diff --git a/eng/pipelines/libraries/helix-queues-setup.yml b/eng/pipelines/libraries/helix-queues-setup.yml
index 75d6cbd212217..f5bb09d41b441 100644
--- a/eng/pipelines/libraries/helix-queues-setup.yml
+++ b/eng/pipelines/libraries/helix-queues-setup.yml
@@ -189,6 +189,6 @@ jobs:
 
     # WebAssembly windows
     - ${{ if eq(parameters.platform, 'Browser_wasm_win') }}:
-      - (Windows.Server.Core.1909.Amd64.Open)windows.10.amd64.server20h1.open@mcr.microsoft.com/dotnet-buildtools/prereqs:windowsservercore-2004-helix-webassembly-amd64-20210531091615-f5c7a43
+      - (Windows.Server.Core.1909.Amd64.Open)windows.10.amd64.server20h1.open@mcr.microsoft.com/dotnet-buildtools/prereqs:windowsservercore-2004-helix-webassembly-amd64-20210702131541-6837048
 
     ${{ insert }}: ${{ parameters.jobParameters }}
diff --git a/eng/pipelines/runtime-staging.yml b/eng/pipelines/runtime-staging.yml
index f58caca2899de..72ddbd6be47d0 100644
--- a/eng/pipelines/runtime-staging.yml
+++ b/eng/pipelines/runtime-staging.yml
@@ -354,7 +354,7 @@ jobs:
       timeoutInMinutes: 90
 
 #
-# Build Browser_wasm, on windows
+# Build Browser_wasm, on windows, run console and browser tests
 #
 - template: /eng/pipelines/common/platform-matrix.yml
   parameters:
@@ -374,7 +374,7 @@ jobs:
       testGroup: innerloop
       nameSuffix: Browser_wasm_Windows
       buildArgs: -subset mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true /p:BrowserHost=windows
-      timeoutInMinutes: 120
+      timeoutInMinutes: 180
       condition: >-
         or(
           eq(dependencies.evaluate_paths.outputs['SetPathVars_libraries.containsChange'], true),
@@ -389,6 +389,7 @@ jobs:
         extraHelixArguments: /p:BrowserHost=windows
         scenarios:
         - normal
+        - wasmtestonbrowser
         condition: >-
           or(
           eq(variables['librariesContainsChange'], true),
diff --git a/eng/testing/tests.wasm.targets b/eng/testing/tests.wasm.targets
index 16edf35847b83..8618fdb73e3c5 100644
--- a/eng/testing/tests.wasm.targets
+++ b/eng/testing/tests.wasm.targets
@@ -22,6 +22,7 @@
     <_XHarnessArgs Condition="'$(OS)' == 'Windows_NT'">wasm %XHARNESS_COMMAND% --app=. --output-directory=%XHARNESS_OUT%</_XHarnessArgs>
 
     <_XHarnessArgs Condition="'$(Scenario)' != 'WasmTestOnBrowser'">$(_XHarnessArgs) --engine=$(JSEngine) $(JSEngineArgs) --js-file=runtime.js</_XHarnessArgs>
+    <_XHarnessArgs Condition="'$(BrowserHost)' == 'windows'">$(_XHarnessArgs) --browser=chrome --browser-path=%HELIX_CORRELATION_PAYLOAD%\chrome-win\chrome.exe</_XHarnessArgs>
     <_XHarnessArgs Condition="'$(IsFunctionalTest)' == 'true'"     >$(_XHarnessArgs) --expected-exit-code=$(ExpectedExitCode)</_XHarnessArgs>
     <_XHarnessArgs Condition="'$(WasmXHarnessArgs)' != ''"         >$(_XHarnessArgs) $(WasmXHarnessArgs)</_XHarnessArgs>
 
diff --git a/src/libraries/sendtohelixhelp.proj b/src/libraries/sendtohelixhelp.proj
index af2885bbecde6..08bdf4fdb0702 100644
--- a/src/libraries/sendtohelixhelp.proj
+++ b/src/libraries/sendtohelixhelp.proj
@@ -34,6 +34,7 @@
     <_workItemTimeout Condition="'$(Scenario)' == '' and '$(_workItemTimeout)' == '' and '$(Outerloop)' == 'true'">00:20:00</_workItemTimeout>
     <_workItemTimeout Condition="'$(Scenario)' == '' and '$(_workItemTimeout)' == ''">00:15:00</_workItemTimeout>
     <_workItemTimeout Condition="'$(Scenario)' != '' and '$(_workItemTimeout)' == ''">00:30:00</_workItemTimeout>
+    <_workItemTimeout Condition="'$(Scenario)' == 'wasmtestonbrowser' and '$(BrowserHost)' == 'windows'">00:45:00</_workItemTimeout>
 
