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BEP 29: packets with unrecognized IDs #83
http://www.bittorrent.org/beps/bep_0029.html doesn't specify how one should handle packets whose connection ID is not known for us.
RST packets should be small, so there shouldn't be any amplification as long as you verify that you're responding to something that has the minimum plausible packet size and rate-limit them. Sure, there's reflections, but those are unavoidable and you get them with TCP or properly-crafted requests too.