diff --git a/.githooks/pre-push b/.githooks/pre-push
index 719e35e88f..9235297add 100755
--- a/.githooks/pre-push
+++ b/.githooks/pre-push
@@ -12,5 +12,5 @@ start_time=`date +%s`
 tox -e sphinx,doc8 --parallel all
 ./ci-scripts/displaytime.sh 'sphinx,doc8' $start_time
 start_time=`date +%s`
-tox -e py36,py37,py38,py39 --parallel all -- tests/unit
-./ci-scripts/displaytime.sh 'py36,py37,py38,py39 unit' $start_time
+tox -e py37,py38,py39 --parallel all -- tests/unit
+./ci-scripts/displaytime.sh 'py37,py38,py39 unit' $start_time
diff --git a/README.rst b/README.rst
index ab62eddad0..44f724a781 100644
--- a/README.rst
+++ b/README.rst
@@ -87,7 +87,6 @@ Supported Python Versions
 
 SageMaker Python SDK is tested on:
 
-- Python 3.6
 - Python 3.7
 - Python 3.8
 - Python 3.9
diff --git a/requirements/extras/scipy_requirements.txt b/requirements/extras/scipy_requirements.txt
index 9136ba9f03..1cf073e9f5 100644
--- a/requirements/extras/scipy_requirements.txt
+++ b/requirements/extras/scipy_requirements.txt
@@ -1 +1 @@
-scipy==1.5.4
+scipy==1.7.2
diff --git a/setup.py b/setup.py
index 780cbaed04..75a113f019 100644
--- a/setup.py
+++ b/setup.py
@@ -91,7 +91,6 @@ def read_requirements(filename):
         "Natural Language :: English",
         "License :: OSI Approved :: Apache Software License",
         "Programming Language :: Python",
-        "Programming Language :: Python :: 3.6",
         "Programming Language :: Python :: 3.7",
         "Programming Language :: Python :: 3.8",
         "Programming Language :: Python :: 3.9",
diff --git a/tox.ini b/tox.ini
index 8822f897a2..47d23b0b89 100644
--- a/tox.ini
+++ b/tox.ini
@@ -4,7 +4,7 @@
 # and then run "tox" from this directory.
 
 [tox]
-envlist = black-format,flake8,pylint,docstyle,sphinx,doc8,twine,py36,py37,py38,py39
+envlist = black-format,flake8,pylint,docstyle,sphinx,doc8,twine,py37,py38,py39,py310
 
 skip_missing_interpreters = False
 
@@ -74,7 +74,7 @@ commands =
     {env:IGNORE_COVERAGE:} coverage report -i --fail-under=86
 deps = .[test]
 depends =
-    {py36,py37,py38,py39}: clean
+    {py37,py38,py39,py310}: clean
 
 [testenv:flake8]
 skipdist = true