     <!-- The Helix runtime payload and the tests to run -->
     <!-- TestArchiveRuntimeFile will be passed as a property by the calling project -->
@@ -110,6 +111,10 @@
     <HelixPreCommand Include="export PATH=$HELIX_CORRELATION_PAYLOAD/chromedriver_linux64:$PATH" />
     <HelixPreCommand Include="export PATH=$HELIX_CORRELATION_PAYLOAD/chrome-linux:$PATH" />
   </ItemGroup>
+  <ItemGroup Condition="'$(NeedsToRunOnBrowser)' == 'true' and '$(WindowsShell)' == 'true'">
+    <HelixPreCommand Include="set PATH=%HELIX_CORRELATION_PAYLOAD%\chromedriver_win32%3B%PATH%" />
+    <HelixPreCommand Include="set PATH=%HELIX_CORRELATION_PAYLOAD%\chrome-win%3B%PATH%" />
+  </ItemGroup>
 
   <Choose>
     <When Condition="'$(NeedsWorkload)' == 'true'">
@@ -308,11 +313,6 @@
     </ItemGroup>
 
     <PropertyGroup Condition="'$(TargetOS)' == 'Browser'">
-      <!-- Version number to revision number mapping from http://omahaproxy.appspot.com/ -->
-      <!-- 84.0.4147.105 is 768962 for example -->
-      <ChromiumRevision>768968</ChromiumRevision>
-      <ChromiumUrl>https://storage.googleapis.com/chromium-browser-snapshots/Linux_x64/$(ChromiumRevision)/chrome-linux.zip</ChromiumUrl>
-      <ChromeDriverUrl>https://storage.googleapis.com/chromium-browser-snapshots/Linux_x64/$(ChromiumRevision)/chromedriver_linux64.zip</ChromeDriverUrl>
       <EmSdkDir>$([MSBuild]::NormalizeDirectory('$(RepoRoot)', 'src', 'mono', 'wasm', 'emsdk'))</EmSdkDir>
       <WasmBuildTargetsDir>$([MSBuild]::NormalizeDirectory('$(RepoRoot)', 'src', 'mono', 'wasm', 'build'))</WasmBuildTargetsDir>
       <TestEchoMiddleware>$([MSBuild]::NormalizeDirectory('$(ArtifactsDir)', 'bin', 'NetCoreServer', '$(NetCoreAppCurrent)-$(Configuration)'))</TestEchoMiddleware>
@@ -320,6 +320,18 @@
       <WorkItemPrefix Condition="'$(Scenario)' == 'BuildWasmApps' and '$(TestUsingWorkloads)' == 'true'">Workloads-</WorkItemPrefix>
       <WorkItemPrefix Condition="'$(Scenario)' == 'BuildWasmApps' and '$(TestUsingWorkloads)' != 'true'">EMSDK-</WorkItemPrefix>
     </PropertyGroup>
+    <PropertyGroup Condition="'$(TargetOS)' == 'Browser' and '$(BrowserHost)' != 'windows'">
+      <!-- Version number to revision number mapping from http://omahaproxy.appspot.com/ -->
+      <!-- 84.0.4147.105 is 768962 for example -->
+      <ChromiumRevision>768968</ChromiumRevision>
+      <ChromiumUrl>https://storage.googleapis.com/chromium-browser-snapshots/Linux_x64/$(ChromiumRevision)/chrome-linux.zip</ChromiumUrl>
+      <ChromeDriverUrl>https://storage.googleapis.com/chromium-browser-snapshots/Linux_x64/$(ChromiumRevision)/chromedriver_linux64.zip</ChromeDriverUrl>
+    </PropertyGroup>
+    <PropertyGroup Condition="'$(TargetOS)' == 'Browser' and '$(BrowserHost)' == 'windows'">
+      <ChromiumRevision>768983</ChromiumRevision>
+      <ChromiumUrl>https://storage.googleapis.com/chromium-browser-snapshots/Win_x64/$(ChromiumRevision)/chrome-win.zip</ChromiumUrl>
+      <ChromeDriverUrl>https://storage.googleapis.com/chromium-browser-snapshots/Win_x64/$(ChromiumRevision)/chromedriver_win32.zip</ChromeDriverUrl>
+    </PropertyGroup>
 
     <PropertyGroup Condition="'$(RuntimeFlavor)' == 'Mono'">
       <_MonoAotCrossCompilerPath>$([MSBuild]::NormalizePath($(MonoAotCrossDir), 'mono-aot-cross'))</_MonoAotCrossCompilerPath>
@@ -369,8 +381,8 @@
       <HelixCorrelationPayload Include="$(HelixCorrelationPayload)"
                                Condition="'$(IncludeHelixCorrelationPayload)' == 'true' and '$(TargetOS)' != 'Browser'"
                                AsArchive="$(HelixCorrelationPayload.EndsWith('.zip'))" />
-      <HelixCorrelationPayload Include="chromium" Uri="$(ChromiumUrl)"         Condition="'$(NeedsToRunOnBrowser)' == 'true' and '$(BrowserHost)' != 'windows'" />
-      <HelixCorrelationPayload Include="chromedriver" Uri="$(ChromeDriverUrl)" Condition="'$(NeedsToRunOnBrowser)' == 'true' and '$(BrowserHost)' != 'windows'" />
+      <HelixCorrelationPayload Include="chromium" Uri="$(ChromiumUrl)"         Condition="'$(NeedsToRunOnBrowser)' == 'true'" />
+      <HelixCorrelationPayload Include="chromedriver" Uri="$(ChromeDriverUrl)" Condition="'$(NeedsToRunOnBrowser)' == 'true'" />
 
       <_WorkItem Include="$(WorkItemArchiveWildCard)" Exclude="$(HelixCorrelationPayload)" />
       <_WorkItem Include="$(TestArchiveRoot)runonly/**/WebAssembly.Console.*.Test.zip" Condition="'$(TargetOS)' == 'Browser' and '$(Scenario)' != 'WasmTestOnBrowser' and '$(Scenario)' != 'BuildWasmApps'" />
@@ -393,6 +405,7 @@
       <ExecXHarnessCmd>dotnet exec %XHARNESS_CLI_PATH%</ExecXHarnessCmd>
       <XHarnessOutput>%HELIX_WORKITEM_UPLOAD_ROOT%\xharness-output</XHarnessOutput>
       <XHarnessCommand>%XHARNESS_COMMAND%</XHarnessCommand>
+      <XHarnessBrowserPathArg>--browser-path=%HELIX_CORRELATION_PAYLOAD%\chrome-win\chrome.exe</XHarnessBrowserPathArg>
     </PropertyGroup>
 
     <ItemGroup Condition="'$(TargetOS)' == 'Browser' and '$(Scenario)' != 'WasmTestOnBrowser' and '$(Scenario)' != 'BuildWasmApps'">
@@ -411,7 +424,7 @@
       <HelixWorkItem Include="@(_RunOnlyWorkItem -> '%(FileName)')" >
         <PayloadArchive>%(Identity)</PayloadArchive>
         <!-- No RunTests script generated for the sample project so we just use the direct command -->
-        <Command>$(ExecXHarnessCmd) wasm $(XHarnessCommand)  --app=. --browser=Chrome  --html-file=index.html --output-directory=$(XHarnessOutput) -- %(FileName).dll --testing</Command>
+        <Command>$(ExecXHarnessCmd) wasm $(XHarnessCommand)  --app=. --browser=Chrome $(XHarnessBrowserPathArg) --html-file=index.html --output-directory=$(XHarnessOutput) -- %(FileName).dll --testing</Command>
       </HelixWorkItem>
     </ItemGroup>
 
diff --git a/src/libraries/tests.proj b/src/libraries/tests.proj
index fbc717a148846..7fa4235510fe7 100644
--- a/src/libraries/tests.proj
+++ b/src/libraries/tests.proj
@@ -321,6 +321,18 @@
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.IO.Compression.ZipFile\tests\System.IO.Compression.ZipFile.Tests.csproj" />
     <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Private.Xml\tests\Xslt\XslCompiledTransformApi\System.Xml.Xsl.XslCompiledTransformApi.Tests.csproj" />
     <ProjectExclusions Include="$(MonoProjectRoot)sample\wasm\console\Wasm.Console.Sample.csproj" />
+    <ProjectExclusions Include="$(MonoProjectRoot)sample\wasm\browser\Wasm.Browser.Sample.csproj" />
+  </ItemGroup>
+
+  <ItemGroup Condition="'$(TargetOS)' == 'Browser' and '$(BrowserHost)' == 'windows' and '$(Scenario)' == 'WasmTestOnBrowser' and '$(RunDisabledWasmTestsOnWindows)' != 'true'">
+    <!-- Issue: https://github.com/dotnet/runtime/issues/55429 -->
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)Microsoft.VisualBasic.Core\tests\Microsoft.VisualBasic.Core.Tests.csproj" />
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.IO\tests\System.IO.Tests.csproj" />
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Linq.Expressions\tests\System.Linq.Expressions.Tests.csproj" />
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Memory\tests\System.Memory.Tests.csproj" />
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Runtime.Tests.csproj" />
+    <ProjectExclusions Include="$(MSBuildThisFileDirectory)System.Private.Xml\tests\Writers\XmlWriterApi\System.Xml.RW.XmlWriterApi.Tests.csproj" />
+    <ProjectExclusions Include="$(RepoRoot)\src\tests\BuildWasmApps\Wasm.Build.Tests\Wasm.Build.Tests.csproj" />
   </ItemGroup>
 
   <ItemGroup Condition="'$(TargetOS)' == 'OSX' and '$(TargetArchitecture)' == 'arm64' and '$(RunDisabledAppleSiliconTests)' != 'true'">