multiple samples support or GVCF support for mutect2 tumor-only mode

[wangyugui]

Hi.

We need multiple samples support or GVCF support for mutect2 tumor-only mode.

so we can diff the ./. and 0/0 in multiple normal samples.

There is neither multiple samples support nor GVCF support in version 4.0.2.1.

Best Regards

[davidbenjamin]

@wangyugui Could you explain your use case a bit further?

[wangyugui]

for example,
the var of sample Normal_A:
chr1 100 T A 1/1
chr1 110 T T 0/0(not ouputted in vcf)

the var of samlpe Normal_B:
chr1 100 T T ./. (not coveraged, not outputed in vcf too)
chr1 110 T A 1/1

[davidbenjamin]

@wangyugui I am leaning toward doing this in several months

[davidbenjamin]

@wangyugui We have decided to do this -- see #4887.