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rolypoly

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This package is meant to identify enrichment of SNP-trait association signal in functional annotations.

Install

install.packages("rolypoly")

Usage

For usage information see the introductory vignette. Additionally, refer to the manual for documentation of rolypoly functions.

Notes

  • Still in early alpha phase.

Citation

The underlying model is described in: Calderon D (2017). Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. AJHG 10.1016/j.ajhg.2017.09.009

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Method for identifying trait-relevant gene annotations from GWAS summary statistics.

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