diff --git a/DependencyInjection/DoctrineExtension.php b/DependencyInjection/DoctrineExtension.php
index 044235f3..97857911 100644
--- a/DependencyInjection/DoctrineExtension.php
+++ b/DependencyInjection/DoctrineExtension.php
@@ -109,6 +109,10 @@ public function load(array $configs, ContainerBuilder $container)
             $this->loadMessengerServices($container);
         }
 
+        if (! $container->hasParameter('kernel.runtime_mode') || ! $container->hasParameter('kernel.runtime_mode.worker')) {
+            $container->removeDefinition('doctrine.connection.keep.alive_middleware');
+        }
+
         if (empty($config['orm'])) {
             return;
         }
diff --git a/Resources/config/middlewares.xml b/Resources/config/middlewares.xml
index d6bf92bc..610f8c2f 100644
--- a/Resources/config/middlewares.xml
+++ b/Resources/config/middlewares.xml
@@ -17,5 +17,10 @@
             <argument type="service" id="doctrine.debug_data_holder" />
             <argument type="service" id="debug.stopwatch" on-invalid="null" />
         </service>
+        <service id="doctrine.connection.keep.alive_middleware" class="Symfony\Bridge\Doctrine\Middleware\ConnectionKeepAlive">
+            <argument type="service" id="doctrine" />
+            <argument type="service" id="service_container"  />
+            <tag name="doctrine.middleware" />
+        </service>
     </services>
 </container>
diff --git a/Tests/ConnectionKeepAliveMiddlewareTest.php b/Tests/ConnectionKeepAliveMiddlewareTest.php
new file mode 100644
index 00000000..63355f5e
--- /dev/null
+++ b/Tests/ConnectionKeepAliveMiddlewareTest.php
@@ -0,0 +1,182 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Bundle\DoctrineBundle\Tests;
+
+use Doctrine\DBAL\Connection;
+use Doctrine\DBAL\Driver;
+use Doctrine\DBAL\Driver\Connection as DriverConnection;
+use Doctrine\DBAL\Driver\Middleware\AbstractDriverMiddleware;
+use Doctrine\DBAL\Exception as DBALException;
+use Doctrine\DBAL\Platforms\AbstractPlatform;
+use Doctrine\DBAL\Result;
+use Doctrine\ORM\EntityManagerInterface;
+use Doctrine\Persistence\ManagerRegistry;
+use PHPUnit\Framework\MockObject\MockObject;
+use PHPUnit\Framework\TestCase;
+use Symfony\Bridge\Doctrine\CheckConnection;
+use Symfony\Component\DependencyInjection\Container;
+use Symfony\Component\DependencyInjection\ContainerInterface;
+
+/**
+ * Based on https://github.com/Baldinof/roadrunner-bundle/blob/3.x/src/Integration/Doctrine/DoctrineORMMiddleware.php
+ */
+class ConnectionKeepAliveMiddlewareTest extends TestCase
+{
+    public const CONNECTION_NAME = 'doctrine.connection';
+    public const MANAGER_NAME    = 'doctrine.manager';
+
+    private MockObject&ManagerRegistry $managerRegistryMock;
+    private MockObject&Connection $connectionMock;
+    private ContainerInterface $container;
+    private MockObject&Driver $driver;
+    private DoctrineConnectionDriverTest $doctrineConnectionDriver;
+
+    public function setUp(): void
+    {
+        $platform = $this->createMock(AbstractPlatform::class);
+        $platform->method('getDummySelectSQL')->willReturn('SELECT 1');
+
+        $this->managerRegistryMock = $this->createMock(ManagerRegistry::class);
+        $this->connectionMock = $this->createMock(Connection::class);
+        $this->connectionMock->method('getDatabasePlatform')->willReturn($platform);
+        $connectionDriverMock = $this->createMock(Driver\Connection::class);
+
+        $this->container = new Container();
+        $this->container->set(self::CONNECTION_NAME, $this->connectionMock);
+
+        $this->managerRegistryMock->method('getConnectionNames')->willReturn([self::CONNECTION_NAME]);
+        $this->managerRegistryMock->method('getManagerNames')->willReturn([self::MANAGER_NAME]);
+
+        $this->driver = $this->createMock(Driver::class);
+        $this->driver->method('connect')->willReturn($connectionDriverMock);
+
+        $this->doctrineConnectionDriver = new DoctrineConnectionDriverTest($this->driver, $this->managerRegistryMock, $this->container);
+    }
+
+    public function testSkipNotInitializedConnections()
+    {
+        $this->container->set(self::CONNECTION_NAME, null);
+
+        $this->connectionMock->expects($this->never())->method('isConnected');
