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+# RES-Scanner
+RES-Scanner is a software package for genome-wide identification and annotation of RNA-editing sites for any species with matched RNA-Seq and DNA-Seq data.

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@ZhangLabSZ
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ZhangLabSZ commented on 3c3bfed Jul 25, 2015

RES-Scanner is a software package written in the Perl programming language, for genome-wide identification and annotation of RNA-editing sites for any species with matched RNA-Seq and DNA-Seq data. RES-Scanner integrates read mapping, homozygous genotype calling, de novo RNA-editing site identification and annotation in one package. It combines the advantage of BWA and BLAT to map sequencing reads, and implements statistical models and sophisticated filters to remove potential false positives resulted from genome-encoded single-nucleotide polymorphisms (SNPs), sequencing and read-mapping errors. It is capable of handling samples from an individual or a pool of multiple individuals. Furthermore, RES-Scanner can improve the completeness and accuracy of editing site identification when the data of multiple samples are available.
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