diff --git a/packages/@aws-cdk/aws-cloudfront/lib/cache-policy.ts b/packages/@aws-cdk/aws-cloudfront/lib/cache-policy.ts
index e9dbf46901eda..a71569e89f02d 100644
--- a/packages/@aws-cdk/aws-cloudfront/lib/cache-policy.ts
+++ b/packages/@aws-cdk/aws-cloudfront/lib/cache-policy.ts
@@ -1,4 +1,4 @@
-import { Duration, Names, Resource, Token } from '@aws-cdk/core';
+import { Duration, Names, Resource, Stack, Token } from '@aws-cdk/core';
 import { Construct } from 'constructs';
 import { CfnCachePolicy } from './cloudfront.generated';
 
@@ -125,7 +125,7 @@ export class CachePolicy extends Resource implements ICachePolicy {
       physicalName: props.cachePolicyName,
     });
 
-    const cachePolicyName = props.cachePolicyName ?? Names.uniqueId(this);
+    const cachePolicyName = props.cachePolicyName ?? `${Names.uniqueId(this)}-${Stack.of(this).region}`;
     if (!Token.isUnresolved(cachePolicyName) && !cachePolicyName.match(/^[\w-]+$/i)) {
       throw new Error(`'cachePolicyName' can only include '-', '_', and alphanumeric characters, got: '${props.cachePolicyName}'`);
     }
diff --git a/packages/@aws-cdk/aws-cloudfront/test/cache-policy.test.ts b/packages/@aws-cdk/aws-cloudfront/test/cache-policy.test.ts
index 4f6d618c51621..07d2752de4e2c 100644
--- a/packages/@aws-cdk/aws-cloudfront/test/cache-policy.test.ts
+++ b/packages/@aws-cdk/aws-cloudfront/test/cache-policy.test.ts
@@ -24,7 +24,7 @@ describe('CachePolicy', () => {
 
     expect(stack).toHaveResource('AWS::CloudFront::CachePolicy', {
       CachePolicyConfig: {
-        Name: 'StackCachePolicy0D6FCBC0',
+        Name: 'StackCachePolicy0D6FCBC0-testregion',
         MinTTL: 0,
         DefaultTTL: 86400,
         MaxTTL: 31536000,