TexturingMode.PreAndPostScatter;
+            transmissionMode = TransmissionMode.ThinObject;
+            thicknessRemap = new Vector2(0f, 5f);
+            worldScale = 1f;
+            ior = 1.4f; // Typical value for skin specular reflectance
         }
 
         internal void Validate()
@@ -223,6 +229,15 @@ void OnEnable()
 #endif
         }
 
+        internal void Reset()
+        {
+            if (profile.hash == 0)
+            {
+                profile.ResetToDefault();
+                profile.hash = DiffusionProfileHashTable.GenerateUniqueHash(this);
+            }
+        }
+
         internal void UpdateCache()
         {
             worldScaleAndFilterRadiusAndThicknessRemap = new Vector4(profile.worldScale,
diff --git a/com.unity.render-pipelines.high-definition/Runtime/Utilities/DiffusionProfileHashTable.cs b/com.unity.render-pipelines.high-definition/Runtime/Utilities/DiffusionProfileHashTable.cs
index bb0fe224938..644b4252363 100644
--- a/com.unity.render-pipelines.high-definition/Runtime/Utilities/DiffusionProfileHashTable.cs
+++ b/com.unity.render-pipelines.high-definition/Runtime/Utilities/DiffusionProfileHashTable.cs
@@ -32,7 +32,7 @@ static uint GetDiffusionProfileHash(DiffusionProfileSettings asset)
             return (exponent << 23) | mantissa;
         }
 
-        static uint GenerateUniqueHash(DiffusionProfileSettings asset)
+        static internal uint GenerateUniqueHash(DiffusionProfileSettings asset)
         {
             uint hash = GetDiffusionProfileHash(asset);