Gaia is the interface for Mozilla's new Phone Operating System: http://hacks.mozilla.org/2012/02/gaia-mozillas-user-interface-for-boot-to-gecko-all-web-technologies/ and https://github.com/andreasgal/gaia
As applications are just HTML5, we could do up a DocPad skeleton for developing them.
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Updated Gaia link: https://github.com/mozilla-b2g/gaia
There is also WinJS for Windows apps that span the OS, the phone and the Xbox: