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| <title>Juvenile Diabetes Foundation - A Clear and Simple Vision</title> | |
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| <table border="0"> | |
| <tr> | |
| <td width="120"><a href="index.html"><img src="images/p-abt.gif" alt="JDF" border="0" width="84" height="45"></a></td> | |
| <td align="center"><font size="6"><strong>Many Voices, | |
| One Goal</strong></font></td> | |
| </tr> | |
| </table> | |
| <p> </p> | |
| <p><font size="4"><strong>Many Voices, One Goal</strong></font></p> | |
| <p>As surprising as it seems to some people, the Juvenile | |
| Diabetes Foundation International (JDFI) does not exist to fund | |
| research. It exists in the belief that its efforts will help | |
| bring about an end to the disease, to discover a cure. Toward | |
| that goal, research is a means, not the end itself. We use our | |
| funds — our donors’ funds, your funds — to support | |
| the best research because it represents the major hope for | |
| prevention and eradication of diabetes and its devastating | |
| consequences.</p> | |
| <p>We are fully aware that the most exacting bench research, the | |
| boldest clinical trial, the most promising technology mean | |
| nothing if the result is not ultimately a cure for the disease. | |
| That’s why all of us who are involved with JDFI and its work | |
| have committed — and recommitted — ourselves to the | |
| search for a cure.</p> | |
| <p>On the following pages, you will walk a pathway into the | |
| hearts of people who play special roles in this search.</p> | |
| <p>Here are the voices of some of the parents who, on hearing the | |
| disheartening diagnosis of a child’s illness, helped create | |
| JDFI and who continue to lead the organization today…</p> | |
| <p>some of the parents who, confident that their stricken | |
| children and others like them can be helped, work as volunteers | |
| to provide guidance…some of the many researchers who, | |
| certain that science will ultimately produce the sought-after | |
| cure, work tirelessly toward that end…some of the countless | |
| JDFI private and public partners whose contributions make the | |
| scientists’ research possible. Finally, here are the voices | |
| of some of our many members and friends around the world who | |
| believe in and share our goals.</p> | |
| <p>One goal, actually. To be known, together, as the people who | |
| cured diabetes.</p> | |
| <p>The leadership of parents of children with diabetes led to the | |
| founding of JDFI, and sustains the organization today…The | |
| mold for the Juvenile Diabetes Foundation International was cast | |
| by the personal, passionate commitment of our founders. That same | |
| fierce covenant motivates today’s volunteer leadership and | |
| keeps us focused on the only thing that is important: a cure.</p> | |
| <p>Take, for example, the words of Carol Lurie, a founding member | |
| of JDFI and still an active volunteer 27 years later. "I | |
| remember the day my son Steve was diagnosed the way I remember | |
| Pearl Harbor," she says, "as a day that would change | |
| everything forever. It was thirty years ago, and he was at summer | |
| camp. Looking back, I realize I had missed the now-so-obvious | |
| symptoms: the relentless thirst, the frequent urination...."</p> | |
| <p>Carol’s reaction to her son’s disease was typical of | |
| how JDFI’s parents respond — sometimes, as she says, | |
| "as a means of self-preservation" during those initial | |
| days and weeks while the significance of the diagnosis sinks in, | |
| but then, with an inflexible commitment to play their part in the | |
| search for a cure.</p> | |
| <p>"We learned about the young organization JDFI and its | |
| visionary founder Lee Ducat, and we became determined to help it | |
| grow," says Carol. "We worked and watched as government | |
| took its place as the major funder of diabetes research. And | |
| looking for additional support, we went to both individuals and | |
| major corporations. We had one aim: to try to make life better | |
| for our child and others like him."</p> | |
| <p>Thinking back on her efforts, Carol smiles. "Twenty-seven | |
