diff --git a/src/wallet/rpcdump.cpp b/src/wallet/rpcdump.cpp
index 5f0d88288f..7de12c3a94 100644
--- a/src/wallet/rpcdump.cpp
+++ b/src/wallet/rpcdump.cpp
@@ -1584,6 +1584,10 @@ static UniValue ProcessDescriptorImport(CWallet& wallet, const UniValue& data, c
             } else {
                 wallet.AddActiveScriptPubKeyMan(spk_manager->GetID(), *w_desc.descriptor->GetOutputType(), internal);
             }
+        } else {
+            if (w_desc.descriptor->GetOutputType()) {
+                wallet.DeactivateScriptPubKeyMan(spk_manager->GetID(), *w_desc.descriptor->GetOutputType(), internal);
+            }
         }
 
         result.pushKV("success", UniValue(true));
diff --git a/src/wallet/wallet.cpp b/src/wallet/wallet.cpp
index 5ae490d5cc..521708e69c 100644
--- a/src/wallet/wallet.cpp
+++ b/src/wallet/wallet.cpp
@@ -3171,6 +3171,23 @@ void CWallet::LoadActiveScriptPubKeyMan(uint256 id, OutputType type, bool intern
     NotifyCanGetAddressesChanged();
 }
 
+void CWallet::DeactivateScriptPubKeyMan(uint256 id, OutputType type, bool internal)
+{
+    auto spk_man = GetScriptPubKeyMan(type, internal);
+    if (spk_man != nullptr && spk_man->GetID() == id) {
+        WalletLogPrintf("Deactivate spkMan: id = %s, type = %d, internal = %d\n", id.ToString(), static_cast<int>(type), static_cast<int>(internal));
+        WalletBatch batch(GetDatabase());
+        if (!batch.EraseActiveScriptPubKeyMan(static_cast<uint8_t>(type), internal)) {
+            throw std::runtime_error(std::string(__func__) + ": erasing active ScriptPubKeyMan id failed");
+        }
+
+        auto& spk_mans = internal ? m_internal_spk_managers : m_external_spk_managers;
+        spk_mans[type] = nullptr;
+    }
+
+    NotifyCanGetAddressesChanged();
+}
+
 bool CWallet::IsLegacy() const
 {
     if (m_internal_spk_managers.count(OutputType::LEGACY) == 0) {
diff --git a/src/wallet/wallet.h b/src/wallet/wallet.h
index b63938c5f1..001b94047a 100644
--- a/src/wallet/wallet.h
+++ b/src/wallet/wallet.h
@@ -895,6 +895,12 @@ class CWallet final : public WalletStorage, public interfaces::Chain::Notificati
     //! @param[in] internal Whether this ScriptPubKeyMan provides change addresses
     void LoadActiveScriptPubKeyMan(uint256 id, OutputType type, bool internal);
 
+    //! Remove specified ScriptPubKeyMan from set of active SPK managers. Writes the change to the wallet file.
+    //! @param[in] id The unique id for the ScriptPubKeyMan
+    //! @param[in] type The OutputType this ScriptPubKeyMan provides addresses for
+    //! @param[in] internal Whether this ScriptPubKeyMan provides change addresses
+    void DeactivateScriptPubKeyMan(uint256 id, OutputType type, bool internal);
+
     //! Create new DescriptorScriptPubKeyMans and add them to the wallet
     void SetupDescriptorScriptPubKeyMans() EXCLUSIVE_LOCKS_REQUIRED(cs_wallet);
 
diff --git a/src/wallet/walletdb.cpp b/src/wallet/walletdb.cpp
index 24d5351945..203fca8dd6 100644
--- a/src/wallet/walletdb.cpp
+++ b/src/wallet/walletdb.cpp
@@ -209,6 +209,12 @@ bool WalletBatch::WriteActiveScriptPubKeyMan(uint8_t type, const uint256& id, bo
     return WriteIC(make_pair(key, type), id);
 }
 
+bool WalletBatch::EraseActiveScriptPubKeyMan(uint8_t type, bool internal)
+{
+    const std::string key{internal ? DBKeys::ACTIVEINTERNALSPK : DBKeys::ACTIVEEXTERNALSPK};
+    return EraseIC(make_pair(key, type));
+}
+
 bool WalletBatch::WriteDescriptorKey(const uint256& desc_id, const CPubKey& pubkey, const CPrivKey& privkey)
 {
     // hash pubkey/privkey to accelerate wallet load
diff --git a/src/wallet/walletdb.h b/src/wallet/walletdb.h
index e7b2d7d780..d740aaadb3 100644
--- a/src/wallet/walletdb.h
+++ b/src/wallet/walletdb.h
@@ -253,6 +253,7 @@ class WalletBatch
     bool EraseDestData(const std::string &address, const std::string &key);
 
     bool WriteActiveScriptPubKeyMan(uint8_t type, const uint256& id, bool internal);
+    bool EraseActiveScriptPubKeyMan(uint8_t type, bool internal);
 
     DBErrors LoadWallet(CWallet* pwallet);
     DBErrors FindWalletTx(std::vector<uint256>& vTxHash, std::list<CWalletTx>& vWtx);
diff --git a/test/functional/wallet_importdescriptors.py b/test/functional/wallet_importdescriptors.py
index adde375e54..262175c789 100755
--- a/test/functional/wallet_importdescriptors.py
+++ b/test/functional/wallet_importdescriptors.py
@@ -372,6 +372,21 @@ def run_test(self):
         address = w1.getrawchangeaddress('legacy')
         assert_equal(address, "mpA2Wh9dvZT7yfELq1UnrUmAoc5qCkMetg")
 
+        self.log.info('Check can deactivate active descriptor')
+        self.test_importdesc({'desc': descsum_create('pkh([12345678]' + xpub + '/*)'),
+                              'range': [0, 5],
+                              'active': False,
+                              'timestamp': 'now',
+                              'internal': True
+                              },
+                             success=True)
+        assert_raises_rpc_error(-4, 'This wallet has no available keys', w1.getrawchangeaddress, 'legacy')
+
+        self.log.info('Verify activation state is persistent')
+        w1.unloadwallet()
+        self.nodes[1].loadwallet('w1')
+        assert_raises_rpc_error(-4, 'This wallet has no available keys', w1.getrawchangeaddress, 'legacy')
+
         # # Test importing a descriptor containing a WIF private key
         wif_priv = "cTe1f5rdT8A8DFgVWTjyPwACsDPJM9ff4QngFxUixCSvvbg1x6sh"
         address = "2MuhcG52uHPknxDgmGPsV18jSHFBnnRgjPg"