diff --git a/.travis.yml b/.travis.yml
index a09e43e1..ec14a47d 100644
--- a/.travis.yml
+++ b/.travis.yml
@@ -113,7 +113,7 @@ before_script:
      -DCMAKE_Fortran_COMPILER=${Fortran_COMPILER}
      -DCMAKE_BUILD_TYPE=${BUILD_TYPE}
      -DENABLE_CODE_COVERAGE=${COVERAGE}
-     -DENABLE_PYTHON_INTERFACE=ON
+     -DXCFun_ENABLE_PYTHON_INTERFACE=ON
      -DPYTHON_EXECUTABLE=$(which python)
      -DCMAKE_INSTALL_PREFIX=$HOME/Software/xcfun
      ${PYBIND11}
diff --git a/cmake/custom/xcfun.cmake b/cmake/custom/xcfun.cmake
index 5a2e82a8..4a4d54cc 100644
--- a/cmake/custom/xcfun.cmake
+++ b/cmake/custom/xcfun.cmake
@@ -5,7 +5,7 @@
 # Variables modified::
 #
 #   XCFun_XC_MAX_ORDER -- Maximum order of derivatives of the exchange-correlation kernel
-#   ENABLE_PYTHON_INTERFACE -- Whether to enable the Python interface
+#   XCFun_ENABLE_PYTHON_INTERFACE -- Whether to enable the Python interface
 #
 # autocmake.yml configuration::
 #
@@ -14,7 +14,7 @@
 #     - "--pybindings Enable Python interface [default: OFF]."
 #   define:
 #     - "'-DXCFun_XC_MAX_ORDER=\"{0}\"'.format(arguments['--xcmaxorder'])"
-#     - "'-DENABLE_PYTHON_INTERFACE={0}'.format(arguments['--pybindings'])"
+#     - "'-DXCFun_ENABLE_PYTHON_INTERFACE={0}'.format(arguments['--pybindings'])"
 
 option_with_default(XCFun_XC_MAX_ORDER "Maximum order of derivatives of the exchange-correlation kernel" 3)
 # Make sure user selected a valuer larger than 2
@@ -41,7 +41,7 @@ else()
 endif()
 file(TO_NATIVE_PATH "lib/${PYMOD_INSTALL_LIBDIR}/xcfun" PYMOD_INSTALL_FULLDIR)
 
-option_with_print(ENABLE_PYTHON_INTERFACE "Enable Python interface" OFF)
+option_with_print(XCFun_ENABLE_PYTHON_INTERFACE "Enable Python interface" OFF)
 
 if(ENABLE_FC_SUPPORT)
   enable_language(Fortran)
@@ -55,7 +55,7 @@ endif()
 add_subdirectory(${PROJECT_SOURCE_DIR}/api)
 add_subdirectory(${PROJECT_SOURCE_DIR}/src)
 
-if(ENABLE_PYTHON_INTERFACE)
+if(XCFun_ENABLE_PYTHON_INTERFACE)
   include(${PROJECT_SOURCE_DIR}/external/upstream/fetch_pybind11.cmake)
   add_subdirectory(python)
 endif()
diff --git a/setup b/setup
index edf19fff..901b79b3 100755
--- a/setup
+++ b/setup
@@ -53,7 +53,7 @@ def gen_cmake_command(options, arguments):
     command.append('-DENABLE_CODE_COVERAGE={0}'.format(arguments['--coverage']))
     command.append('-DSTATIC_LIBRARY_ONLY={0}'.format(arguments['--static']))
     command.append('-DXCFun_XC_MAX_ORDER="{0}"'.format(arguments['--xcmaxorder']))
-    command.append('-DENABLE_PYTHON_INTERFACE={0}'.format(arguments['--pybindings']))
+    command.append('-DXCFun_ENABLE_PYTHON_INTERFACE={0}'.format(arguments['--pybindings']))
     command.append('-DCMAKE_BUILD_TYPE={0}'.format(arguments['--type']))
     command.append('-G"{0}"'.format(arguments['--generator']))
     if arguments['--cmake-options'] != "''":
diff --git a/test/CMakeLists.txt b/test/CMakeLists.txt
index 5447d7ae..c89b701c 100644
--- a/test/CMakeLists.txt
+++ b/test/CMakeLists.txt
@@ -32,7 +32,7 @@ if(ENABLE_FC_SUPPORT)
   add_test(fortran_example ${CMAKE_RUNTIME_OUTPUT_DIRECTORY}/fortran_example)
 endif()
 
-if(ENABLE_PYTHON_INTERFACE)
+if(XCFun_ENABLE_PYTHON_INTERFACE)
   list(APPEND _pytest_files
     ${CMAKE_CURRENT_SOURCE_DIR}/test_xcfun.py
     )