diff --git a/.changeset/eight-spiders-help.md b/.changeset/eight-spiders-help.md
new file mode 100644
index 0000000000..c916b2e375
--- /dev/null
+++ b/.changeset/eight-spiders-help.md
@@ -0,0 +1,11 @@
+---
+"@spectrum-css/calendar": patch
+"@spectrum-css/combobox": patch
+"@spectrum-css/datepicker": patch
+"@spectrum-css/menu": patch
+"@spectrum-css/picker": patch
+"@spectrum-css/slider": patch
+"@spectrum-css/stepper": patch
+---
+
+Build change to remove the `postcss-preset-env` polyfill for the dist output of `:not` selectors containing multiple selectors, to avoid an unintended increase in specificity, which caused some visual regressions.
diff --git a/postcss.config.js b/postcss.config.js
index df94f0a64b..46d441e08f 100644
--- a/postcss.config.js
+++ b/postcss.config.js
@@ -118,7 +118,6 @@ module.exports = ({
 					// https://github.com/jsxtools/focus-within
 					"focus-within-pseudo-class": true,
 					"font-format-keywords": true,
-					"not-pseudo-class": true,
 					"opacity-percentage": true,
 					// https://github.com/csstools/postcss-plugins/tree/main/plugins/css-prefers-color-scheme
 					"prefers-color-scheme-query": true,