#chr	pos(1-based)	ref	alt	aaref	aaalt	rs_dbSNP151	hg19_chr	hg19_pos(1-based)	hg18_chr	hg18_pos(1-based)	aapos	genename	Ensembl_geneid	Ensembl_transcriptid	Ensembl_proteinid	Uniprot_acc	Uniprot_entry	HGVSc_ANNOVAR	HGVSp_ANNOVAR	HGVSc_snpEff	HGVSp_snpEff	HGVSc_VEP	HGVSp_VEP	APPRIS	GENCODE_basic	TSL	VEP_canonical	cds_strand	refcodon	codonpos	codon_degeneracy	Ancestral_allele	AltaiNeandertal	Denisova	VindijiaNeandertal	SIFT_score	SIFT_converted_rankscore	SIFT_pred	SIFT4G_score	SIFT4G_converted_rankscore	SIFT4G_pred	Polyphen2_HDIV_score	Polyphen2_HDIV_rankscore	Polyphen2_HDIV_pred	Polyphen2_HVAR_score	Polyphen2_HVAR_rankscore	Polyphen2_HVAR_pred	LRT_score	LRT_converted_rankscore	LRT_pred	LRT_Omega	MutationTaster_score	MutationTaster_converted_rankscore	MutationTaster_pred	MutationTaster_model	MutationTaster_AAE	MutationAssessor_score	MutationAssessor_rankscore	MutationAssessor_pred	FATHMM_score	FATHMM_converted_rankscore	FATHMM_pred	PROVEAN_score	PROVEAN_converted_rankscore	PROVEAN_pred	VEST4_score	VEST4_rankscore	MetaSVM_score	MetaSVM_rankscore	MetaSVM_pred	MetaLR_score	MetaLR_rankscore	MetaLR_pred	Reliability_index	M-CAP_score	M-CAP_rankscore	M-CAP_pred	REVEL_score	REVEL_rankscore	MutPred_score	MutPred_rankscore	MutPred_protID	MutPred_AAchange	MutPred_Top5features	MVP_score	MVP_rankscore	MPC_score	MPC_rankscore	PrimateAI_score	PrimateAI_rankscore	PrimateAI_pred	DEOGEN2_score	DEOGEN2_rankscore	DEOGEN2_pred	BayesDel_addAF_score	BayesDel_addAF_rankscore	BayesDel_addAF_pred	BayesDel_noAF_score	BayesDel_noAF_rankscore	BayesDel_noAF_pred	ClinPred_score	ClinPred_rankscore	ClinPred_pred	LIST-S2_score	LIST-S2_rankscore	LIST-S2_pred	Aloft_Fraction_transcripts_affected	Aloft_prob_Tolerant	Aloft_prob_Recessive	Aloft_prob_Dominant	Aloft_pred	Aloft_Confidence	CADD_raw	CADD_raw_rankscore	CADD_phred	CADD_raw_hg19	CADD_raw_rankscore_hg19	CADD_phred_hg19	DANN_score	DANN_rankscore	fathmm-MKL_coding_score	fathmm-MKL_coding_rankscore	fathmm-MKL_coding_pred	fathmm-MKL_coding_group	fathmm-XF_coding_score	fathmm-XF_coding_rankscore	fathmm-XF_coding_pred	Eigen-raw_coding	Eigen-raw_coding_rankscore	Eigen-phred_coding	Eigen-PC-raw_coding	Eigen-PC-raw_coding_rankscore	Eigen-PC-phred_coding	GenoCanyon_score	GenoCanyon_rankscore	integrated_fitCons_score	integrated_fitCons_rankscore	integrated_confidence_value	