diff --git a/doc/source/conf.py b/doc/source/conf.py
index ffe438126..ef633da33 100644
--- a/doc/source/conf.py
+++ b/doc/source/conf.py
@@ -60,6 +60,7 @@
         "StaticMixer_001.cfx",
         "StaticMixer_001.def",
     ],
+    "python_uv": ["project_setup.py", "exec_script.py", "eval.py"],
 }
 
 sys.path.append(os.path.abspath(os.path.dirname(__file__)))
diff --git a/doc/source/examples/ex_python_uv.rst b/doc/source/examples/ex_python_uv.rst
new file mode 100644
index 000000000..2f142674c
--- /dev/null
+++ b/doc/source/examples/ex_python_uv.rst
@@ -0,0 +1,171 @@
+.. _example_python_uv:
+
+.. note::
+
+    Go to the `bottom of this page`_ to download the ZIP file for the uv example.
+
+Run arbitrary Python scripts on HPS
+===================================
+
+This example shows how to run arbitrary Python scripts. It uses
+the `uv <https://docs.astral.sh/uv/>`__ package to generate the required
+environments on the fly.
+
+The example sets up a project that plots ``sin(x)`` using NumPy and
+Matplotlib and then saves the figure to a file.
+
+The metadata header present in the ``eval.py`` script, which defines the
+dependencies, enables uv to take care of the environment setup:
+
+.. code:: python
+
+   # /// script
+   # requires-python = "==3.12"
+   # dependencies = [
+   #     "numpy",
+   #     "matplotlib"
+   # ]
+   # ///
+
+For more information, see `Inline script metadata
+<https://packaging.python.org/en/latest/specifications/inline-script-metadata/#inline-script-metadata>`__
+in the *Python Packaging User Guide* and `Running a script with dependencies <https://docs.astral.sh/uv/guides/scripts/#running-a-script-with-dependencies>`__
+in the uv documentation.
+
+Prerequisites
+=============
+
+For the example to run, uv must be installed and registered
+on the scaler/evaluator. For installation instructions, see
+`Installing uv <https://docs.astral.sh/uv/getting-started/installation/>`__
+in the uv documentation.
+
+Once uv is installed, the package must be registered in the
+scaler/evaluator with the following properties:
+
+.. list-table::
+   :header-rows: 1
+
+   * - Property
+     - Value
+   * - Name
+     - uv
+   * - Version
+     - 0.7.19
+   * - Installation Path
+     - /path/to/uv
+   * - Executable
+     - /path/to/uv/bin/uv
+
+Be sure to adjust the version to the one you have installed.
+
+Define a custom cache directory
+-------------------------------
+
+The preceding steps set up uv with the cache located in its default location
+in the user home directory (~/.cache/uv). Depending on your
+situation, you might prefer a different cache location, such as a shared
+directory accessible to all evaluators. To define a custom uv
+cache directory, add the following environment variable to the
+uv package registration in the scaler/evaluator:
+
+.. list-table::
+   :header-rows: 1
+
+   * - Environment Variable
+     - Value
+   * - UV_CACHE_DIR
+     - /path/to/custom/uv/cache/dir
+
+Create offline air-gapped setups
+--------------------------------
+
+If internet is not available, you can create offline air-gapped setups for uv
+using one of these options:
+
+* Pre-populate the uv cache with all desired dependencies.
+* Provide a local Python package index and set uv to use it. For
+  more information, see
+  `Package indexes <https://docs.astral.sh/uv/configuration/indexes/>`__
+  in the uv documentation. This index can then sit in a shared location,
+  with node-local caching applied.
+* Use pre-generated virtual environments. For more information, see
+  `uv venv <https://docs.astral.sh/uv/reference/cli/#uv-venv>`__ in the
+  uv documentation.
+
+To turn off network access, you can either set the
+``UV_OFFLINE`` environment variable or use the ``--offline`` flag with
+many uv commands.
+
+Run the example
+===============
+
+To run the example, execute the ``project_setup.py`` script::
+
+  uv run project_setup.py
+
+This command sets up a project with a number
+of jobs. Each job generates a ``plot.png`` file.
