diff --git a/.changes/1.16.49.json b/.changes/1.16.49.json
new file mode 100644
index 0000000000..d6cf7bef3b
--- /dev/null
+++ b/.changes/1.16.49.json
@@ -0,0 +1,12 @@
+[
+  {
+    "category": "``ce``", 
+    "description": "[``botocore``] Update ce client to latest version", 
+    "type": "api-change"
+  }, 
+  {
+    "category": "``application-autoscaling``", 
+    "description": "[``botocore``] Update application-autoscaling client to latest version", 
+    "type": "api-change"
+  }
+]
\ No newline at end of file
diff --git a/.changes/next-release/api-change-applicationautoscaling-34491.json b/.changes/next-release/api-change-applicationautoscaling-34491.json
deleted file mode 100644
index 912a372758..0000000000
--- a/.changes/next-release/api-change-applicationautoscaling-34491.json
+++ /dev/null
@@ -1,5 +0,0 @@
-{
-  "category": "``application-autoscaling``", 
-  "type": "api-change", 
-  "description": "[``botocore``] Update application-autoscaling client to latest version"
-}
diff --git a/.changes/next-release/api-change-ce-73253.json b/.changes/next-release/api-change-ce-73253.json
deleted file mode 100644
index dfb426a4f0..0000000000
--- a/.changes/next-release/api-change-ce-73253.json
+++ /dev/null
@@ -1,5 +0,0 @@
-{
-  "category": "``ce``", 
-  "type": "api-change", 
-  "description": "[``botocore``] Update ce client to latest version"
-}
diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 19499f10f3..5cb8178786 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -2,6 +2,13 @@
 CHANGELOG
 =========
 
+1.16.49
+=======
+
+* api-change:``ce``: [``botocore``] Update ce client to latest version
+* api-change:``application-autoscaling``: [``botocore``] Update application-autoscaling client to latest version
+
+
 1.16.48
 =======
 
diff --git a/boto3/__init__.py b/boto3/__init__.py
index a258f6cc6d..0d7319875c 100644
--- a/boto3/__init__.py
+++ b/boto3/__init__.py
@@ -18,7 +18,7 @@
 
 
 __author__ = 'Amazon Web Services'
-__version__ = '1.16.48'
+__version__ = '1.16.49'
 
 
 # The default Boto3 session; autoloaded when needed.
diff --git a/setup.cfg b/setup.cfg
index 30aada0b8d..98747a0d0d 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -3,6 +3,6 @@ universal = 1
 
 [metadata]
 requires-dist =
-    botocore>=1.19.48,<1.20.0
+    botocore>=1.19.49,<1.20.0
     jmespath>=0.7.1,<1.0.0
     s3transfer>=0.3.0,<0.4.0
diff --git a/setup.py b/setup.py
index ec2481b16c..4f271dc866 100644
--- a/setup.py
+++ b/setup.py
@@ -14,7 +14,7 @@
 
 
 requires = [
-    'botocore>=1.19.48,<1.20.0',
+    'botocore>=1.19.49,<1.20.0',
     'jmespath>=0.7.1,<1.0.0',
     's3transfer>=0.3.0,<0.4.0'
 ]