diff --git a/packages/core/src/render3/instructions/shared.ts b/packages/core/src/render3/instructions/shared.ts
index 5d21b2ba90015..2c1cbd4b8c4fb 100644
--- a/packages/core/src/render3/instructions/shared.ts
+++ b/packages/core/src/render3/instructions/shared.ts
@@ -1463,8 +1463,8 @@ const LContainerArray: any = ((typeof ngDevMode === 'undefined' || ngDevMode) &&
 export function createLContainer(
     hostNative: RElement | RComment | LView, currentView: LView, native: RComment, tNode: TNode,
     isForViewContainerRef?: boolean): LContainer {
-  ngDevMode && assertDomNode(native);
   ngDevMode && assertLView(currentView);
+  ngDevMode && !isProceduralRenderer(currentView[RENDERER]) && assertDomNode(native);
   // https://jsperf.com/array-literal-vs-new-array-really
   const lContainer: LContainer = new (ngDevMode ? LContainerArray : Array)(
       hostNative,  // host native
diff --git a/packages/core/src/render3/node_manipulation.ts b/packages/core/src/render3/node_manipulation.ts
index 9497e6b4e9df3..5987eb4dd6f61 100644
--- a/packages/core/src/render3/node_manipulation.ts
+++ b/packages/core/src/render3/node_manipulation.ts
@@ -93,7 +93,7 @@ function applyToElementOrContainer(
       lNodeToHandle = lNodeToHandle[HOST] !;
     }
     const rNode: RNode = unwrapRNode(lNodeToHandle);
-    ngDevMode && assertDomNode(rNode);
+    ngDevMode && !isProceduralRenderer(renderer) && assertDomNode(rNode);
 
     if (action === WalkTNodeTreeAction.Create && parent !== null) {
       if (beforeNode == null) {
diff --git a/packages/core/src/render3/util/view_utils.ts b/packages/core/src/render3/util/view_utils.ts
index 02492b25944d8..8de1909721536 100644
--- a/packages/core/src/render3/util/view_utils.ts
+++ b/packages/core/src/render3/util/view_utils.ts
@@ -11,9 +11,9 @@ import {assertTNodeForLView} from '../assert';
 import {LContainer, TYPE} from '../interfaces/container';
 import {LContext, MONKEY_PATCH_KEY_NAME} from '../interfaces/context';
 import {TNode} from '../interfaces/node';
-import {RNode} from '../interfaces/renderer';
+import {RNode, isProceduralRenderer} from '../interfaces/renderer';
 import {isLContainer, isLView} from '../interfaces/type_checks';
-import {FLAGS, HEADER_OFFSET, HOST, LView, LViewFlags, PARENT, PREORDER_HOOK_FLAGS, TData, TVIEW} from '../interfaces/view';
+import {FLAGS, HEADER_OFFSET, HOST, LView, LViewFlags, PARENT, PREORDER_HOOK_FLAGS, RENDERER, TData, TVIEW} from '../interfaces/view';
 
 
 
@@ -93,7 +93,7 @@ export function getNativeByTNode(tNode: TNode, lView: LView): RNode {
   ngDevMode && assertTNodeForLView(tNode, lView);
   ngDevMode && assertDataInRange(lView, tNode.index);
   const node: RNode = unwrapRNode(lView[tNode.index]);
-  ngDevMode && assertDomNode(node);
+  ngDevMode && !isProceduralRenderer(lView[RENDERER]) && assertDomNode(node);
   return node;
 }
 
@@ -110,7 +110,7 @@ export function getNativeByTNodeOrNull(tNode: TNode, lView: LView): RNode|null {
   if (index !== -1) {
     ngDevMode && assertTNodeForLView(tNode, lView);
     const node: RNode|null = unwrapRNode(lView[index]);
-    ngDevMode && node !== null && assertDomNode(node);
+    ngDevMode && node !== null && !isProceduralRenderer(lView[RENDERER]) && assertDomNode(node);
     return node;
   }
   return null;
diff --git a/packages/core/test/acceptance/renderer_factory_spec.ts b/packages/core/test/acceptance/renderer_factory_spec.ts
index 5f55f4aabb1d5..324d08b5a7ebc 100644
--- a/packages/core/test/acceptance/renderer_factory_spec.ts
+++ b/packages/core/test/acceptance/renderer_factory_spec.ts
@@ -198,3 +198,49 @@ function getAnimationRendererFactory2(document: any): RendererFactory2 {
           document.body, new MockAnimationDriver(), new ɵNoopAnimationStyleNormalizer()),
       fakeNgZone);
 }
+
+describe('custom renderer', () => {
+  @Component({
+    selector: 'some-component',
+    template: `<div><span></span></div>`,
+  })
+  class SomeComponent {
+  }
+
+  /**
+   * Creates a patched renderer factory that creates elements with a shape different than DOM node
+   */
+  function createPatchedRendererFactory(document: any) {
+    let rendererFactory = getRendererFactory2(document);
+    const origCreateRenderer = rendererFactory.createRenderer;
+    rendererFactory.createRenderer = function(element: any, type: RendererType2|null) {
+      const renderer = origCreateRenderer.call(this, element, type);
+      renderer.appendChild = () => {};
+      renderer.createElement = (name: string) => ({
+        name,
+        el: document.createElement(name),
+      });
+      return renderer;
+    };
+
+    return rendererFactory;
+  }
+
+  beforeEach(() => {
+    TestBed.configureTestingModule({
+      declarations: [SomeComponent],
+      providers: [{
+        provide: RendererFactory2,
+        useFactory: (document: any) => createPatchedRendererFactory(document),
+        deps: [DOCUMENT]
+      }]
+    });
+  });
+
+  it('should not trigger errors', () => {
+    expect(() => {
+      const fixture = TestBed.createComponent(SomeComponent);
+      fixture.detectChanges();
+    }).not.toThrow();
+  });
+});
\ No newline at end of file