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| <title>The Only Remedy Is a Cure Campaign. The Juvenile Diabetes Foundation. July 31, | |
| 1998.</title> | |
| <meta name="description" content="The Only Remedy Is a Cure Campaign, JDF's international major gifts initiative, | |
| provides financial stability to researchers."> | |
| <meta name="keywords" content="diabetes, type 1, type I, juvenile diabetes, IDDM, The Only Remedy Is a Cure Campaign"> | |
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| <p><a name="top"></a></p> | |
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| <td rowspan="2" width="15" align="center"><img src="pubinfo/images/junepicts/stele.gif" hspace="0" vspace="0" border="0" alt WIDTH="15" HEIGHT="1"></td> | |
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| <td><br> | |
| <p align="center"><font size="+2" face="Helvetica, Arial,sans-serif">The Only Remedy Is a | |
| Cure Campaign</font></p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Campaign Overview</font> | |
| <br> | |
| JDF has a focused mission: <b>to find a cure for diabetes and its complications through | |
| the support of research.</b> Twenty-eight years ago, when JDF began its search for the | |
| cure, little was known about diabetes: what caused it; who would get it; why it caused | |
| health complications; or how to treat those complications. Research funded and stimulated | |
| by JDF has changed that. Our knowledge of the disease has grown enormously: <ul> | |
| <li>We know that Type I diabetes is an autoimmune disease, in which the body attacks itself, | |
| destroying the insulin-producing beta cells in the pancreas. </li> | |
| <li>We know there is not one gene, but a combination of genetic traits and environmental | |
| triggers which cause the disease. </li> | |
| <li>We can predict who is at risk for diabetes and detect its earliest signs. </li> | |
| <li>We have scientific proof that tight control of blood sugar reduces complications. </li> | |
| <li>We can treat diabetic retinopathy and periodontal disease, reduce the necessity of lower | |
| limb amputations, and control high blood pressure to lessen kidney and cardiovascular | |
| complications. </li> | |
| <li>We can greatly enhance fetal health and birth outcome in women with diabetes.</li> | |
| </ul> | |
| <p>To achieve our mission, all relevant and promising research and clinical applications | |
| must be considered for funding. JDF’s Board believes that to hasten our progress to a | |
| cure we must fund a diversified “portfolio” of research focused on: <ul> | |
| <li>prevention of diabetes in those who are at risk, and of reoccurrence in those who have | |
| been cured by transplantation; </li> | |
| <li>attainment of normal blood glucose levels through biological and | |
| bioelectrical-mechanical means, and </li> | |
| <li>the prevention and mitigation of the consequences of diabetes. </li> | |
| </ul> | |
| <p>During our twenty-eight years JDF has made grants of more than $290 million for | |
| diabetes research, and plans to elevate the pace of research further this year with grants | |
| totaling over $40 million.</p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Grant Review Process</font> | |
| <br> | |
| JDF’s sponsorship of significant and productive research is not coincidental. JDF has | |
| built a system of senior scientist directed research review based upon the careful | |
| deliberation of two JDF committees: a Medical Science Review Committee (MSRC) to judge | |
| each application on scientific merit; followed by a Lay Review Committee which selects | |
| from the MSRC recommendations those projects which seem most likely to help JDF achieve a | |
| cure for diabetes and an end to its complications.</p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Contributors</font> <br> | |
| This rigorous review process has earned the respect and leadership support from several | |
| significant corporations including: Becton Dickinson Company, Novo Nordisk, The Coca-Cola | |
| Company, Compaq Computer Corp., FIFTY 50 Foods, and Mistic Brands. A number of prominent | |
| foundations, as well, rely on JDF to select promising research grants for their ongoing | |
| contributions. This enables them to avoid creating a costly internal process to solicit, | |
| review, and fund individual research proposals.</p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Leadership</font> <br> | |
| JDF provides more money for diabetes research than any other non-profit, non-governmental | |
| organization in the world. In terms of total dollars awarded to research, JDF now ranks | |
| third among <i>all</i> non-profit, non-governmental health organizations in the world. | |
| Moreover, JDF ranks <i>first </i>of all major health agencies<i> </i>in the percentage of | |
