The methInheritSim package generates simulated multigenerational DMS datasets that are useful to evaluate the power and the false discovery rate of experiment design analysis, such as the methylInheritance methylInheritance package does. The multigenerational DMS datasets can also be used to compare the efficiency of different inheritance detection software.
If you use this package for a publication, we would ask you to cite the following:
Pascal Belleau, Astrid Deschênes, Marie-Pier Scott-Boyer, Romain Lambrot, Mathieu Dalvai, Sarah Kimmins, Janice Bailey, Arnaud Droit; Inferring and modeling inheritance of differentially methylated changes across multiple generations, Nucleic Acids Research, Volume 46, Issue 14, 21 August 2018, Pages e85. DOI: https://doi.org/10.1093/nar/gky362
methInheritSim is now an official package of Bioconductor. The current release can be directly downloaded from their website: Current release
The vignette of the methInheritSim package, which is a document that provides a task-oriented description of the package functionality, is available on Bioconductor website: methInheritSim vignette
Pascal Belleau, Astrid Deschênes and Arnaud Droit.
See Arnaud Droit Lab website.
This package and the underlying methInheritSim code are distributed under the Artistic license 2.0. You are free to use and redistribute this software.
For more information on Artistic 2.0 License see http://opensource.org/licenses/Artistic-2.0
If you have any bugs or feature requests, let us know.
Thanks!