| years isn’t a long time in the history of scientific | |
| research, but it can be a lifetime if your child has | |
| diabetes."</p> | |
| <p>At JDFI today, the new generation of leadership is no less | |
| passionate in its commitment. </p> | |
| <p>"I have to search deep in my memory to recall what a life | |
| without diabetes is like," says Sandy Silvestri, a member of | |
| the JDFI Board. Her awakening to the affliction came suddenly | |
| some five years ago when, on a November morning, she could not | |
| rouse her two-year-old son from a deep sleep. "We drove to | |
| the emergency room with Joey in my arms," she says. | |
| "He’d been sick for a few days, and a doctor had put | |
| him on antibiotics. Only when he slipped into a coma did we find | |
| out what was really wrong. That day changed everything in our | |
| lives, which have been ruled by diabetes ever since."</p> | |
| <p>Sandy explains that she once asked a researcher who himself | |
| had diabetes what he considered the most serious complication of | |
| the disease. "He told me it was the minute-to-minute demands | |
| on his mind, the accounting for diabetes, no matter what else he | |
| was doing."</p> | |
| <p>"For him," she comments, "as for us, diabetes | |
| always has to come first."</p> | |
| <p>The same holds true for all of us at JDFI, diabetes — and | |
| the search for a cure.</p> | |
| <p>Naturally, as parents of children with diabetes, those | |
| volunteers who ensure the research we fund meets our mission take | |
| their responsibilities personally…With an understanding that | |
| only a parent can have, these volunteers support the researchers | |
| striving to end our search for a cure. Theirs is a natural | |
| dedication. There is no greater force than the passion of the | |
| people who not only desire a cure, but who need a cure.</p> | |
| <p>Take Emily Spitzer, for example, who serves as the volunteer | |
| Chair of Research for JDFI, and whose daughter, Rebecca, has | |
| diabetes. "My daughter," says Emily, "often asks | |
| if what I’m doing for the foundation will make her life | |
| better.</p> | |
| <p>It’s a question that I ask myself constantly, and I ask | |
| it of our researchers as well. By asking, it’s easy to keep | |
| in mind that we’re not in the business of funding science | |
| for the sake of science. We want answers, for my daughter and for | |
| others’ sons and daughters. We don’t want studies | |
| — but interventions that prevent diabetes, maintain normal | |
| blood sugar, prevent complications."</p> | |
| <p>With the full realization that answers do not come without | |
| expense and effort, JDFI recently assembled a Research Task Force | |
| to evaluate all current research in diabetes, along with our | |
| research funding. A process called "mapping" will help | |
| us to determine where JDFI dollars should go, whether there are | |
| substantive areas in which we should concentrate, and the funding | |
| vehicles that we should use to achieve our mission. The results | |
| will aid us in moving to the next step, taking research from the | |
| laboratory bench to the patient’s bedside.</p> | |
| <p>"Rebecca and others like her must live with all the | |
| terrible complications that diabetes brings on, all the while | |
| taking insulin and pricking their fingers day in and day out just | |
| to stay alive," says Emily. "So when she asks if what | |
| I’m doing will help, it’s desperately important that | |
| I’m able to answer, ‘Yes.’"</p> | |
| <p>The new JDFI endeavor to "map" research quickly | |
| became a full-time concern for volunteer Sandra Puczynski. Her | |
| qualifications as an expert in the field made her an obvious | |
| choice — a doctorate in clinical research, experience as a | |
| diabetes educator, and membership on the JDFI Lay Review | |
| Committee. But add to those a passion, a dedication that springs | |
| from the fact that her 13-year-old daughter, Michelle, was | |
| diagnosed with diabetes before she reached her first birthday.</p> | |
| <p>"This is a complicated disease, and research dollars are | |
| limited," Sandra says. "Already, the ‘maps’ | |
| we have prepared are being studied by a task force drawn from the | |