GM12878_fitCons_score	GM12878_fitCons_rankscore	GM12878_confidence_value	H1-hESC_fitCons_score	H1-hESC_fitCons_rankscore	H1-hESC_confidence_value	HUVEC_fitCons_score	HUVEC_fitCons_rankscore	HUVEC_confidence_value	LINSIGHT	LINSIGHT_rankscore	GERP++_NR	GERP++_RS	GERP++_RS_rankscore	phyloP100way_vertebrate	phyloP100way_vertebrate_rankscore	phyloP30way_mammalian	phyloP30way_mammalian_rankscore	phyloP17way_primate	phyloP17way_primate_rankscore	phastCons100way_vertebrate	phastCons100way_vertebrate_rankscore	phastCons30way_mammalian	phastCons30way_mammalian_rankscore	phastCons17way_primate	phastCons17way_primate_rankscore	SiPhy_29way_pi	SiPhy_29way_logOdds	SiPhy_29way_logOdds_rankscore	bStatistic	bStatistic_converted_rankscore	1000Gp3_AC	1000Gp3_AF	1000Gp3_AFR_AC	1000Gp3_AFR_AF	1000Gp3_EUR_AC	1000Gp3_EUR_AF	1000Gp3_AMR_AC	1000Gp3_AMR_AF	1000Gp3_EAS_AC	1000Gp3_EAS_AF	1000Gp3_SAS_AC	1000Gp3_SAS_AF	TWINSUK_AC	TWINSUK_AF	ALSPAC_AC	ALSPAC_AF	UK10K_AC	UK10K_AF	ESP6500_AA_AC	ESP6500_AA_AF	ESP6500_EA_AC	ESP6500_EA_AF	ExAC_AC	ExAC_AF	ExAC_Adj_AC	ExAC_Adj_AF	ExAC_AFR_AC	ExAC_AFR_AF	ExAC_AMR_AC	ExAC_AMR_AF	ExAC_EAS_AC	ExAC_EAS_AF	ExAC_FIN_AC	ExAC_FIN_AF	ExAC_NFE_AC	ExAC_NFE_AF	ExAC_SAS_AC	ExAC_SAS_AF	ExAC_nonTCGA_AC	ExAC_nonTCGA_AF	ExAC_nonTCGA_Adj_AC	ExAC_nonTCGA_Adj_AF	ExAC_nonTCGA_AFR_AC	ExAC_nonTCGA_AFR_AF	ExAC_nonTCGA_AMR_AC	ExAC_nonTCGA_AMR_AF	ExAC_nonTCGA_EAS_AC	ExAC_nonTCGA_EAS_AF	ExAC_nonTCGA_FIN_AC	ExAC_nonTCGA_FIN_AF	ExAC_nonTCGA_NFE_AC	ExAC_nonTCGA_NFE_AF	ExAC_nonTCGA_SAS_AC	ExAC_nonTCGA_SAS_AF	ExAC_nonpsych_AC	ExAC_nonpsych_AF	ExAC_nonpsych_Adj_AC	ExAC_nonpsych_Adj_AF	ExAC_nonpsych_AFR_AC	ExAC_nonpsych_AFR_AF	ExAC_nonpsych_AMR_AC	ExAC_nonpsych_AMR_AF	ExAC_nonpsych_EAS_AC	ExAC_nonpsych_EAS_AF	ExAC_nonpsych_FIN_AC	ExAC_nonpsych_FIN_AF	ExAC_nonpsych_NFE_AC	ExAC_nonpsych_NFE_AF	ExAC_nonpsych_SAS_AC	ExAC_nonpsych_SAS_AF	gnomAD_exomes_flag	gnomAD_exomes_AC	gnomAD_exomes_AN	gnomAD_exomes_AF	gnomAD_exomes_nhomalt	gnomAD_exomes_AFR_AC	gnomAD_exomes_AFR_AN	gnomAD_exomes_AFR_AF	gnomAD_exomes_AFR_nhomalt	gnomAD_exomes_AMR_AC	gnomAD_exomes_AMR_AN	gnomAD_exomes_AMR_AF	gnomAD_exomes_AMR_nhomalt	gnomAD_exomes_ASJ_AC	gnomAD_exomes_ASJ_AN	gnomAD_exomes_ASJ_AF	gnomAD_exomes_ASJ_nhomalt	gnomAD_exomes_EAS_AC	gnomAD_exomes_EAS_AN	gnomAD_exomes_EAS_AF	gnomAD_exomes_EAS_nhomalt	gnomAD_exomes_FIN_AC	