+        $this->connectionMock->expects($this->never())->method('executeQuery');
+        $this->connectionMock->expects($this->never())->method('close');
+        $this->connectionMock->expects($this->never())->method('connect');
+
+        $this->doctrineConnectionDriver->connect([]);
+    }
+
+    public function testSkipWhenNotConnected(): void
+    {
+        $this->connectionMock->method('isConnected')->willReturn(false);
+        $this->connectionMock->expects($this->never())->method('executeQuery');
+        $this->connectionMock->expects($this->never())->method('close');
+        $this->connectionMock->expects($this->never())->method('connect');
+
+        $this->doctrineConnectionDriver->connect([]);
+    }
+
+    public function testItClosesNotPingableConnection(): void
+    {
+        $this->connectionMock->expects($this->exactly(2))->method('executeQuery')
+            ->willReturnCallback(function () {
+                static $counter = 0;
+
+                if (1 === ++$counter) {
+                    throw $this->createMock(DBALException::class);
+                }
+
+                return $this->createMock(Result::class);
+            });
+
+        $this->connectionMock->method('isConnected')->willReturn(true);
+        $this->connectionMock->expects($this->once())->method('close');
+        $this->connectionMock->expects($this->never())->method('connect');
+
+        $this->doctrineConnectionDriver->connect([]);
+    }
+
+    public function testItDoesNotClosePingableConnection(): void
+    {
+        $this->connectionMock->expects($this->once())->method('executeQuery');
+        $this->connectionMock->method('isConnected')->willReturn(true);
+        $this->connectionMock->expects($this->never())->method('close');
+        $this->connectionMock->expects($this->never())->method('connect');
+
+        $this->doctrineConnectionDriver->connect([]);
+    }
+
+    public function testItForcesRebootOnClosedManagerWhenMissingProxySupport()
+    {
+        $manager = $this->createMock(EntityManagerInterface::class);
+        $this->container->set(self::MANAGER_NAME, $manager);
+
+        $manager->expects($this->once())->method('isOpen')->willReturn(false);
+        $this->managerRegistryMock->expects($this->once())
+            ->method('resetManager')
+            ->with(self::MANAGER_NAME);
+
+        $this->doctrineConnectionDriver->connect([]);
+    }
+}
+
+class DoctrineConnectionDriverTest extends AbstractDriverMiddleware
+{
+    private Driver $driver;
+    private ManagerRegistry $managerRegistry;
+    private ContainerInterface $container;
+
+    public function __construct(Driver $driver, ManagerRegistry $managerRegistry, ContainerInterface $container)
+    {
+        $this->driver          = $driver;
+        $this->managerRegistry = $managerRegistry;
+        $this->container       = $container;
+
+        parent::__construct($driver);
+    }
+
+    /**
+     * {@inheritDoc}
+     */
+    public function connect(array $params): DriverConnection
+    {
+        $connectionServices = $this->managerRegistry->getConnectionNames();
+
+        foreach ($connectionServices as $connectionServiceName) {
+            if (! $this->container->initialized($connectionServiceName)) {
+                continue;
+            }
+
+            $connection = $this->container->get($connectionServiceName);
+
+            if (! $connection instanceof Connection) {
+                continue;
+            }
+
+            if ($connection->isConnected()) {
+                CheckConnection::reconnectOnFailure($connection);
+            }
+
+            $managerNames = $this->managerRegistry->getManagerNames();
+
+            foreach ($managerNames as $managerName) {
+                if (! $this->container->initialized($managerName)) {
+                    continue;
+                }
+
+                $manager = $this->container->get($managerName);
+
+                if (! $manager instanceof EntityManagerInterface) {
+                    continue;
+                }
+
+                if (! $manager->isOpen()) {
+                    $this->managerRegistry->resetManager($managerName);
+                }
+            }
+        }
+
+        return parent::connect($params);
+    }
+}