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A tool for analyzing the transcription, processing and degradation rates of genes by 4sU-seq(the Metabolic Label 4-thiouridine) data and RNA-seq(RNA sequencing) data. It can not only recognize the transcriptional dynamic rate at the measurement time points,but also obtain continuous changes in transcriptional dynamics. More importantly,it is abl…

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README.md

Package: pulseTD

Type: Package

Author: XinWang

Maintainer: The package maintainer xindd_2014@163.com

Title: Identification of Transcriptional Dynamics using Pulse Models via 4su-Seq Data and RNA-Seq Data

Version: 0.1.0

Date: 2019-5-5

Description: A tool for analyzing the transcription, processing and degradation rates of genes by 4sU-seq(the Metabolic Label 4-thiouridine) data and RNA-seq(RNA sequencing) data. It can not only recognize the transcriptional dynamic rate at the measurement time points,but also obtain continuous changes in transcriptional dynamics. More importantly,it is able to predict the trend of mRNA(Mature RNA) transcription and expression changes in the future. In terms of performance, 'pulseTD' has good robustness and accuracy.

License: GPL-2

Encoding: UTF-8

Depends: R (>= 3.4.0)

Imports: AnnotationDbi,SummarizedExperiment,Rsamtools,Biobase,S4Vectors,methods,parallel,GenomicFeatures, ggplot2, grid, GenomicAlignments

URL: https://github.com/bioWzz/pulseTD_0.1.0

RoxygenNote: 6.1.1

Suggests: knitr, rmarkdown, TxDb.Hsapiens.UCSC.hg19.knownGene

VignetteBuilder: knitr

About

A tool for analyzing the transcription, processing and degradation rates of genes by 4sU-seq(the Metabolic Label 4-thiouridine) data and RNA-seq(RNA sequencing) data. It can not only recognize the transcriptional dynamic rate at the measurement time points,but also obtain continuous changes in transcriptional dynamics. More importantly,it is abl…

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