diff --git a/trytond/trytond/application.py b/trytond/trytond/application.py
index e28500e91bd..1f68a409cf4 100644
--- a/trytond/trytond/application.py
+++ b/trytond/trytond/application.py
@@ -5,6 +5,8 @@
 import logging.config
 import os
 import threading
+import datetime
+import uwsgidecorators
 from io import StringIO
 
 __all__ = ['app', 'application']
@@ -36,11 +38,13 @@
 Pool.start()
 # TRYTOND_CONFIG it's managed by importing config
 db_names = os.environ.get('TRYTOND_DATABASE_NAMES')
+db_list = []
 if db_names:
     # Read with csv so database name can include special chars
     reader = csv.reader(StringIO(db_names))
     threads = []
     for name in next(reader):
+        db_list.append(name)
         thread = threading.Thread(target=lambda: Pool(name).init())
         thread.start()
         threads.append(thread)
@@ -65,3 +69,21 @@
 
 Pool.app_initialization_completed()
 assert len(threads := threading.enumerate()) == 1, f"len({threads}) != 1"
+
+
+@uwsgidecorators.postfork
+def preload():
+    from trytond.transaction import Transaction
+    from trytond.cache import Cache
+    pid = os.getpid()
+    for db_name in db_list:
+        if (pid, db_name) not in Cache._listener:
+            if not Cache._clean_last:
+                Cache._clean_last = datetime.date.min
+            with Transaction().start(db_name, 0, readonly=True):
+                # Starting a transaction will trigger `Cache.sync`, which
+                # should spawn a thread to listen for cache invalidation and
+                # pool refresh events
+                pass
+        if (pid, db_name) not in Cache._listener:
+            raise AssertionError
diff --git a/trytond/trytond/cache.py b/trytond/trytond/cache.py
index 744dea10033..a2cd69e8a65 100644
--- a/trytond/trytond/cache.py
+++ b/trytond/trytond/cache.py
@@ -8,6 +8,7 @@
 import threading
 from collections import OrderedDict, defaultdict
 from copy import deepcopy
+from uuid import uuid4
 from weakref import WeakKeyDictionary
 
 from sql import Table
@@ -160,6 +161,8 @@ class MemoryCache(BaseCache):
     _default_lower = Transaction.monotonic_time()
     _listener = {}
     _listener_lock = defaultdict(threading.Lock)
+    _listener_id = None
+    _listener_id_lock = threading.Lock()
     _table = 'ir_cache'
     _channel = _table
 
@@ -375,10 +378,15 @@ def refresh_pool(cls, transaction):
         if not _clear_timeout and database.has_channel():
             database = backend.Database(dbname)
             conn = database.get_connection()
+            with cls._listener_id_lock:
+                if cls._listener_id:
+                    process_id = cls._listener_id
+                else:
+                    cls._listener_id = process_id = uuid4()
+            payload = json.dumps(('refresh_pool', str(process_id)))
             try:
                 cursor = conn.cursor()
-                cursor.execute(
-                    'NOTIFY "%s", %%s' % cls._channel, ('refresh pool',))
+                cursor.execute(f'NOTIFY "{cls._channel}", %s', (payload,))
                 conn.commit()
             finally:
                 database.put_connection(conn)
@@ -417,13 +425,19 @@ def _listen(cls, dbname):
                     pool = Pool(dbname)
                     callbacks = pool._notification_callbacks.get(dbname, {})
                     notification = conn.notifies.pop()
-                    if notification.payload == 'refresh pool':
-                        Pool.refresh(dbname, _get_modules(cursor))
-                    elif notification.payload in callbacks:
-                        callbacks[notification.payload](pool)
-                    elif notification.payload:
-                        reset = json.loads(notification.payload)
-                        for name in reset:
+                    payload = json.loads(notification.payload)
+                    if payload and payload[0] == 'refresh_pool':
+                        with cls._listener_id_lock:
+                            if cls._listener_id:
+                                process_id = cls._listener_id
+                            else:
+                                cls._listener_id = process_id = uuid4()
+                        if payload[1] != str(process_id):
+                            Pool.refresh(dbname, _get_modules(cursor))
+                    elif isinstance(payload, str) and payload in callbacks:
+                        callbacks[payload](pool)
+                    elif payload:
+                        for name in payload:
                             # XUNG
                             # Name not in instances when control_vesion_upgrade
                             # table is locked because another process is
diff --git a/trytond/trytond/ir/module.py b/trytond/trytond/ir/module.py
index 6f4a1b15399..d04add57ead 100644
--- a/trytond/trytond/ir/module.py
+++ b/trytond/trytond/ir/module.py
@@ -5,7 +5,6 @@
 
 from sql.operators import NotIn
 
-from trytond.cache import Cache
 from trytond.exceptions import UserError
 from trytond.i18n import gettext
 from trytond.model import ModelSQL, ModelView, Unique, fields, sequence_ordered
@@ -503,7 +502,6 @@ def transition_upgrade(self):
             lang = [x.code for x in langs]
         if update:
             pool.init(update=update, lang=lang)
-            Cache.refresh_pool(transaction)
         return 'done'
 
     def transition_next_(self):
diff --git a/trytond/trytond/pool.py b/trytond/trytond/pool.py
index abc9542569b..dbb55e0cea0 100644
--- a/trytond/trytond/pool.py
+++ b/trytond/trytond/pool.py
@@ -165,7 +165,6 @@ def stop(cls, database_name):
         '''
         with cls._lock:
             cls._pools.pop(database_name, None)
-            cls._pool_instances.clear()
 
     @classmethod
     def database_list(cls):
@@ -203,6 +202,7 @@ def init(self, update=None, lang=None, activatedeps=False, indexes=None):
             self._pools[self.database_name] = self._pool
             self._pool_modules[self.database_name] = self._modules
             self._pool_instances.clear()
+            self._pool_instances.add(self)
             if restart:
                 self.init()