Estimation of Interpretable eQTL Effect Sizes Using a Log of Linear Model
R C
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DESCRIPTION
NAMESPACE
README.md

README.md

ACMEeqtl: Estimation of Interpretable eQTL Effect Sizes Using a Log of Linear Model

We use a non-linear model, termed ACME, that reflects a parsimonious biological model for allelic contributions of cis-acting eQTLs. With non-linear least-squares algorithm we estimate maximum likelihood parameters. The ACME model provides interpretable effect size estimates and p-values with well controlled Type-I error. Includes both R and (much faster) C implementations. For more details see Palowitch et al. (2017) .

Installation

Install CRAN Version

To install the CRAN version of ACMEeqtl, run

install.packages("ACMEeqtl")

Install GitHub Version

To install ACMEeqtl directly from GitHub, run

devtools::install_github("andreyshabalin/ACMEeqtl")

If devtools package is missing, it can be installed with

install.packages("devtools")