| worlds of academia, industry, biotechnology, and the National | |
| Institutes of Health. The aims are to identify gaps and define | |
| new opportunities that are logical and have the highest | |
| likelihood of success. We believe it’s a priority-setting | |
| approach that will help us spend wisely to move science | |
| forward."</p> | |
| <p>Who can doubt that for Emily and Sandra, the search for a cure | |
| is personal? They bring to their roles a commitment that is | |
| common to all those who live with the disease. Such commitment is | |
| the foundation of JDFI’s success thus far, and the key to | |
| improving the quality of life for people with diabetes — | |
| today, tomorrow, and the day after.…</p> | |
| <p>Voices of professionalism blended with passion: the research | |
| scientists whose work JDFI believes — knows — will lead | |
| to the cure…As we prepare to take the lead in pushing | |
| research from bench to bedside, from the laboratory to the | |
| doctor’s office, our focus must intensify. We must identify | |
| the obstacles, the gaps in our knowledge which hold our progress | |
| back and seek to overcome them. We must choose the most likely | |
| paths to a cure for diabetes and its devastating complications, | |
| and speed our way down these paths.</p> | |
| <p>With us, along what we hope will be the last stage of our | |
| journey, will be our most important partners — our | |
| researchers. "When we began our search," says S. Robert | |
| Levine, M.D., a member of the JDFI Board, the Research Committee | |
| and Chair of the Government Relations Committee, "we knew | |
| very little about the causes and consequences of diabetes. But 27 | |
| years of research progress have added greatly to the diabetes | |
| knowledge base. We are now on the threshold of a cure, ready to | |
| move research advances from the laboratory bench to our loved | |
| ones’ bedsides."</p> | |
| <p>Dramatic clinical breakthroughs? They will come in beta cell | |
| replacement, preventing and treating complications, arresting the | |
| progress of the disease, as well as in early detection and | |
| disease prevention. </p> | |
| <p>The key to success in beta cell transplantation is to convince | |
| the body to accept foreign cells, according to Ali Naji, M.D., | |
| Ph.D., at the Hospital of the University of Pennsylvania. Dr. | |
| Naji, Chairman of JDFI’s Medical Science Review Committee | |
| and Medical Advisory Board, is one <br> | |
| of the researchers examining this problem. Some transplantation | |
| sites in the body are "privileged," that is, shielded | |
| from the immune system. One of these privileged sites, the | |
| thymus, is responsible for teaching cells in the immune system | |
| the difference between "self" and "non-self." | |
| Dr. Naji believes that if islet cells could be successfully | |
| implanted in the thymus in order for the immune system to | |
| recognize them as self, then they could be placed elsewhere in | |
| the body and not be attacked. In addition, the patient would not | |
| have to take immunosuppressant drugs, which can have adverse side | |
| effects.</p> | |
| <p>Already, scientific pioneers have returned with assurances | |
| that their efforts will bring real help to real people. Leonard | |
| Harrison, M.D., of the Royal Melbourne Hospital in Victoria, | |
| Australia, cites tremendous progress in immunology research that | |
| can lead to a number of areas of prevention. An example he points | |
| out has the potential for blocking the self-destructive immune | |
| response.</p> | |
| <p>"Insulin is the target of the auto-immune attack in | |
| diabetes," Harrison says. "We have found that if we | |
| deliver insulin back to an individual who is at risk for | |
| diabetes, it induces a protective immune response. The response | |
| in turn blocks the destructive immune response that is destroying | |
| the insulin-producing beta cells in the pancreas."</p> | |
| <p>"We have seen that tight control of blood sugar is very | |
| important to reduce or prevent complications," says Arthur | |
| Rubenstein, M.D., Department of Medicine, University of Chicago | |
| Hospital, "but complications still occur, despite control. | |
