diff --git a/docs/errors.md b/docs/errors.md
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index 0000000..ebfe698
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+++ b/docs/errors.md
@@ -0,0 +1,192 @@
+# Errors
+
+Similar to the familiar "404 Not Found" and "500 Internal Server Error" status codes in HTTP, Connect uses a set of [16 error codes](https://connectrpc.com/docs/protocol#error-codes). These error codes are designed to work consistently across Connect, gRPC, and gRPC-Web protocols.
+
+## Working with errors
+
+Connect handlers raise errors using `ConnectError`:
+
+=== "ASGI"
+
+    ```python
+    from connectrpc.code import Code
+    from connectrpc.errors import ConnectError
+    from connectrpc.request import RequestContext
+
+    async def greet(self, request: GreetRequest, ctx: RequestContext) -> GreetResponse:
+        if not request.name:
+            raise ConnectError(Code.INVALID_ARGUMENT, "name is required")
+        return GreetResponse(greeting=f"Hello, {request.name}!")
+    ```
+
+=== "WSGI"
+
+    ```python
+    from connectrpc.code import Code
+    from connectrpc.errors import ConnectError
+    from connectrpc.request import RequestContext
+
+    def greet(self, request: GreetRequest, ctx: RequestContext) -> GreetResponse:
+        if not request.name:
+            raise ConnectError(Code.INVALID_ARGUMENT, "name is required")
+        return GreetResponse(greeting=f"Hello, {request.name}!")
+    ```
+
+Clients catch errors the same way:
+
+=== "Async"
+
+    ```python
+    from connectrpc.code import Code
+    from connectrpc.errors import ConnectError
+
+    async with GreetServiceClient("http://localhost:8000") as client:
+        try:
+            response = await client.greet(GreetRequest(name=""))
+        except ConnectError as e:
+            if e.code == Code.INVALID_ARGUMENT:
+                print(f"Invalid request: {e.message}")
+            else:
+                print(f"RPC failed: {e.code} - {e.message}")
+    ```
+
+=== "Sync"
+
+    ```python
+    from connectrpc.code import Code
+    from connectrpc.errors import ConnectError
+
+    with GreetServiceClientSync("http://localhost:8000") as client:
+        try:
+            response = client.greet(GreetRequest(name=""))
+        except ConnectError as e:
+            if e.code == Code.INVALID_ARGUMENT:
+                print(f"Invalid request: {e.message}")
+            else:
+                print(f"RPC failed: {e.code} - {e.message}")
+    ```
+
+## Error codes
+
+Connect uses a set of [16 error codes](https://connectrpc.com/docs/protocol#error-codes). The `code` property of a `ConnectError` holds one of these codes. All error codes are available through the `Code` enumeration:
+
+```python
+from connectrpc.code import Code
+
+code = Code.INVALID_ARGUMENT
+code.value  # "invalid_argument"
+
+# Access by name
+Code["INVALID_ARGUMENT"]  # Code.INVALID_ARGUMENT
+```
+
+## Error messages
+
+The `message` property contains a descriptive error message. In most cases, the message is provided by the backend implementing the service:
+
+```python
+try:
+    response = await client.greet(GreetRequest(name=""))
+except ConnectError as e:
+    print(e.message)  # "name is required"
+```
+
+## Error details
+
+Errors can include strongly-typed details using protobuf messages:
+
+```python
+from connectrpc.code import Code
+from connectrpc.errors import ConnectError
+from connectrpc.request import RequestContext
+from google.protobuf.struct_pb2 import Struct, Value
+
+async def create_user(self, request: CreateUserRequest, ctx: RequestContext) -> CreateUserResponse:
+    if not request.email:
+        error_detail = Struct(fields={
+            "field": Value(string_value="email"),
+            "issue": Value(string_value="Email is required")
+        })
+
+        raise ConnectError(
+            Code.INVALID_ARGUMENT,
+            "Invalid user request",
+            details=[error_detail]
+        )
+    # ... rest of implementation
+```
+
+### Reading error details on the client
+
+Error details are `google.protobuf.Any` messages that can be unpacked to their original types:
+
+```python
+try:
+    response = await client.some_method(request)
+except ConnectError as e:
+    for detail in e.details:
+        # Check the type before unpacking
+        if detail.Is(Struct.DESCRIPTOR):
+            unpacked = Struct()
+            detail.Unpack(unpacked)
+            print(f"Error detail: {unpacked}")
+```
+
+### Standard error detail types
+
+With `googleapis-common-protos` installed, you can use standard types like:
+
+- `BadRequest`: Field violations in a request
+- `RetryInfo`: When to retry
+- `Help`: Links to documentation
+- `QuotaFailure`: Quota violations
+- `ErrorInfo`: Structured error metadata
+
+Example:
+
+```python
+from google.rpc.error_details_pb2 import BadRequest
+
+bad_request = BadRequest()
+violation = bad_request.field_violations.add()
+violation.field = "email"
+violation.description = "Must be a valid email address"
+
+raise ConnectError(
+    Code.INVALID_ARGUMENT,
+    "Invalid email format",
+    details=[bad_request]
+)
+```
+
+## HTTP representation
+
+In the Connect protocol, errors are always JSON:
+
+```http
+HTTP/1.1 400 Bad Request
+Content-Type: application/json
+
+{
+  "code": "invalid_argument",
+  "message": "name is required",
+  "details": [
+    {
+      "type": "google.protobuf.Struct",
+      "value": "base64-encoded-protobuf"
+    }
+  ]
+}
+```
+
+The `details` array contains error detail messages, where each entry has:
+
+- `type`: The fully-qualified protobuf message type (e.g., `google.protobuf.Struct`)
+- `value`: The protobuf message serialized in binary format and then base64-encoded
+
+## See also
+
+- [Interceptors](interceptors.md) for error transformation and logging
+- [Streaming](streaming.md) for stream-specific error handling
+- [Headers and trailers](headers-and-trailers.md) for attaching metadata to errors
+- [Usage guide](usage.md) for error handling best practices
diff --git a/docs/usage.md b/docs/usage.md
index ed683b6..969c3a6 100644
--- a/docs/usage.md
+++ b/docs/usage.md
@@ -159,3 +159,152 @@ class ElizaServiceImpl:
         for message in request:
             yield eliza_pb2.ConverseResponse(sentence=f"You said: {message.sentence}")
 ```
+
+## Error Handling Best Practices
+
+### Choosing appropriate error codes
+
+Select error codes that accurately reflect the situation:
+
+- Use `INVALID_ARGUMENT` for malformed requests that should never be retried
+- Use `FAILED_PRECONDITION` for requests that might succeed if the system state changes
+- Use `UNAVAILABLE` for transient failures that should be retried
+- Use `INTERNAL` sparingly - it indicates a bug in your code
+
+For more detailed guidance on choosing error codes, see the [Connect protocol documentation](https://connectrpc.com/docs/protocol#error-codes).
