diff --git a/wx/lib/activexwrapper.py b/wx/lib/activexwrapper.py
index 026301a..74f460c 100644
--- a/wx/lib/activexwrapper.py
+++ b/wx/lib/activexwrapper.py
@@ -66,7 +66,7 @@ def MakeActiveXClass(CoClass, eventClass=None, eventObj=None):
     """
 
 
-    if type(CoClass) == type(""):
+    if type(CoClass) == str:
         # use the CLSID to get the real class
         CoClass = win32com.client.CLSIDToClass(CoClass)
 
diff --git a/wx/lib/agw/artmanager.py b/wx/lib/agw/artmanager.py
index bf35527..1fdd827 100644
--- a/wx/lib/agw/artmanager.py
+++ b/wx/lib/agw/artmanager.py
@@ -6,7 +6,7 @@
 import wx
 import random
 
-from six import BytesIO
+from io import BytesIO
 
 from .fmresources import *
 
@@ -206,7 +206,7 @@ def DrawButton(self, dc, rect, state, input=None):
         :param `input`: a flag used to call the right method.
         """
 
-        if input is None or type(input) == type(False):
+        if input is None or type(input) == bool:
             self.DrawButtonTheme(dc, rect, state, input)
         else:
             self.DrawButtonColour(dc, rect, state, input)
@@ -1236,7 +1236,7 @@ def DrawButton(self, dc, rect, theme, state, input=None):
         :param `input`: a flag used to call the right method.
         """
 
-        if input is None or type(input) == type(False):
+        if input is None or type(input) == bool:
             self.DrawButtonTheme(dc, rect, theme, state, input)
         else:
             self.DrawButtonColour(dc, rect, theme, state, input)
diff --git a/wx/lib/agw/cubecolourdialog.py b/wx/lib/agw/cubecolourdialog.py
index d221036..aa023e6 100644
--- a/wx/lib/agw/cubecolourdialog.py
+++ b/wx/lib/agw/cubecolourdialog.py
@@ -2308,7 +2308,7 @@ def OnPaint(self, event):
         vstep = 1.0/(brightRect.height-1)
 
         for y_pos in range(brightRect.y, brightRect.height+brightRect.y):
-            r, g, b = [c * 255.0 for c in colorsys.hsv_to_rgb(h, s, v)]
+            r, g, b = (c * 255.0 for c in colorsys.hsv_to_rgb(h, s, v))
             colour = wx.Colour(int(r), int(g), int(b))
             dc.SetPen(wx.Pen(colour, 1, wx.PENSTYLE_SOLID))
             dc.DrawRectangle(brightRect.x, y_pos, brightRect.width, 1)
diff --git a/wx/lib/agw/customtreectrl.py b/wx/lib/agw/customtreectrl.py
index feaa00a..edc812d 100644
--- a/wx/lib/agw/customtreectrl.py
+++ b/wx/lib/agw/customtreectrl.py
@@ -5184,7 +5184,7 @@ def InsertItem(self, parentId, input, text, ct_type=0, wnd=None, image=-1, selIm
         :see: :meth:`~CustomTreeCtrl.DoInsertItem` for possible exceptions generated by this method.
         """
 
-        if type(input) == type(1):
+        if type(input) == int:
             return self.InsertItemByIndex(parentId, input, text, ct_type, wnd, image, selImage, data, separator, on_the_right)
         else:
             return self.InsertItemByItem(parentId, input, text, ct_type, wnd, image, selImage, data, separator, on_the_right)
diff --git a/wx/lib/agw/flatmenu.py b/wx/lib/agw/flatmenu.py
index 2f47d8a..6c9b13a 100644
--- a/wx/lib/agw/flatmenu.py
+++ b/wx/lib/agw/flatmenu.py
@@ -4097,7 +4097,7 @@ def Move(self, input1, input2=None):
         :param `input2`: if not ``None``, it is an integer representing the button `y` position.
         """
 
-        if type(input) == type(1):
+        if type(input) == int:
             self._pos = wx.Point(input1, input2)
         else:
             self._pos = input1
@@ -4113,7 +4113,7 @@ def SetSize(self, input1, input2=None):
         :param `input2`: if not ``None``, it is an integer representing the button height.
         """
 
