I ran into a reproducible issue with Dhewm3, which freezes the game completely. It happens just after I cancelled the distress signal. When loading the quicksave, All I do is a step forward and looking to the left, and the game freezes.
Save game:
QuickSave.zip
Log:
Dhewm3FreezeLog.txt
The log is sadly useless I fear, since the issue freezes the machine, forcing me to use gdb to terminate the program. When running without gdb, the issue also happens and I have to kill the task instead. As always, if you need more info, feel free to ask.