diff --git a/core/iwasm/common/wasm_c_api.c b/core/iwasm/common/wasm_c_api.c
index 594d1ed962..ff88fae50b 100644
--- a/core/iwasm/common/wasm_c_api.c
+++ b/core/iwasm/common/wasm_c_api.c
@@ -299,6 +299,7 @@ wasm_config_new(void)
 
     memset(config, 0, sizeof(wasm_config_t));
     config->mem_alloc_type = Alloc_With_System_Allocator;
+
     return config;
 }
 
@@ -334,6 +335,16 @@ wasm_config_set_linux_perf_opt(wasm_config_t *config, bool enable)
     return config;
 }
 
+wasm_config_t *
+wasm_config_set_segue_flags(wasm_config_t *config, uint32 segue_flags)
+{
+    if (!config)
+        return NULL;
+
+    config->segue_flags = segue_flags;
+    return config;
+}
+
 static void
 wasm_engine_delete_internal(wasm_engine_t *engine)
 {
@@ -380,8 +391,8 @@ wasm_engine_new_internal(wasm_config_t *config)
     init_args.mem_alloc_type = config->mem_alloc_type;
     memcpy(&init_args.mem_alloc_option, &config->mem_alloc_option,
            sizeof(MemAllocOption));
-
     init_args.enable_linux_perf = config->enable_linux_perf;
+    init_args.segue_flags = config->segue_flags;
 
     if (!wasm_runtime_full_init(&init_args)) {
         LOG_DEBUG("wasm_runtime_full_init failed");
diff --git a/core/iwasm/common/wasm_runtime_common.h b/core/iwasm/common/wasm_runtime_common.h
index 64162a3f89..b113ec0d7f 100644
--- a/core/iwasm/common/wasm_runtime_common.h
+++ b/core/iwasm/common/wasm_runtime_common.h
@@ -438,7 +438,7 @@ typedef struct wasm_frame_t {
     const char *func_name_wp;
 } WASMCApiFrame;
 
-#ifdef WASM_ENABLE_JIT
+#if WASM_ENABLE_JIT != 0
 typedef struct LLVMJITOptions {
     uint32 opt_level;
     uint32 size_level;
diff --git a/core/iwasm/include/wasm_c_api.h b/core/iwasm/include/wasm_c_api.h
index 2bd17bf368..d13a712c45 100644
--- a/core/iwasm/include/wasm_c_api.h
+++ b/core/iwasm/include/wasm_c_api.h
@@ -181,6 +181,7 @@ typedef union MemAllocOption {
 struct wasm_config_t {
     mem_alloc_type_t mem_alloc_type;
     MemAllocOption mem_alloc_option;
+    uint32_t segue_flags;
     bool enable_linux_perf;
     /*TODO: wasi args*/
 };
@@ -200,6 +201,17 @@ wasm_config_set_mem_alloc_opt(wasm_config_t *, mem_alloc_type_t, MemAllocOption
 WASM_API_EXTERN own wasm_config_t*
 wasm_config_set_linux_perf_opt(wasm_config_t *, bool);
 
+/**
+ * Enable using GS register as the base address of linear memory in linux x86_64,
+ * which may speedup the linear memory access for LLVM AOT/JIT:
+ *   bit0 to bit4 denotes i32.load, i64.load, f32.load, f64.load, v128.load
+ *   bit8 to bit12 denotes i32.store, i64.store, f32.store, f64.store, v128.store
+ * For example, 0x01 enables i32.load, 0x0100 enables i32.store.
+ * To enable all load/store operations, use 0x1F1F
+ */
+WASM_API_EXTERN wasm_config_t*
+wasm_config_set_segue_flags(wasm_config_t *config, uint32_t segue_flags);
+
 // Engine
 
 WASM_DECLARE_OWN(engine)