-        if type(input) == type(1):
+        if type(input) == int:
             self._size = wx.Size(input1, input2)
         else:
             self._size = input1
@@ -6647,7 +6647,7 @@ def Remove(self, item):
         :param `item`: can be either a menu item identifier or a plain :class:`FlatMenuItem`.
         """
 
-        if type(item) != type(1):
+        if type(item) != int:
             item = item.GetId()
 
         return self._RemoveById(item)
@@ -6674,7 +6674,7 @@ def DestroyItem(self, item):
         :param `item`: can be either a menu item identifier or a plain :class:`FlatMenuItem`.
         """
 
-        if type(item) != type(1):
+        if type(item) != int:
             item = item.GetId()
 
         self._DestroyById(item)
diff --git a/wx/lib/agw/flatnotebook.py b/wx/lib/agw/flatnotebook.py
index e594d2d..c088f33 100644
--- a/wx/lib/agw/flatnotebook.py
+++ b/wx/lib/agw/flatnotebook.py
@@ -887,12 +887,12 @@ def AdjustColour(colour, percent, alpha=wx.ALPHA_OPAQUE):
 
     """
 
-    radj, gadj, badj = [int(val * (abs(percent) / 100.)) for val in colour.Get()]
+    radj, gadj, badj = (int(val * (abs(percent) / 100.)) for val in colour.Get())
 
     if percent < 0:
-        radj, gadj, badj = [val * -1 for val in [radj, gadj, badj]]
+        radj, gadj, badj = (val * -1 for val in [radj, gadj, badj])
     else:
-        radj, gadj, badj = [val or 255 for val in [radj, gadj, badj]]
+        radj, gadj, badj = (val or 255 for val in [radj, gadj, badj])
 
     red = min(colour.Red() + radj, 255)
     green = min(colour.Green() + gadj, 255)
diff --git a/wx/lib/agw/floatspin.py b/wx/lib/agw/floatspin.py
index 87cf810..c5172ee 100644
--- a/wx/lib/agw/floatspin.py
+++ b/wx/lib/agw/floatspin.py
@@ -1325,7 +1325,7 @@ def __init__(self, value=0, precision=DEFAULT_PRECISION):
         self.set_precision(precision)
         p = self.p
 
-        if isinstance(value, type("42.3e5")):
+        if isinstance(value, str):
             n, exp = _string2exact(value)
             # exact value is n*10**exp = n*10**(exp+p)/10**p
             effective_exp = exp + p
@@ -1346,7 +1346,7 @@ def __init__(self, value=0, precision=DEFAULT_PRECISION):
             self.n, self.p = temp.n, temp.p
             return
 
-        if isinstance(value, type(42.0)):
+        if isinstance(value, float):
             # XXX ignoring infinities and NaNs and overflows for now
             import math
             f, e = math.frexp(abs(value))
diff --git a/wx/lib/analogclock/setup.py b/wx/lib/analogclock/setup.py
index 1454713..114ef70 100644
--- a/wx/lib/analogclock/setup.py
+++ b/wx/lib/analogclock/setup.py
@@ -332,10 +332,10 @@ def __init__(self, parent):
 
     def OnChanged(self, evt):
         clockStyle, hourStyle, minuteStyle = \
-          [functools.reduce(lambda x, y: x | y,
+          (functools.reduce(lambda x, y: x | y,
            [getattr(styles, item) \
             for item in self.GetStringItemsChecked(group)], 0) \
-            for group in self.groups]
+            for group in self.groups)
 