+
+Options
+-------
+
+The example supports the following command line arguments:
+
+.. list-table::
+   :header-rows: 1
+
+   * - Flag
+     - Example
+     - Description
+   * - ``-U``, ``--url``
+     - ``--url=https://localhost:8443/hps``
+     - URL of the target HPS instance
+   * - ``-u``, ``--username``
+     - ``--username=repuser``
+     - Username to log into HPS
+   * - ``-p``, ``--password``
+     - ``--password=topSecret``
+     - Password to log into HPS
+   * - ``-j``, ``--num-jobs``
+     - ``--num-jobs=10``
+     - Number of jobs to generate
+
+Files
+-----
+
+Descriptions follow of the relevant example files.
+
+The project creation script, ``project_setup.py``, handles all communication with the
+HPS instance, defines the project, and generates the jobs.
+
+.. literalinclude:: ../../../examples/python_uv/project_setup.py
+    :language: python
+    :lines: 23-
+    :caption: project_setup.py
+
+The script ``eval.py``, which is evaluated on HPS, contains the code to plot a sine and then save 
+the figure.
+
+.. literalinclude:: ../../../examples/python_uv/eval.py
+    :language: python
+    :lines: 23-
+    :caption: eval.py
+
+The execution script, ``exec_script.py``, uses uv to run the evaluation script.
+
+.. literalinclude:: ../../../examples/python_uv/exec_script.py
+    :language: python
+    :lines: 23-
+    :caption: exec_script.py
+
+Download the ZIP file for the uv example and use
+a tool such as 7-Zip to extract the files.
+
+.. _bottom of this page:
+
+.. button-link:: ../_downloads/python_uv.zip
+    :color: black
+    :expand:
+
+    Download ZIP file
\ No newline at end of file
diff --git a/doc/source/examples/index.rst b/doc/source/examples/index.rst
index 3e6f5f54f..99d41f08f 100644
--- a/doc/source/examples/index.rst
+++ b/doc/source/examples/index.rst
@@ -35,6 +35,7 @@ one :download:`ZIP file <../../../build/pyhps_examples.zip>`.
   ex_fluent_nozzle
   ex_cfx_static_mixer
   ex_python_two_bar
+  ex_python_uv
 
 .. list-table::
    :header-rows: 1
@@ -59,9 +60,11 @@ one :download:`ZIP file <../../../build/pyhps_examples.zip>`.
      - Submit a CFX solve job to the HPS server using an execution script.
    * - :ref:`example_python_two_bar`
      - Create an HPS project that solves a two-bar truss problem with Python.
+   * - :ref:`example_python_uv`
+     - Run arbitrary Python scripts on HPS using uv.
 
 A link to download the required resources is available on each example page. If desired, 
-you can download the required resources for all examples through the link below.
+you can download the required resources for all examples using the following link.
 
 .. _bottom of this page:
 
diff --git a/doc/styles/config/vocabularies/ANSYS/accept.txt b/doc/styles/config/vocabularies/ANSYS/accept.txt
index 9f40ae5f3..5a3f700d4 100644
--- a/doc/styles/config/vocabularies/ANSYS/accept.txt
+++ b/doc/styles/config/vocabularies/ANSYS/accept.txt
@@ -9,10 +9,14 @@ isort
 [Kk]eycloak
 Koenig
 marshmallow_oneofschema
+Matplotlib
+NumPy
 Mises
 postprocess
 [Pp]ydantic
 pytest
 subpackage
+uv
+venv
 von
 Wintermantel
\ No newline at end of file
diff --git a/examples/python_uv/eval.py b/examples/python_uv/eval.py
new file mode 100644
index 000000000..abaae2b80
--- /dev/null
+++ b/examples/python_uv/eval.py
@@ -0,0 +1,50 @@
+# Copyright (C) 2022 - 2025 ANSYS, Inc. and/or its affiliates.
+# SPDX-License-Identifier: MIT
+#
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in all
+# copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+# SOFTWARE.
