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cff-version: 1.3.0
message: >-
If you use this software, please cite both the software itself, as well as the
article Lancaster AK et al. (2024) <a
href="https://doi.org/10.3389/fimmu.2024.1378512">PyPop: A mature open-source
software pipeline for population genomics</a>. <i>Front. Immunol.</i>
<b>15</b>:1378512. doi: 10.3389/fimmu.2024.1378512
abstract: >-
<p>PyPop for Population Genomics (<a href="http://pypop.org/">PyPop</a>) is a
Python program for processing genotype and allele data and running population
genetic analyses, including conformity to Hardy-Weinberg expectations; tests
for balancing or directional selection; estimates of haplotype frequencies and
measures and tests of significance for linkage disequilibrium
(LD). Output of analyses are stored in XML format for maximum downstream
flexibility. PyPop also has an internal facility for additionally aggregating
the output XML and generating output tab-separated values (TSV) files, as well
as default plain text files for each population. Although it can be run on any
kind of genotype data, it has additional support for analyzing population
genotype with allelic nomenclature from the human leukocyte antigen (HLA)
region.</p>
authors:
- family-names: Lancaster
given-names: Alexander K.
orcid: https://orcid.org/0000-0002-0002-9263
affiliation:
- Amber Biology LLC
- name: RIIS 2.0
ror: https://ror.org/000xkb537
- name: Institute for Globally Distributed Open Research and Education
ror: https://ror.org/01643wd06
- family-names: Nelson
given-names: Mark P.
affiliation:
- name: University of California, Berkeley
ror: https://ror.org/01an7q238
- family-names: Single
given-names: Richard
orcid: https://orcid.org/0000-0001-6054-6505
affiliation:
- name: University of Vermont
ror: https://ror.org/0155zta11
- family-names: Solberg
given-names: Owen
orcid: https://orcid.org/0000-0003-3060-9709
- family-names: Tsai
given-names: Yingsu
affiliation:
- name: University of California, Berkeley
ror: https://ror.org/01an7q238
orcid: https://orcid.org/0009-0006-0162-6066
- family-names: Meyer
given-names: Diogo
orcid: https://orcid.org/0000-0002-7155-5674
affiliation:
- name: University of São Paulo
ror: https://ror.org/036rp1748
- family-names: Webster
given-names: Gordon
affiliation:
- name: Amber Biology LLC
orcid: https://orcid.org/0009-0009-2862-0467
- family-names: Mariani
given-names: Michael P.
orcid: https://orcid.org/0000-0001-5852-0517
affiliation:
- name: Mariani Systems LLC
- name: University of Vermont
ror: https://ror.org/0155zta11
- family-names: Sochat
given-names: Vanessa
orcid: https://orcid.org/0000-0002-4387-3819
affiliation:
- name: Lawrence Livermore National Laboratory
ror: https://ror.org/041nk4h53
- family-names: Kornel
given-names: Karl
orcid: https://orcid.org/0000-0001-5847-5330
affiliation: Stanford Research Computing Center
- family-names: Spaaks
given-names: Jurriaan H.
orcid: https://orcid.org/0000-0002-7064-4069
affiliation:
- name: Netherlands eScience Center
ror: https://ror.org/00rbjv475
- family-names: Mack
given-names: Steven J.
orcid: https://orcid.org/0000-0001-9820-9547
affiliation:
- name: University of California, San Francisco
ror: https://ror.org/043mz5j54
- family-names: Thomson
given-names: Glenys
orcid: https://orcid.org/0000-0001-5235-4159
affiliation:
- name: University of California, Berkeley
ror: https://ror.org/01an7q238
title: 'PyPop: Python for Population Genomics'
repository-artifact: https://pypi.org/project/pypop-genomics/
repository-code: https://github.com/alexlancaster/pypop/
license: GPL-2.0-or-later
version: v1.4.2
type: software
url: http://pypop.org/
identifiers:
- description: PyPop homepage
type: url
value: http://pypop.org/
relation: IsSupplementedBy
- description: PyPop documentation
type: url
value: http://pypop.org/docs
relation: IsDocumentedBy
- description: Previous Tissue Antigens (2007) publication
type: doi
value: 10.1111/j.1399-0039.2006.00769.x
relation: Continues
- description: Preprint version of TA (2007) publication
type: url
value: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369784
relation: Continues
- description: GitHub tag for repository
type: url
value: https://github.com/alexlancaster/pypop/tree/v1.4.2
relation: IsSupplementTo
- description: PyPI package
type: url
value: https://pypi.org/project/pypop-genomics/1.4.2
relation: IsSourceOf
- description: DOI concept identifier for all versions of PyPop
type: doi
value: 10.5281/zenodo.10080667
relation: IsVersionOf
keywords:
- population genetics
- population genomics
- bioinformatics
- computational biology
- evolutionary biology
- Human leukocyte antigen
- Major histocompatibility complex
- HLA
- MHC
doi: 10.5281/zenodo.22033413