diff --git a/src/sagemaker/jumpstart/region_config.json b/src/sagemaker/jumpstart/region_config.json
index fe5268e294..96209f9957 100644
--- a/src/sagemaker/jumpstart/region_config.json
+++ b/src/sagemaker/jumpstart/region_config.json
@@ -158,6 +158,22 @@
         "content_bucket": "jumpstart-cache-prod-us-gov-west-1",
         "gated_content_bucket": "jumpstart-private-cache-prod-us-gov-west-1"
     },
+    "us-iso-east-1": {
+        "content_bucket": "jumpstart-cache-prod-us-iso-east-1",
+        "gated_content_bucket": "jumpstart-private-cache-prod-us-iso-east-1"
+    },
+    "us-isob-east-1": {
+        "content_bucket": "jumpstart-cache-prod-us-isob-east-1",
+        "gated_content_bucket": "jumpstart-private-cache-prod-us-isob-east-1"
+    },
+    "us-isof-east-1": {
+        "content_bucket": "jumpstart-cache-prod-us-isof-east-1",
+        "gated_content_bucket": "jumpstart-private-cache-prod-us-isof-east-1"
+    },
+    "us-isof-south-1": {
+        "content_bucket": "jumpstart-cache-prod-us-isof-south-1",
+        "gated_content_bucket": "jumpstart-private-cache-prod-us-isof-south-1"
+    },
     "us-west-1": {
         "content_bucket": "jumpstart-cache-prod-us-west-1",
         "gated_content_bucket": "jumpstart-private-cache-prod-us-west-1",