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bjoelle
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updated XML and priors
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README.md

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@@ -145,7 +145,7 @@ The next set is to set up the substitution models for each alignments, found in
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> In the **Site Model** panel, set the **Gamma Category Count** to **4**.
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> Click on the arrow next to **JC69**, and select the **HKY** model.
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> Select the remaining three partitions (use **shift+click**).
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> Select `noncoding` and click **OK** to to clone the site model for the other three partitions from `noncoding`.
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> Select `noncoding` in the **Clone from** dropdown menu and click **OK** to to clone the site model for the other three partitions from `noncoding`.
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>
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The final substitution model configuration is shown in [Figure 6](#subst).
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### The parameter priors
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Most of the default parameter priors are reasonable, so we will not change them. However, the default prior for the mean clock rate is a uniform distribution from 0 to Infinity, which allows values which are too large for most datasets. A reasonable value for the global substitution rate of primates is on the order of {% eqinline 10^{-2} %} substitution/site/My, so we will set a exponential prior around this value.
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Most of the default parameter priors are reasonable, so we will not change them. However, the default prior for the mean clock rate is a gamma distribution with {% eqinline \alpha = 0.01 %} and {% eqinline \beta = 100 %}. This distribution is very wide and does not correspond to our actual knowldege about the substitution process. A reasonable value for the global substitution rate of primates is on the order of {% eqinline 10^{-2} %} substitution/site/My, so we will set a exponential prior around this value.
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> Use the dropdown menu on the right of **clockRate.c:primates** to select a **Exponential** distribution for this prior.
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> Click on the arrow left to **clockRate.c:primates** to open the detailed options. Set the **Mean** parameter to **0.01**.

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