Multifilament half-sarcomere model
Python
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multifil
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README.md

multifil - a simulation of a half sarcomere

To install, in the top level directory of a local copy of this repository:

  • run pip install -e . to install a symlinked copy that can be updated with a git pull
  • or run pip install . to install a local copy that isn't symlinked. I recommend the former as this model is in heavy flux and so you'll probably want recent changes directly from the repo.

Starting a run

The simplest run would be:

import multifil
sarc = multifil.hs.hs()
axial_force = sarc.run()

More complicated runs (workloops, length-velocity calculations) require the modification of sarcomere parameters such as z-line-to-m-line distance and Calcium activation during the run. This is managed by the aws.run.py module through the reading of JSON formatted meta files. The metafiles are specified in the same.