Due to the high channel count and the need to consider information from many adjacent channels in the sorting of each spike, many existing spike sorting algorithms are insufficient or unusable for data produced by Neuropixels probes.
Automatic spike sorting
Kilosort is an automatic spike sorting algorithm developed for Neuropixels probes that can process the data quickly and accurately. Find the code for Kilosort here and a paper about how it works here. Kilosort outperformed other tested algorithms in an objective comparison.
A channel map file for using Neuropixels data with Kilosort (if the data were recorded with SpikeGLX, at least) can be found here in this repository.
Manual revision of automatic results
Phy is a gui for manually reviewing and modifying the results of the automatic algorithm. The template-gui has been developed for use with results produced by Kilosort.
See this documentation for a user-friendly guide to spike sorting Neuropixels data.