+
+# /// script
+# requires-python = "==3.12"
+# dependencies = [
+#     "numpy",
+#     "matplotlib"
+# ]
+# ///
+
+
+import matplotlib.pyplot as plt
+import numpy as np
+
+if __name__ == "__main__":
+    # Generate plot
+    ts = np.linspace(0.0, 10.0, 100)
+    ys = np.sin(ts)
+
+    fig, ax = plt.subplots()
+    ax.plot(ts, ys)
+    ax.set_xlabel("Time [s]")
+    ax.set_ylabel("Displacement [cm]")
+    plt.savefig("plot.png", dpi=200)
+
+    # Uncomment to enable venv cleanup in exec script, see execution script for details
+    # import json
+    # import sys
+    # with open("output_parameters.json", "w") as out_file:
+    #    json.dump({"exe": sys.executable}, out_file, indent=4)
diff --git a/examples/python_uv/exec_script.py b/examples/python_uv/exec_script.py
new file mode 100644
index 000000000..bccecdfb1
--- /dev/null
+++ b/examples/python_uv/exec_script.py
@@ -0,0 +1,88 @@
+# Copyright (C) 2022 - 2025 ANSYS, Inc. and/or its affiliates.
+# SPDX-License-Identifier: MIT
+#
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in all
+# copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+# SOFTWARE.
+
+"""Simple execution script for Python with uv.
+
+Command formed: uv run <script_file>
+"""
+
+import json
+import os
+import shutil
+
+from ansys.rep.common.logging import log
+from ansys.rep.evaluator.task_manager import ApplicationExecution
+
+
+class PythonExecution(ApplicationExecution):
+    def execute(self):
+        log.info("Start uv execution script")
+
+        # Identify files
+        script_file = next((f for f in self.context.input_files if f["name"] == "eval"), None)
+        assert script_file, "Python script file missing"
+        output_filename = "output_parameters.json"
+
+        # Identify applications
+        app_uv = next((a for a in self.context.software if a["name"] == "uv"), None)
+        assert app_uv, "Cannot find app uv"
+
+        # Add " around exe if needed for Windows
+        exes = {"uv": app_uv["executable"]}
+        for k, v in exes.items():
+            if " " in v and not v.startswith('"'):
+                exes[k] = f'"{v}"'  # noqa
+
+        # Pass env vars correctly
+        env = dict(os.environ)
+        env.update(self.context.environment)
+
+        ## Run evaluation script
+        cmd = f"{exes['uv']} run {script_file['path']}"
+        self.run_and_capture_output(cmd, shell=True, env=env)
+
+        # Read eval.py output parameters
+        output_parameters = {}
+        try:
+            log.debug(f"Loading output parameters from {output_filename}")
+            with open(output_filename) as out_file:
+                output_parameters = json.load(out_file)
+            self.context.parameter_values.update(output_parameters)
+            log.debug(f"Loaded output parameters: {output_parameters}")
+        except Exception as ex:
+            log.info("No output parameters found.")
+            log.debug(f"Failed to read output_parameters from file: {ex}")
+
+        # If exe path is in out params, delete the venv folder to avoid runaway uv venv cache
+        # See https://github.com/astral-sh/uv/issues/13431
+        if "exe" in output_parameters.keys():
+            try:
+                venv_cache = os.path.abspath(os.path.join(output_parameters["exe"], "..", ".."))
+                if os.path.exists(venv_cache):
+                    log.debug(f"Cleaning venv cache at {venv_cache}...")
+                    shutil.rmtree(venv_cache)
+                else:
+                    log.debug(f"Venv cache path {venv_cache} does not exist.")
+            except Exception as ex:
+                log.debug(f"Couldn't clean venv cache at {venv_cache}: {ex}")
+
+        log.info("End Python execution script")
diff --git a/examples/python_uv/project_setup.py b/examples/python_uv/project_setup.py
new file mode 100644
index 000000000..46afac654
--- /dev/null
+++ b/examples/python_uv/project_setup.py
@@ -0,0 +1,151 @@
+# Copyright (C) 2022 - 2025 ANSYS, Inc. and/or its affiliates.
