diff --git a/README.md b/README.md
index ad968c8..ed9a3e6 100644
--- a/README.md
+++ b/README.md
@@ -54,6 +54,17 @@ const options = {
 
   //Character encoding for reading/writing files (defaults to utf-8)
   encoding: 'utf8',
+
+  //Single file or glob to ignore
+  ignore: 'path/to/ignored/file',
+
+  //Multiple files or globs to ignore
+  ignore: [
+    'path/to/ignored/file',
+    'path/to/other/ignored_file',
+    'path/to/ignored_files/*.html',
+    'another/**/*.ignore',
+  ]
 };
 ```
 
@@ -122,7 +133,7 @@ const changedFiles = replace.sync({
 ### CLI usage
 
 ```sh
-replace-in-file from to some/file.js,some/**/glob.js [--isRegex]
+replace-in-file from to some/file.js,some/**/glob.js --ignore=ignore/files.js,ignore/**/glob.js [--isRegex]
 ```
 
 The flags `allowEmptyPaths` and `encoding` are supported in the CLI.
diff --git a/bin/cli.js b/bin/cli.js
index e7320cf..46bef0e 100755
--- a/bin/cli.js
+++ b/bin/cli.js
@@ -16,7 +16,7 @@ if (argv._.length < 3 && !argv.config) {
 }
 
 //Prepare vars
-let from, to, files;
+let from, to, files, ignore;
 
 //If config is set, load config file
 if (argv.config) {
@@ -41,6 +41,12 @@ if (argv.config) {
     config.files = [config.files];
   }
   files = config.files;
+
+  //Set ignore param
+  if (typeof config.ignore === 'string') {
+    config.ignore = [config.ignore];
+  }
+  ignore = config.ignore;
 }
 
 //Get from/to parameters from CLI args if not defined in config file
@@ -85,11 +91,16 @@ if (argv.isRegex) {
   }
 }
 
+//Get ignored files from ignore flag
+if (!ignore && typeof argv.ignore !== 'undefined') {
+  ignore = argv.ignore;
+}
+
 //Log
 console.log(`Replacing '${from}' with '${to}'`);
 
 //Create options
-const options = {files, from, to};
+const options = {files, from, to, ignore};
 if (typeof argv.encoding !== 'undefined') {
   options.encoding = argv.encoding;
 }
diff --git a/lib/replace-in-file.js b/lib/replace-in-file.js
index f2e7efc..2e88af1 100644
--- a/lib/replace-in-file.js
+++ b/lib/replace-in-file.js
@@ -13,6 +13,7 @@ const chalk = require('chalk');
 const defaults = {
   allowEmptyPaths: false,
   encoding: 'utf-8',
+  ignore: []
 };
 
 /**
@@ -155,9 +156,9 @@ function replaceAsync(file, from, to, enc) {
 /**
  * Promise wrapper for glob
  */
-function globPromise(pattern, allowEmptyPaths) {
+function globPromise(pattern, ignore, allowEmptyPaths) {
   return new Promise((resolve, reject) => {
-    glob(pattern, {nodir: true}, (error, files) => {
+    glob(pattern, {ignore: ignore, nodir: true}, (error, files) => {
 
       //istanbul ignore if: hard to make glob error
       if (error) {
@@ -192,17 +193,19 @@ function replaceInFile(config, cb) {
   }
 
   //Get config and globs
-  // const {files, from, to, allowEmptyPaths, encoding} = config;
+  // const {files, from, to, allowEmptyPaths, encoding, ignore} = config;
   const files = config.files;
   const from = config.from;
   const to = config.to;
   const encoding = config.encoding;
   const allowEmptyPaths = config.allowEmptyPaths;
+  const ignore = config.ignore;
   const globs = Array.isArray(files) ? files : [files];
+  const ignoreGlobs = Array.isArray(ignore) ? ignore : [ignore];
 
   //Find files
   return Promise
-    .all(globs.map(pattern => globPromise(pattern, allowEmptyPaths)))
+    .all(globs.map(pattern => globPromise(pattern, ignoreGlobs, allowEmptyPaths)))
 
     //Flatten array
     .then(files => [].concat.apply([], files))
@@ -247,18 +250,20 @@ replaceInFile.sync = function(config) {
   config = parseConfig(config);
 
   //Get config and globs
-  // const {files, from, to, encoding} = config;
+  // const {files, from, to, encoding, ignore} = config;
   const files = config.files;
   const from = config.from;
   const to = config.to;
   const encoding = config.encoding;
+  const ignore = config.ignore;
   const globs = Array.isArray(files) ? files : [files];
+  const ignoreGlobs = Array.isArray(ignore) ? ignore : [ignore];
   const changedFiles = [];
 
   //Process synchronously
   globs.forEach(pattern => {
     glob
-      .sync(pattern, {nodir: true})
+      .sync(pattern, {ignore: ignoreGlobs, nodir: true})
       .forEach(file => {
         if (replaceSync(file, from, to, encoding)) {
           changedFiles.push(file);
diff --git a/lib/replace-in-file.spec.js b/lib/replace-in-file.spec.js
index 35f16c2..19ac518 100644
--- a/lib/replace-in-file.spec.js
+++ b/lib/replace-in-file.spec.js
@@ -122,6 +122,21 @@ describe('Replace in file', () => {
       });
     });
 
+    it('should expand globs while excluding ignored files', done => {
+      replace({
+        files: 'test*',
+        ignore: 'test1',
+        from: /re\splace/g,
+        to: 'b',
+      }).then(() => {
+        const test1 = fs.readFileSync('test1', 'utf8');
+        const test2 = fs.readFileSync('test2', 'utf8');
+        expect(test1).to.equal('a re place c');
+        expect(test2).to.equal('a b c');
+        done();
+      });
+    });
+
     it('should replace substrings', done => {
       replace({
         files: 'test1',
@@ -352,6 +367,21 @@ describe('Replace in file', () => {
       });
     });
 
+    it('should expand globs while excluding ignored files', done => {
+      replace({
+        files: 'test*',
+        ignore: 'test1',
+        from: /re\splace/g,
+        to: 'b',
+      }, () => {
+        const test1 = fs.readFileSync('test1', 'utf8');
+        const test2 = fs.readFileSync('test2', 'utf8');
+        expect(test1).to.equal('a re place c');
+        expect(test2).to.equal('a b c');
+        done();
+      });
+    });
+
     it('should not return an error on success', done => {
       replace({
         files: 'test1',