| funds raised that is allocated directly to research. Furthermore, of the private health | |
| organizations funding research, the percentage of its revenue JDF spends on fund raising | |
| is among the lowest. This unparalleled efficiency reflects the relentless commitment to | |
| finding a cure by JDF’s volunteers and supporters. The December, 1997 issue of <a href="Smart Money.htm">Smart Money</a> magazine named JDF as one of the 10 most | |
| efficient and trustworthy charities in the United States—and only one of two in the | |
| field of health and medicine. </p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Efficiency</font> <br> | |
| During the fiscal year ending June 30, 1997, JDF’s total support and revenue was | |
| $75,083,582. JDF committed $31,491,974 (59%) to its research program of over 350 grants to | |
| scientists in 15 countries on four continents, including 29 states in the U.S. and four | |
| provinces in Canada; $11,504,082 (21%) for public diabetes education; $2,488,582 (5%) for | |
| management and general purposes, and $8,280,119 (15%) for fund raising. </p> | |
| <p><b><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+2">The Only Remedy | |
| Is a Cure Campaign</font></b> <br> | |
| JDF’s success is largely due to <b>The Only Remedy Is a Cure Campaign</b>, an | |
| international major gifts initiative begun in 1990. Pioneering the public/private | |
| partnership concept in biomedical research, the Campaign has now secured <u>new research | |
| dollars</u> from government sources, matching the efforts of individuals, foundations, and | |
| corporations. As of August, 1998 more than $181.5 million has been raised toward a $200 | |
| million goal. </p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Partnerships</font> <br> | |
| In 1992, in the single most ambitious enterprise in the history of diabetes research, JDF | |
| and its first public partner, the National Institute of Diabetes and Digestive and Kidney | |
| Diseases (NIDDK), launched six Diabetes Interdisciplinary Research Programs the first such | |
| programs in the world. These research programs team world-class diabetes researchers with | |
| scientists specializing in molecular biology, biophysics, genetics, immunology, and other | |
| cutting-edge areas of biomedical investigation. </p> | |
| <p>The effectiveness of this partnership (which led to a second JDF/NIDDK partnership in | |
| 1994 and a third JDF/NIDDK partnership in 1997), along with JDF’s successful | |
| fund-raising efforts, convinced other government entities to join with JDF. To date, JDF | |
| has entered into agreements with four of the U.S. National Institutes of Health, the | |
| Department of Veterans Affairs, the Medical Research Council of Canada, National Health | |
| and Medical Research Council of Australia, and the Wallenberg Foundation/Swedish Medical | |
| Research Council to develop additional five-year, multi-million dollar interdisciplinary | |
| programs that now number 42 worldwide.</p> | |
| <p><b>The Only Remedy Is a Cure Campaign</b> provides financial stability to researchers | |
| which allows for both long term research commitments and rapid exploration of promising | |
| new research ideas and strategies. In the near future, JDF-funded research holds the | |
| promise for: <ul> | |
| <li>successful islet transplantation without dangerous systemic immunosuppression; </li> | |
| <li>prevention of diabetes in those who are at risk, and of reoccurrence in those who have | |
| been cured by transplantation; </li> | |
| <li>creation of an early detection system for kidney disease, preventing the need for | |
| dialysis and transplantation; </li> | |
| <li>“immunization” against diabetes, and </li> | |
| <li>clinical application of basic research developments.</li> | |
| </ul> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">Role of Philanthropy</font> | |
| <br> | |
| A cure for diabetes will likely be achieved in several stages, and from a combination of | |
| sources. It is imperative, therefore, that JDF continue to fund many different areas of | |
| basic and clinical research, continue to promote the interdisciplinary approach, and | |
| increase the number of senior scientists involved in the task. This is all done through | |
| the generous contributions of the JDF Board of Trustees and thousands of volunteers and | |
| supporters.</p> | |
| <p><font color="#aa2b4a" face="Helvetica, Arial,sans-serif" size="+1">For More Information</font> | |
| <br> | |
| For more information on JDF’s The Only Remedy is a Cure Campaign and how you might | |
| join in our efforts to fund research for the cure, please contact Mark Monty at | |
| 1-800-JDF-CURE or via e-mail at <a href="mailto:mmonty@jdfcure.org">mmonty@jdfcure.org</a>.</p> | |
| <p><br> | |
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