diff --git a/packages/react-native/ReactCommon/react/runtime/hermes/HermesInstance.cpp b/packages/react-native/ReactCommon/react/runtime/hermes/HermesInstance.cpp
index f0678d80717b..11de62a0de66 100644
--- a/packages/react-native/ReactCommon/react/runtime/hermes/HermesInstance.cpp
+++ b/packages/react-native/ReactCommon/react/runtime/hermes/HermesInstance.cpp
@@ -112,7 +112,7 @@ class HermesJSRuntime : public JSRuntime {
   void unstable_initializeOnJsThread() override {
     // On new arch, we're seeing a crash in release optimized builds here. Adding this as a stopgap measure to prevent
     // the crash to allow us to more thoroughly test new arch while this is investigated.
-#ifdef HERMES_ENABLE_PROFILING
+#ifndef DISABLE_HERMES_PROFILING_WORKAROUND
     runtime_->registerForProfiling();
 #endif
   }