         self.clock.SetClockStyle(clockStyle)
         self.clock.SetTickStyle(hourStyle, styles.HOUR)
diff --git a/wx/lib/colourchooser/pycolourslider.py b/wx/lib/colourchooser/pycolourslider.py
index 633c886..92fcc4b 100644
--- a/wx/lib/colourchooser/pycolourslider.py
+++ b/wx/lib/colourchooser/pycolourslider.py
@@ -92,7 +92,7 @@ def DrawBuffer(self):
         v = 1.0
         vstep = 1.0 / self.HEIGHT
         for y_pos in range(0, self.HEIGHT):
-            r,g,b = [c * 255.0 for c in colorsys.hsv_to_rgb(h,s,v)]
+            r,g,b = (c * 255.0 for c in colorsys.hsv_to_rgb(h,s,v))
             colour = wx.Colour(int(r), int(g), int(b))
             self.buffer.SetPen(wx.Pen(colour, 1, wx.PENSTYLE_SOLID))
             self.buffer.DrawRectangle(0, y_pos, 15, 1)
diff --git a/wx/lib/colourutils.py b/wx/lib/colourutils.py
index 3a145bf..508c614 100644
--- a/wx/lib/colourutils.py
+++ b/wx/lib/colourutils.py
@@ -57,13 +57,13 @@ def AdjustColour(color, percent, alpha=wx.ALPHA_OPAQUE):
      specified as input
     """
 
-    radj, gadj, badj = [ int(val * (abs(percent) / 100.))
-                         for val in color.Get(includeAlpha=False) ]
+    radj, gadj, badj = ( int(val * (abs(percent) / 100.))
+                         for val in color.Get(includeAlpha=False) )
 
     if percent < 0:
-        radj, gadj, badj = [ val * -1 for val in [radj, gadj, badj] ]
+        radj, gadj, badj = ( val * -1 for val in [radj, gadj, badj] )
     else:
-        radj, gadj, badj = [ val or 255 for val in [radj, gadj, badj] ]
+        radj, gadj, badj = ( val or 255 for val in [radj, gadj, badj] )
 
     red = min(color.Red() + radj, 255)
     green = min(color.Green() + gadj, 255)
diff --git a/wx/lib/embeddedimage.py b/wx/lib/embeddedimage.py
index 159a682..0ca58b1 100644
--- a/wx/lib/embeddedimage.py
+++ b/wx/lib/embeddedimage.py
@@ -15,7 +15,7 @@
 import base64
 
 import wx
-from six import BytesIO
+from io import BytesIO
 
 try:
     b64decode = base64.b64decode
diff --git a/wx/lib/floatcanvas/Resources.py b/wx/lib/floatcanvas/Resources.py
index 84067b0..067cca1 100644
--- a/wx/lib/floatcanvas/Resources.py
+++ b/wx/lib/floatcanvas/Resources.py
@@ -4,7 +4,7 @@
 from wx import Image as ImageFromStream
 from wx import Bitmap as BitmapFromImage
 
-from six import BytesIO
+from io import BytesIO
 import zlib
 
 
diff --git a/wx/lib/floatcanvas/ScreenShot.py b/wx/lib/floatcanvas/ScreenShot.py
index b308dfa..04a3b37 100644
--- a/wx/lib/floatcanvas/ScreenShot.py
+++ b/wx/lib/floatcanvas/ScreenShot.py
@@ -4,7 +4,7 @@
 from wx import Image as ImageFromStream
 from wx import BitmapFromImage
 
-from six import BytesIO
+from io import BytesIO
 import zlib
 
 
diff --git a/wx/lib/masked/maskededit.py b/wx/lib/masked/maskededit.py
index 1ecfc5e..43cc0c3 100644
--- a/wx/lib/masked/maskededit.py
+++ b/wx/lib/masked/maskededit.py
@@ -4425,7 +4425,7 @@ def _adjustFloat(self, candidate=None):
         'Fixes' an floating point control. Collapses spaces, right-justifies, etc.
         """
 ##        dbg('MaskedEditMixin::_adjustFloat, candidate = "%s"' % candidate, indent=1)
-        lenInt,lenFraction  = [len(s) for s in self._mask.split('.')]  ## Get integer, fraction lengths
+        lenInt,lenFraction  = (len(s) for s in self._mask.split('.'))  ## Get integer, fraction lengths
 
         if candidate is None: value = self._GetValue()
         else: value = candidate
diff --git a/wx/lib/pdfviewer/viewer.py b/wx/lib/pdfviewer/viewer.py
index d797bfa..71975cf 100644
--- a/wx/lib/pdfviewer/viewer.py
+++ b/wx/lib/pdfviewer/viewer.py
@@ -30,7 +30,8 @@
 import types
 import copy
 import shutil
-from six import BytesIO, string_types
+from six import string_types
+from io import BytesIO
 
