Zenodo offers a way to search for files by their md5 hash.
See e.g.,
https://github.com/cboettig/contentid/blob/27d546cb8b6ea1900b7785977ad87bb0ea1da952/R/zenodo_registry.R
So, assuming that we'll calculate md5 hashes for related sha256 hashes, we can turn Zenodo into a Preston (content) remote.