| So it is important that we introduce as fast as we can treatments | |
| to prevent and treat heart disease, kidney disease and eye | |
| disease. Already, there are new drugs in use or development that | |
| will forestall kidney disease and that will enhance nerve growth | |
| and stability. Beyond control and the treatment of complications, | |
| we have also seen dramatic advances toward the cure of diabetes | |
| through transplantation. There are many important avenues that | |
| should lead rapidly to improving the lives of people with | |
| diabetes."</p> | |
| <p>There is also hopeful news in the field of genetic research, | |
| this from John Todd, Ph.D., Professor of Human Genetics at Oxford | |
| University: "We are certain that a child who develops | |
| diabetes does so because of a genetic susceptibility," he | |
| says. "An unknown series of environmental factors triggers | |
| it. Now, we are beginning to pinpoint the susceptibility genes. | |
| As we assemble the genetic jigsaw, we will be able to work out | |
| ways to block their effect."</p> | |
| <p>For some 27 years now, JDFI has been uniquely successful in | |
| harnessing the discipline of science to our members’ | |
| passionate belief that a cure can — and will — be | |
| found. To speed the discovery of a cure, we ask that the | |
| scientists funded by the organization continue to share that | |
| passion.</p> | |
| <p>The passion of parents of children with diabetes extends | |
| beyond neighborhoods, beyond borders and boundaries…Today, | |
| JDFI is everywhere, united by its members’ single-minded | |
| quest for a cure. Bridging oceans and political boundaries, | |
| culture and languages, the organization takes strength from its | |
| ever-renewing commitment to the children and adults with | |
| diabetes.</p> | |
| <p>In Melbourne, Australia, Sue Alberti vividly recalls the day | |
| when a child in her family circle was diagnosed with diabetes. | |
| "It was July 13, 1982." The onset of the illness led to | |
| Sue’s present positions as a member of the JDFI Melbourne | |
| chapter and of the Australian board, and a member of the | |
| International Board. She was a 1997 recipient of the Order of | |
| Australia Medal.</p> | |
| <p>In Piedmont, North Carolina, Anne Hummel has a simple | |
| explanation for her decision to become a co-founder of the | |
| Piedmont Triad Chapter of JDFI: "I wanted to make my | |
| daughter’s life better," she says. Following the grim | |
| diagnosis for her 12-year-old, Anne found help at the other end | |
| of our information hotline, 1-800-JDF-CURE. Since then, she has | |
| helped build a dynamic chapter that provides much-needed funding | |
| to fuel the search for a cure.</p> | |
| <p>Buff Perry, co-founder of the Piedmont Triad Chapter, along | |
| with Anne, also speaks matter-of-factly about her decision to | |
| devote untold hours to the effort. "My daughter, who is 25, | |
| has had diabetes since the age of six," she says. "When | |
| she was small, I felt I was waiting for someone else to do | |
| something about the disease. Now I’m doing something about | |
| it."</p> | |
| <p>Across the Atlantic, in Liverpool, United Kingdom, Anne | |
| Burrows similarly acknowledges that "I realized I had to do | |
| something for myself and my daughters," and the | |
| "something" was to become involved with JDFI. | |
| Anne’s daughters, Emma and Lucy, who are now 20 and 13, | |
| respectively, developed diabetes before their first birthdays. | |
| Notes their mother: "The work of the Juvenile Diabetes | |
| Foundation International showed me that Emma and Lucy did have | |
| futures — ones that have been made brighter by | |
| research."</p> | |
| <p>In Toronto, where he serves as vice president of the JDFI | |
| Canada Board of Directors and president of the Toronto Chapter, | |
| Vince Brewerton relates that a routine annual physical led to the | |
| diagnosis of his own diabetes at age 33. The former management | |
| consultant considers himself fortunate in that "if I had to | |
| have diabetes, I’m lucky to have it now that research has | |
| made a lot of progress, and there’s more to come."</p> | |
| <p>In Portland, Oregon, attorney Katherine Cowan, whose | |