gnomAD_exomes_FIN_AN	gnomAD_exomes_FIN_AF	gnomAD_exomes_FIN_nhomalt	gnomAD_exomes_NFE_AC	gnomAD_exomes_NFE_AN	gnomAD_exomes_NFE_AF	gnomAD_exomes_NFE_nhomalt	gnomAD_exomes_SAS_AC	gnomAD_exomes_SAS_AN	gnomAD_exomes_SAS_AF	gnomAD_exomes_SAS_nhomalt	gnomAD_exomes_POPMAX_AC	gnomAD_exomes_POPMAX_AN	gnomAD_exomes_POPMAX_AF	gnomAD_exomes_POPMAX_nhomalt	gnomAD_exomes_controls_AC	gnomAD_exomes_controls_AN	gnomAD_exomes_controls_AF	gnomAD_exomes_controls_nhomalt	gnomAD_exomes_controls_AFR_AC	gnomAD_exomes_controls_AFR_AN	gnomAD_exomes_controls_AFR_AF	gnomAD_exomes_controls_AFR_nhomalt	gnomAD_exomes_controls_AMR_AC	gnomAD_exomes_controls_AMR_AN	gnomAD_exomes_controls_AMR_AF	gnomAD_exomes_controls_AMR_nhomalt	gnomAD_exomes_controls_ASJ_AC	gnomAD_exomes_controls_ASJ_AN	gnomAD_exomes_controls_ASJ_AF	gnomAD_exomes_controls_ASJ_nhomalt	gnomAD_exomes_controls_EAS_AC	gnomAD_exomes_controls_EAS_AN	gnomAD_exomes_controls_EAS_AF	gnomAD_exomes_controls_EAS_nhomalt	gnomAD_exomes_controls_FIN_AC	gnomAD_exomes_controls_FIN_AN	gnomAD_exomes_controls_FIN_AF	gnomAD_exomes_controls_FIN_nhomalt	gnomAD_exomes_controls_NFE_AC	gnomAD_exomes_controls_NFE_AN	gnomAD_exomes_controls_NFE_AF	gnomAD_exomes_controls_NFE_nhomalt	gnomAD_exomes_controls_SAS_AC	gnomAD_exomes_controls_SAS_AN	gnomAD_exomes_controls_SAS_AF	gnomAD_exomes_controls_SAS_nhomalt	gnomAD_exomes_controls_POPMAX_AC	gnomAD_exomes_controls_POPMAX_AN	gnomAD_exomes_controls_POPMAX_AF	gnomAD_exomes_controls_POPMAX_nhomalt	gnomAD_genomes_flag	gnomAD_genomes_AC	gnomAD_genomes_AN	gnomAD_genomes_AF	gnomAD_genomes_nhomalt	gnomAD_genomes_AFR_AC	gnomAD_genomes_AFR_AN	gnomAD_genomes_AFR_AF	gnomAD_genomes_AFR_nhomalt	gnomAD_genomes_AMR_AC	gnomAD_genomes_AMR_AN	gnomAD_genomes_AMR_AF	gnomAD_genomes_AMR_nhomalt	gnomAD_genomes_ASJ_AC	gnomAD_genomes_ASJ_AN	gnomAD_genomes_ASJ_AF	gnomAD_genomes_ASJ_nhomalt	gnomAD_genomes_EAS_AC	gnomAD_genomes_EAS_AN	gnomAD_genomes_EAS_AF	gnomAD_genomes_EAS_nhomalt	gnomAD_genomes_FIN_AC	gnomAD_genomes_FIN_AN	gnomAD_genomes_FIN_AF	gnomAD_genomes_FIN_nhomalt	gnomAD_genomes_NFE_AC	gnomAD_genomes_NFE_AN	gnomAD_genomes_NFE_AF	gnomAD_genomes_NFE_nhomalt	gnomAD_genomes_AMI_AC	gnomAD_genomes_AMI_AN	gnomAD_genomes_AMI_AF	gnomAD_genomes_AMI_nhomalt	gnomAD_genomes_SAS_AC	gnomAD_genomes_SAS_AN	gnomAD_genomes_SAS_AF	gnomAD_genomes_SAS_nhomalt	gnomAD_genomes_POPMAX_AC	gnomAD_genomes_POPMAX_AN	gnomAD_genomes_POPMAX_AF	gnomAD_genomes_POPMAX_nhomalt	clinvar_id	clinvar_clnsig	clinvar_trait	clinvar_review	clinvar_hgvs	clinvar_var_source	clinvar_MedGen_id	clinvar_OMIM_id	clinvar_Orphanet_id	Interpro_domain	GTEx_V8_gene	GTEx_V8_tissue	Geuvadis_eQTL_target_gene
