Update README.md #105

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+### Content overview
+
This directory contains WDL scripts developed at the Broad Institute and supported by the DSDE group (which develops GATK, Picard and Cromwell/WDL among other things). These scripts are NOT run in production at Broad; for production pipeline scripts, see the `broad_pipelines` directory.
When these scripts get updated, old versions are stored in the `archive` directory. Versions are distinguished with a datestamp (format: YYMMDD). Each WDL script is accompanied by a JSON file of example inputs bearing the same name, with the `.inputs.json` extension instead of `.wdl`. Unless otherwise specified, all WDL scripts can be run with the generic options file `generic.options.json`.
+### Important limitations
+
+These scripts are provided "as-is", without any guarantees as to performance
+or results. It is the responsibility of the user to test these scripts
+fully before running them in production.
+
+Many parameters and implementation decisions are optimized for our use of
+the Google Cloud Platform. In some cases (such as dynamic filename modifications and extension swapping using the sub() function) the scripts may need to be
+modified in order to be run successfully on a different platform.
@@ -1,11 +1,26 @@
+### Content overview
+
This directory contains the following WDL scripts used in production at
the Broad Institute. Old versions are stored in the `archive` directory.
Versions are distinguished with a datestamp (format: YYMMDD). Each WDL
script is accompanied by a JSON file of example inputs bearing the same
name, with the `.inputs.json` extension instead of `.wdl`, as well as a
JSON file of example options with the `.options.json` extension.
-####`PublicPairedSingleSampleWf-<datestamp>.wdl`
+### Important limitations
+
+These scripts are provided "as-is", without any guarantees as to performance
+or results. It is the responsibility of the user to test these scripts
+fully before running them in production.
+
+Many parameters and implementation decisions are optimized for our use of
+the Google Cloud Platform. In some cases (such as dynamic filename modifications
+and extension swapping using the sub() function) the scripts may need to be
+modified in order to be run successfully on a different platform.
+
+### Inventory of scripts
+
+#### `PublicPairedSingleSampleWf-<datestamp>.wdl`
This WDL pipeline implements data pre-processing and initial variant
calling (GVCF generation) according to the GATK Best Practices for
germline SNP and Indel discovery in human whole-genome sequencing (WGS)