 import wx
 
@@ -659,7 +660,7 @@ def ProcessOperators(self, opslist, pdf_fonts):
             if operator == 'cm' and operand:        # new transformation matrix
                 # some operands need inverting because directions of y axis
                 # in pdf and graphics context are opposite
-                a, b, c, d, e, f = [float(n) for n in operand]
+                a, b, c, d, e, f = (float(n) for n in operand)
                 drawlist.append(['ConcatTransform', (a, -b, -c, d, e, -f), {}])
             elif operator == 'q':       # save state
                 self.saved_state.append(copy.deepcopy(g))
@@ -668,10 +669,10 @@ def ProcessOperators(self, opslist, pdf_fonts):
                 self.gstate = self.saved_state.pop()
                 drawlist.append(['PopState', (), {}])
             elif operator == 'RG':      # Stroke RGB
-                rs, gs, bs = [int(float(n)*255) for n in operand]
+                rs, gs, bs = (int(float(n)*255) for n in operand)
                 g.strokeRGB = wx.Colour(rs, gs, bs)
             elif operator == 'rg':      # Fill RGB
-                rf, gf, bf = [int(float(n)*255) for n in operand]
+                rf, gf, bf = (int(float(n)*255) for n in operand)
                 g.fillRGB = wx.Colour(rf, gf, bf)
             elif operator == 'K':       # Stroke CMYK
                 rs, gs, bs = self.ConvertCMYK(operand)
diff --git a/wx/py/images.py b/wx/py/images.py
index fd46033..71bee77 100644
--- a/wx/py/images.py
+++ b/wx/py/images.py
@@ -3,7 +3,7 @@
 __author__ = "Patrick K. O'Brien <pobrien@orbtech.com> / David Mashburn <david.n.mashburn@gmail.com>"
 
 import wx
-from six import BytesIO
+from io import BytesIO
 
 def getPyIcon(shellName='PyCrust'):
     icon = wx.Icon()
diff --git a/wx/py/interpreter.py b/wx/py/interpreter.py
index eff11c8..f0d866f 100644
--- a/wx/py/interpreter.py
+++ b/wx/py/interpreter.py
@@ -25,7 +25,7 @@ def __init__(self, locals=None, rawin=None,
         self.stdout = stdout
         self.stderr = stderr
         if rawin:
-            from six.moves import builtins
+            import builtins
             builtins.raw_input = rawin
             del builtins
         if showInterpIntro:
diff --git a/wx/py/introspect.py b/wx/py/introspect.py
index dcff192..ec37b40 100644
--- a/wx/py/introspect.py
+++ b/wx/py/introspect.py
@@ -8,7 +8,8 @@
 import tokenize
 import types
 import wx
-from six import BytesIO, PY3, string_types
+from six import PY3, string_types
+from io import BytesIO
 
 def getAutoCompleteList(command='', locals=None, includeMagic=1,
                         includeSingle=1, includeDouble=1):
diff --git a/wx/py/shell.py b/wx/py/shell.py
index 6dec308..fe593ec 100644
--- a/wx/py/shell.py
+++ b/wx/py/shell.py
@@ -403,7 +403,7 @@ def setBuiltinKeywords(self):
 
         This sets "close", "exit" and "quit" to a helpful string.
         """
-        from six.moves import builtins
+        import builtins
         builtins.close = builtins.exit = builtins.quit = \
             'Click on the close button to leave the application.'
         builtins.cd = cd
diff --git a/wx/tools/pywxrc.py b/wx/tools/pywxrc.py
index 103dc7c..6d3556e 100644
--- a/wx/tools/pywxrc.py
+++ b/wx/tools/pywxrc.py
@@ -854,7 +854,7 @@ def _OpenOutputFile(self, outputFilename):
                             block = None
 
             try:
-                outputFile = open(outputFilename, "wt")
+                outputFile = open(outputFilename, "w")
             except OSError:
                 raise OSError("Can't write output to '%s'" % outputFilename)
         return outputFile