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Caveats
Just some things to keep in mind when using Babel.
/docs/usage/caveats/
/caveats.html

Polyfills

In order for certain features to work they require certain polyfills. You can satisfy all Babel feature requirements by using babel-polyfill.

You may alternatively/selectively include what you need:

Feature Requirements
Async functions, Generators regenerator runtime
Array destructuring, For Of Symbol, prototype[Symbol.iterator]
Spread Array.from

There is also the loose option for some of these plugins.

Classes

Built-in classes such as Date, Array, DOM etc cannot be properly subclassed due to limitations in ES5 (for the es2015-classes plugin). You can try to use babel-plugin-transform-builtin-extend based on Object.setPrototypeOf and Reflect.construct, but it also has some limitations.

ES5

Since Babel assumes that your code will run in an ES5 environment it uses ES5 functions. So if you're using an environment that has limited or no support for ES5 such as lower versions of IE then using babel-polyfill will add support for these methods.

Internet Explorer

Classes (10 and below)

If you're inheriting from a class then static properties are inherited from it via __proto__, this is widely supported but you may run into problems with much older browsers.

NOTE: __proto__ is not supported on IE <= 10 so static properties will not be inherited. See the protoToAssign for a possible work around.

For classes that have supers, the super class won't resolve correctly. You can get around this by enabling the loose option in the es2015-classes plugin.

Getters/setters (8 and below)

In IE8 Object.defineProperty can only be used on DOM objects. This is unfortunate as it's required to set getters and setters. Due to this if you plan on supporting IE8 or below then the usage of getters and setters isn't recommended.

Reference: MDN.

Modules

By default, when using modules with Babel a non-enumerable __esModule property is exported. This is done through the use of Object.defineProperty which is unsupported in IE8 and below. A workaround for this is to enable the loose option in your corresponding module plugin.