| six-year-old daughter was diagnosed with diabetes two years ago, | |
| is President of the Board of the Greater Portland Chapter. She | |
| says, "The appeal of the Juvenile Diabetes Foundation for me | |
| has been its focus on research. And our Government Relations work | |
| helps keep the research going."</p> | |
| <p>These and thousands of other people throughout the world are | |
| united by sharing the founders’ overriding vision of the | |
| role of the Juvenile Diabetes Foundation International.</p> | |
| <p>A cure, and nothing less.</p> | |
| <p>Speaking with a single voice, JDFI private and public partners | |
| produce progress in research that will end the search…No one | |
| needs to be told that the critical element in JDFI’s search | |
| for a cure is the wondrous combination of private and public | |
| partners who provide the dollars for research. Initially, many of | |
| the private individuals and government agencies who come to our | |
| cause might sign on for various reasons, but they stay for one | |
| reason alone: they want to help us find — or fund the search | |
| that finds — a cure.</p> | |
| <p>"Diabetes is the single largest chronic disease | |
| represented here at Carolina Healthcare System’s | |
| facilities," says CEO Harry Nurkin, Ph.D. "We’re | |
| committed to improving the long-term future of our patients, and | |
| diabetes is counter-productive to that goal.</p> | |
| <p>"A former chapter president pressed us into service to | |
| support a local Walk to Cure Diabetes," Nurkin says. | |
| "After a marathon round of meetings and pep rallies, I | |
| learned just how widespread diabetes is and how it affects | |
| families and friends."</p> | |
| <p>Likewise, David Vandewater, Chief Operations Officer of | |
| Columbia Healthcare Corp., fell into a Walk to Cure Diabetes | |
| commitment made by a departing executive. "The Juvenile | |
| Diabetes Foundation’s Nashville staff gave me all the | |
| information I needed," he says. "and made me feel | |
| completely at home. I didn’t think the Nashville target was | |
| enough of a stretch, so I raised it. Seven hundred employees | |
| walked last year."</p> | |
| <p>A friend whose granddaughter has diabetes asked Garnett Smith, | |
| President of Advance Auto Parts, to attend a Walk to Cure | |
| Diabetes campaign breakfast. He went along, and some of his | |
| employees went with him. "When we returned from the meeting | |
| and began to talk with other Advance employees, we found that | |
| many of them have a family connection to diabetes. One of our | |
| managers participated in the Walk with her daughter, who has | |
| diabetes. I walked with them, and the five miles carried an | |
| education with it."</p> | |
| <p>Before my involvement in the Walk, I had only a vague | |
| understanding of how devastating this disease is for children, | |
| and that every child is potentially at risk," says Lynn | |
| Horak, President of Norwest Bank of Iowa. "After we became | |
| involved, people began coming up to me saying, ‘my child has | |
| diabetes.’ Those people and their children are my customers | |
| and future customers, and I need to do what I can to help find a | |
| cure for the disease that controls their lives."</p> | |
| <p>In addition to our private partners, our public partners have | |
| worked with us to revolutionize a search for a cure. "The | |
| Juvenile Diabetes Foundation International did more than promote | |
| groundbreaking research when it established its The Only Remedy | |
| Is A Cure Campaign," says Sherry Benaroya, Campaign | |
| Co-chair. "It pioneered a unique partnership with | |
| government, leveraging private research dollars by stimulating | |
| increased spending by federal agencies."</p> | |
| <p>Today, the organization collaborates closely with four | |
| institutes of the U.S. National Institutes of Health, and has | |
| developed new relationships with the Department of Veterans | |
| Affairs and the Medical Research Councils of Canada and | |
| Australia. And throughout the world, the search for a cure has | |
| picked up speed as public partners join in melding public and | |
| private energies and dollars.</p> | |
| <p>"The bridge between the research bench and the | |