+# SPDX-License-Identifier: MIT
+#
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in all
+# copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+# SOFTWARE.
+
+# /// script
+# requires-python = "==3.10"
+# dependencies = [
+#     "ansys-hps-client",
+#     "packaging"
+# ]
+# ///
+
+"""Python with uv example."""
+
+import argparse
+import logging
+import os
+
+from ansys.hps.client import Client, HPSError
+from ansys.hps.client.jms import (
+    File,
+    JmsApi,
+    Job,
+    JobDefinition,
+    Project,
+    ProjectApi,
+    ResourceRequirements,
+    Software,
+    SuccessCriteria,
+    TaskDefinition,
+)
+
+log = logging.getLogger(__name__)
+
+
+def create_project(client, num_jobs):
+    log.debug("=== Create Project")
+    jms_api = JmsApi(client)
+    proj = jms_api.create_project(
+        Project(
+            name=f"Python UV example - {num_jobs} jobs",
+            priority=1,
+            active=True,
+        ),
+        replace=True,
+    )
+    project_api = ProjectApi(client, proj.id)
+
+    log.debug("=== Define Files")
+    cwd = os.path.dirname(__file__)
+    # Input Files
+    files = [
+        File(
+            name="eval",
+            evaluation_path="eval.py",
+            type="text/plain",
+            src=os.path.join(cwd, "eval.py"),
+        ),
+        File(
+            name="exec_script",
+            evaluation_path="exec_script.py",
+            type="text/plain",
+            src=os.path.join(cwd, "exec_script.py"),
+        ),
+        File(
+            name="plot",
+            evaluation_path="plot.png",
+            type="image/png",
+            collect=True,
+        ),
+    ]
+    files = project_api.create_files(files)
+    file_ids = {f.name: f.id for f in files}
+
+    log.debug("=== Define Task")
+    task_def = TaskDefinition(
+        name="plotting",
+        software_requirements=[Software(name="uv")],
+        resource_requirements=ResourceRequirements(
+            num_cores=0.5,
+            memory=100 * 1024 * 1024,  # 100 MB
+            disk_space=10 * 1024 * 1024,  # 10 MB
+        ),
+        execution_level=0,
+        max_execution_time=500.0,
+        use_execution_script=True,
+        execution_script_id=file_ids["exec_script"],
+        execution_command="%executable% run %file:eval%",
+        input_file_ids=[file_ids["eval"]],
+        output_file_ids=[file_ids["plot"]],
+        success_criteria=SuccessCriteria(
+            return_code=0,
+            require_all_output_files=True,
+        ),
+    )
+    task_defs = project_api.create_task_definitions([task_def])
+
+    print("== Define Job")
+    job_def = JobDefinition(
+        name="JobDefinition.1", active=True, task_definition_ids=[task_defs[0].id]
+    )
+    job_def = project_api.create_job_definitions([job_def])[0]
+    log.debug(f"== Create {num_jobs} Jobs")
+    jobs = []
+    for i in range(num_jobs):
+        jobs.append(Job(name=f"Job.{i}", eval_status="pending", job_definition_id=job_def.id))
+    project_api.create_jobs(jobs)
+    log.info(f"Created project '{proj.name}', ID='{proj.id}'")
+    return proj
+
+
+if __name__ == "__main__":
+    parser = argparse.ArgumentParser()
+    parser.add_argument("-j", "--num-jobs", type=int, default=10)
+    parser.add_argument("-U", "--url", default="https://localhost:8443/hps")
+    parser.add_argument("-u", "--username", default="repuser")
+    parser.add_argument("-p", "--password", default="repuser")
+    args = parser.parse_args()
+
+    logger = logging.getLogger()
+    logging.basicConfig(format="%(message)s", level=logging.DEBUG)
+
+    try:
+        log.info("Connect to HPC Platform Services")
+        client = Client(url=args.url, username=args.username, password=args.password)
+        log.info(f"HPS URL: {client.url}")
+        proj = create_project(
+            client=client,
+            num_jobs=args.num_jobs,
+        )
+
+    except HPSError as e:
+        log.error(str(e))