@alekseyzimin alekseyzimin released this Aug 29, 2018 · 5 commits to master since this release

Assets 3

This release has major assembly quality improvements and some cosmetic changes.

-- reworked the joining algorithm for incorporating long high error read sequence into the corrected reads where the sequence could not be corrected by Illumina data
-- cleaned up the code and the output/error messages
-- added final gapclosing step for scaffold gaps spanned by long high error reads
-- bugfixes, such as error in executing do_consensus.sh on some systems
-- re-enabled overlap based trimming in CABOG assembler and reduced the default coverage input for correction to 25x; if you have more than 25x coverage, the assembler will use 25x coverage in the longest reads

The changes made significant impact on contiguity and correctness of large mammalian and plant genome assemblies, for some of my test assemblies now N50 contig increased from ~300Kbp to ~950Kbp on 20x Pacbio + 100x Illumina data set. The run time has increased about 10% over 3.2.7 release but still faster than 3.2.6 release.