+
+### Providing helpful error messages
+
+Error messages should help the caller understand what went wrong and how to fix it:
+
+```python
+# Good - specific and actionable
+raise ConnectError(Code.INVALID_ARGUMENT, "email must contain an @ symbol")
+
+# Less helpful - too vague
+raise ConnectError(Code.INVALID_ARGUMENT, "invalid input")
+```
+
+### Using error details for structured data
+
+Rather than encoding structured information in error messages, use typed error details. For example:
+
+```python
+from google.rpc.error_details_pb2 import BadRequest
+
+# Good - structured details
+bad_request = BadRequest()
+for field, error in validation_errors.items():
+    violation = bad_request.field_violations.add()
+    violation.field = field
+    violation.description = error
+raise ConnectError(Code.INVALID_ARGUMENT, "Validation failed", details=[bad_request])
+
+# Less structured - information in message
+raise ConnectError(
+    Code.INVALID_ARGUMENT,
+    f"Validation failed: email: {email_error}, name: {name_error}"
+)
+```
+
+**Note**: While error details provide structured error information, they require client-side deserialization to be fully useful for debugging. Make sure to document expected error detail types in your API documentation to help consumers properly handle them.
+
+### Security considerations
+
+Avoid including sensitive data in error messages or details that will be sent to clients. For example:
+
+```python
+# Bad - leaks internal details
+raise ConnectError(Code.INTERNAL, f"Database query failed: {sql_query}")
+
+# Good - generic message
+raise ConnectError(Code.INTERNAL, "Failed to complete request")
+```
+
+### Handling timeouts
+
+Client timeouts are represented with `Code.DEADLINE_EXCEEDED`:
+
+```python
+from connectrpc.code import Code
+from connectrpc.errors import ConnectError
+
+async with GreetServiceClient("http://localhost:8000") as client:
+    try:
+        response = await client.greet(GreetRequest(name="World"), timeout_ms=1000)
+    except ConnectError as e:
+        if e.code == Code.DEADLINE_EXCEEDED:
+            print("Operation timed out")
+```
+
+### Implementing retry logic
+
+Some errors are retriable. Use appropriate error codes to signal this. Here's an example implementation:
+
+```python
+import asyncio
+from connectrpc.code import Code
+from connectrpc.errors import ConnectError
+
+async def call_with_retry(client, request, max_attempts=3):
+    """Retry logic for transient failures."""
+    for attempt in range(max_attempts):
+        try:
+            return await client.greet(request)
+        except ConnectError as e:
+            # Only retry transient errors
+            if e.code == Code.UNAVAILABLE and attempt < max_attempts - 1:
+                await asyncio.sleep(2 ** attempt)  # Exponential backoff
+                continue
+            raise
+```
+
+### Error transformation in interceptors
+
+Interceptors can catch and transform errors. This is useful for adding context, converting error types, or implementing retry logic. For example:
+
+=== "ASGI"
+
+    ```python
+    from connectrpc.code import Code
+    from connectrpc.errors import ConnectError
+
+    class ErrorLoggingInterceptor:
+        async def intercept_unary(self, call_next, request, ctx):
+            try:
+                return await call_next(request, ctx)
+            except ConnectError as e:
+                # Log the error with context
+                method = ctx.method()
+                print(f"Error in {method.service_name}/{method.name}: {e.code} - {e.message}")
+                # Re-raise the error
+                raise
+            except Exception as e:
+                # Convert unexpected errors to ConnectError
+                method = ctx.method()
+                print(f"Unexpected error in {method.service_name}/{method.name}: {e}")
+                raise ConnectError(Code.INTERNAL, "An unexpected error occurred")
+    ```
+
+=== "WSGI"
+
+    ```python
+    from connectrpc.code import Code
+    from connectrpc.errors import ConnectError
+
+    class ErrorLoggingInterceptor:
+        def intercept_unary_sync(self, call_next, request, ctx):
+            try:
+                return call_next(request, ctx)
+            except ConnectError as e:
+                # Log the error with context
+                method = ctx.method()
+                print(f"Error in {method.service_name}/{method.name}: {e.code} - {e.message}")
+                # Re-raise the error
+                raise
+            except Exception as e:
+                # Convert unexpected errors to ConnectError
+                method = ctx.method()
+                print(f"Unexpected error in {method.service_name}/{method.name}: {e}")
+                raise ConnectError(Code.INTERNAL, "An unexpected error occurred")
+    ```