1	1118283	C	T	T	I	.	1	1118283	1	1108146	315;315;242	TTLL10;TTLL10;TTLL10	ENSG00000162571;ENSG00000162571;ENSG00000162571	ENST00000379290;ENST00000379289;ENST00000379288	ENSP00000368592;ENSP00000368591;ENSP00000368590	Q6ZVT0;Q6ZVT0;Q6ZVT0-3	TTL10_HUMAN;TTL10_HUMAN;TTL10_HUMAN	c.944C>T;c.944C>T;c.725C>T	p.T315I;p.T315I;p.T242I	c.944C>T;c.944C>T;c.725C>T	p.Thr315Ile;p.Thr315Ile;p.Thr242Ile	c.944C>T;c.944C>T;c.725C>T	p.Thr315Ile;p.Thr315Ile;p.Thr242Ile	principal1;principal1;.	Y;Y;Y	1;2;1	YES;.;.	+;+;+	ACA;ACA;ACA	2;2;2	0;0;0	C	C/C	C/C	C/C	0.073;0.073;0.095	0.34800	T;T;T	0.003;0.003;0.003	0.76473	D;D;D	0.883;0.883;0.915	0.50599	P;P;P	0.718;0.718;0.596	0.54779	P;P;P	0.028967	0.25522	U	0.333758	0.746819;0.746819;0.746819	0.33884	D;D;D	simple_aae;simple_aae;simple_aae	T315I;T242I;T315I	1.48;1.48;.	0.37141	L;L;.	3.41;3.41;3.41	0.05574	T;T;T	-4.35;-4.35;-4.12	0.76900	D;D;D	0.681;0.682;0.648	0.68863	-0.9964	0.30919	T	0.0245	0.10464	T	10	0.007729	0.20510	T	0.121	0.34042	0.529	0.63547	Q6ZVT0	T315I	Gain of ubiquitination at K313 (P = 0.1884); Loss of disorder (P = 0.255); Gain of glycosylation at K313 (P = 0.3578); Loss of helix (P = 0.3949); Gain of MoRF binding (P = 0.4151)	0.370789594751;0.370789594751;0.370789594751	0.36692	0.207176408666;.;.	0.23165	0.543806016445	0.44983	T	0.005963;0.005963;.	0.05402	T;T;.	-0.18413	0.23124	T	-0.502266	0.22112	T	0.855398237705231	0.50637	D	.;0.863614;0.864914	0.56300	.;D;D	.;.;.	.;.;.	.;.;.	.;.;.	.;.;.	.;.;.	2.643797	0.44380	22.7	2.620953	0.46382	22.8	0.98342319395843136	0.40457	0.85560	0.44705	D	AEFDBCIJ	0.256011	0.37502	N	-0.140134618962495	0.35655	2.050812	-0.178999282302932	0.32311	1.836925	0.999172948980321	0.38651	0.580535	0.33130	0	0.59043	0.45803	0	0.576033	0.28219	0	0.562822	0.20929	0	.	.	3.56	2.64	0.30504	1.503000	0.35323	0.112000	0.17000	-0.255000	0.07062	0.100000	0.22794	0.482000	0.26977	0.416000	0.27139	0.2332:0.7668:0.0:0.0	8.4249	0.31884	789	0.46346	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.;.;.	.	.	.