diff --git a/testing/buildbot/chromium.chromiumos.json b/testing/buildbot/chromium.chromiumos.json
index 0ab17fa4d04565..fd4d0567ac3a6f 100644
--- a/testing/buildbot/chromium.chromiumos.json
+++ b/testing/buildbot/chromium.chromiumos.json
@@ -5875,9 +5875,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.filter;../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -5889,8 +5889,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -6041,9 +6041,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -6055,8 +6055,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -6192,9 +6192,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -6206,8 +6206,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
diff --git a/testing/buildbot/chromium.fyi.json b/testing/buildbot/chromium.fyi.json
index 9eac1ff905ccf5..43de1ce2af11f0 100644
--- a/testing/buildbot/chromium.fyi.json
+++ b/testing/buildbot/chromium.fyi.json
@@ -88165,9 +88165,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.filter;../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -88179,8 +88179,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "service_account": "chromium-tester@chops-service-accounts.iam.gserviceaccount.com",
@@ -88301,9 +88301,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -88315,8 +88315,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "service_account": "chromium-tester@chops-service-accounts.iam.gserviceaccount.com"
@@ -88427,9 +88427,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -88441,8 +88441,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "service_account": "chromium-tester@chops-service-accounts.iam.gserviceaccount.com",
@@ -89782,9 +89782,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.filter;../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -89795,8 +89795,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -89948,9 +89948,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -89961,8 +89961,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -90099,9 +90099,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -90112,8 +90112,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -91634,9 +91634,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.filter;../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -91647,8 +91647,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -91800,9 +91800,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -91813,8 +91813,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -91951,9 +91951,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -91964,8 +91964,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -92763,9 +92763,9 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.filter;../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome"
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "merge": {
           "args": [],
           "script": "//testing/merge_scripts/standard_gtest_merge.py"
@@ -92776,8 +92776,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
diff --git a/testing/buildbot/chromium.memory.json b/testing/buildbot/chromium.memory.json
index 09c03c6f5610ec..58b8c9c89bfa7c 100644
--- a/testing/buildbot/chromium.memory.json
+++ b/testing/buildbot/chromium.memory.json
@@ -18562,10 +18562,10 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.filter;../../testing/buildbot/filters/linux-lacros.interactive_ui_tests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome",
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome",
           "--test-launcher-print-test-stdio=always"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -18577,8 +18577,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -18736,10 +18736,10 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome",
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome",
           "--test-launcher-print-test-stdio=always"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -18751,8 +18751,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
@@ -18892,10 +18892,10 @@
       {
         "args": [
           "--test-launcher-filter-file=../../testing/buildbot/filters/linux-lacros.lacros_chrome_browsertests.skew.filter",
-          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome",
+          "--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome",
           "--test-launcher-print-test-stdio=always"
         ],
-        "description": "Run with ash-chrome version 110.0.5419.0",
+        "description": "Run with ash-chrome version 110.0.5421.0",
         "isolate_profile_data": true,
         "merge": {
           "args": [],
@@ -18907,8 +18907,8 @@
           "cipd_packages": [
             {
               "cipd_package": "chromium/testing/linux-ash-chromium/x86_64/ash.zip",
-              "location": "lacros_version_skew_tests_v110.0.5419.0",
-              "revision": "version:110.0.5419.0"
+              "location": "lacros_version_skew_tests_v110.0.5421.0",
+              "revision": "version:110.0.5421.0"
             }
           ],
           "dimension_sets": [
diff --git a/testing/buildbot/variants.pyl b/testing/buildbot/variants.pyl
index c7c8009c47c423..6c5b3cfee07925 100644
--- a/testing/buildbot/variants.pyl
+++ b/testing/buildbot/variants.pyl
@@ -22,16 +22,16 @@
   },
   'LACROS_VERSION_SKEW_CANARY': {
     'args': [
-      '--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5419.0/test_ash_chrome',
+      '--ash-chrome-path-override=../../lacros_version_skew_tests_v110.0.5421.0/test_ash_chrome',
     ],
-    'description': 'Run with ash-chrome version 110.0.5419.0',
+    'description': 'Run with ash-chrome version 110.0.5421.0',
     'identifier': 'Lacros version skew testing ash canary',
     'swarming': {
       'cipd_packages': [
         {
           'cipd_package': 'chromium/testing/linux-ash-chromium/x86_64/ash.zip',
-          'location': 'lacros_version_skew_tests_v110.0.5419.0',
-          'revision': 'version:110.0.5419.0',
+          'location': 'lacros_version_skew_tests_v110.0.5421.0',
+          'revision': 'version:110.0.5421.0',
         },
       ],
     },