| patient’s bedside is the next major step toward a cure for | |
| diabetes," said Kenneth W. Kizer, M.D., M.P.H. Under | |
| Secretary for Health of the U.S. Department of Veterans Affairs, | |
| in an interview with Countdown Magazine, the diabetes research | |
| publication of JDFI. "We need to form a link to clinical | |
| practice, to bring hope and help to individuals with | |
| diabetes." He views the innovative public/private | |
| partnership between JDFI and the Department of Veterans Affairs | |
| as "a creative and effective way to enhance critical | |
| diabetes research efforts."</p> | |
| <p>Creative. Effective. These are the kind of words that an | |
| organization such as ours enjoys hearing, wants and needs to | |
| hear. But everyone who toils at JDFI, whether for a few moments | |
| or hours or through long days or longer years — and everyone | |
| who dreams at JDFI—is aware that such words can only be | |
| possible because of our private partners, who themselves keep two | |
| other words in mind: Personal commitment.</p> | |
| <p>These words, believed in by all of us, will help bring about | |
| the end to our search. They’ll help bring about a cure.</p> | |
| <p> </p> | |
| <p><a href="index.html">Return to Home Page</a></p> | |
| <hr> | |
| <table border="0"> | |
| <tr> | |
| <td align="center"><a href="about.htm"><img src="images/b-abt.gif" border="0" width="55" height="29"></a></td> | |
| <td align="center"><a href="info_pub.htm"><img src="images/b-pubs.gif" border="0" width="35" height="45"></a></td> | |
| <td align="center"><a href="chapters.htm"><img src="images/b-chaps.gif" border="0" width="40" height="40"></a></td> | |
| <td align="center"><a href="research.htm"><img src="images/b-res.gif" border="0" width="35" height="40"></a></td> | |
| <td align="center"><a href="govt_rel.htm"><img src="images/b-govt.gif" border="0" width="30" height="43"></a></td> | |
| <td align="center"><a href="walk.htm"><img src="images/b-walk.gif" border="0" width="64" height="25"></a></td> | |
| <td align="center"><a href="howhelp.htm"><img src="images/b-how.gif" border="0" width="35" height="40"></a></td> | |
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| <td align="center"> </td> | |
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| </tr> | |
| <tr> | |
| <td align="center" valign="top"><a href="about.htm"><font size="2">About JDF</font></a></td> | |
| <td align="center" valign="top"><a href="info_pub.htm"><font size="2">Diabetes<br> | |
| Information<br> | |
| &AMP Publications</font></a></td> | |
| <td align="center" valign="top"><a href="chapters.htm"><font size="2">Local<br> | |
| JDF<br> | |
| Chapters</font></a></td> | |
| <td align="center" valign="top"><a href="research.htm"><font size="2">Research</font></a></td> | |
| <td align="center" valign="top"><a href="govt_rel.htm"><font size="2">Government<br> | |
| Relations</font></a></td> | |
| <td align="center" valign="top"><a href="walk.htm"><font size="2">Walk for<br> | |
| the Cure</font></a></td> | |
| <td align="center" valign="top"><a href="howhelp.htm"><font size="2">How You<br> | |
| Can Help</font></a></td> | |
| <td align="center" valign="top"><a href="membersp.htm"><font size="2">Membership and<br> | |
| Its Benefits</font></a></td> | |
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| </table> | |
| <p><font size="2"><b>Copyright © 1996 Juvenile Diabetes | |
| Foundation International. ALL RIGHTS RESERVED.<br> | |
| The BETA SOCIETY, COUNTDOWN, CREATING A WORLD WITHOUT DIABETES, | |
| THE DIABETES RESEARCH FOUNDATION, JDF, JUVENILE DIABETES | |
| FOUNDATION INTERNATIONAL, THE ONLY REMEDY IS A CURE, WALK FOR THE | |
| CURE, 1-800-JDF-CURE and 1-800-WALK-JDF are Trademarks and | |
| Service marks of the Juvenile Diabetes Foundation International. </b><br> | |
| E-mail comments to </font><a href="mailto:info@jdfcure.com"><font size="2">info@jdfcure.com</font></a><font size="2"><br> | |
| Juvenile Diabetes Foundation<br> | |
| The Diabetes Research Foundation<br> | |
| 120 Wall Street<br> | |
| New York, NY 10005-4001<br> | |
| 800-JDF-CURE<br> | |
| 212-785-9500<br> | |
| Fax 212-785-9595</font><br> | |
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