diff --git a/pyproject.toml b/pyproject.toml
index 100e428..a67e1aa 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -24,7 +24,6 @@ dependencies = [
     "brainglobe-utils >=0.2.7",
     "imio",
     "napari >=0.4.5",
-    "npe2",
     "numpy",
     "pandas[hdf5]",
     "qtpy",