diff --git a/eng/pipelines/runtime-official.yml b/eng/pipelines/runtime-official.yml
index 21b43cacf23ac..6029fb95f8d53 100644
--- a/eng/pipelines/runtime-official.yml
+++ b/eng/pipelines/runtime-official.yml
@@ -452,6 +452,7 @@ extends:
           runtimeFlavor: mono
           buildConfig: release
           platforms:
+          - windows_arm64
           - windows_x64
           jobParameters:
             buildArgs: -s mono+packs -c $(_BuildConfig)
@@ -633,6 +634,7 @@ extends:
             - Build_tvos_arm64_release_Mono
             - Build_tvossimulator_arm64_release_Mono
             - Build_tvossimulator_x64_release_Mono
+            - Build_windows_arm64_release_CrossAOT_Mono
             - Build_windows_x64_release_CrossAOT_Mono
             - Build_windows_x64_release_CoreCLR
             - Build_windows_x86_release_CoreCLR
diff --git a/eng/pipelines/runtime.yml b/eng/pipelines/runtime.yml
index 89bb17eed4ae7..82e221e429e29 100644
--- a/eng/pipelines/runtime.yml
+++ b/eng/pipelines/runtime.yml
@@ -924,9 +924,8 @@ extends:
           - linux_musl_x64
           - linux_arm64
           - linux_musl_arm64
+          - windows_arm64
           - windows_x64
-          # - windows_x86
-          # - windows_arm64
           jobParameters:
             runtimeVariant: crossaot
             dependsOn:
diff --git a/src/mono/CMakeLists.txt b/src/mono/CMakeLists.txt
index 62220db825721..4bf280134c0d6 100644
--- a/src/mono/CMakeLists.txt
+++ b/src/mono/CMakeLists.txt
@@ -280,6 +280,7 @@ elseif(CLR_CMAKE_HOST_OS STREQUAL "windows")
   set(CMAKE_MSVC_RUNTIME_LIBRARY "MultiThreaded$<$<CONFIG:Debug>:Debug>") # statically link VC runtime library
   add_compile_options(/W4)   # set warning level 4
   add_compile_options($<$<COMPILE_LANGUAGE:C,CXX>:/WX>) # treat warnings as errors
+  add_compile_options($<$<COMPILE_LANGUAGE:C,CXX>:/wd4324>) # 'struct_name' : structure was padded due to __declspec(align())
   add_compile_options(/EHsc) # set exception handling behavior
   add_compile_options(/FC)   # use full pathnames in diagnostics
   add_link_options(/STACK:0x800000)  # set stack size to 8MB (default is 1MB)
diff --git a/src/mono/mono.proj b/src/mono/mono.proj
index 4b217174fca76..78ea1292e48e2 100644
--- a/src/mono/mono.proj
+++ b/src/mono/mono.proj
@@ -360,6 +360,7 @@
       <_MonoCPPFLAGS Include="-DWIN32_LEAN_AND_MEAN" />
       <!--<_MonoCPPFLAGS Include="-D_WINDOWS" />--> <!-- set in monow.vcxproj, not sure we really need it -->
       <_MonoCPPFLAGS Condition="'$(Platform)' == 'x64' or '$(Platform)' == 'arm64'" Include="-DWIN64" />
+      <_MonoCPPFLAGS Condition="'$(Platform)' == 'arm64'" Include="-DUSE_SOFT_INTRINSICS" />
       <_MonoCPPFLAGS Condition="'$(Configuration)' == 'Release'" Include="-DNDEBUG" />
       <_MonoCPPFLAGS Condition="'$(Configuration)' == 'Debug'" Include="-D_DEBUG" />
       <!-- <_MonoCPPFLAGS Include="-D__default_codegen__" /> --> <!-- doesn't seem to be used -->
@@ -749,6 +750,7 @@
       <_MonoAOTCPPFLAGS Include="-DWIN32_LEAN_AND_MEAN" />
       <!--<_MonoAOTCPPFLAGS Include="-D_WINDOWS" />--> <!-- set in monow.vcxproj, not sure we really need it -->
       <_MonoAOTCPPFLAGS Condition="'$(Platform)' == 'x64' or '$(Platform)' == 'arm64'" Include="-DWIN64" />
+      <_MonoAOTCPPFLAGS Condition="'$(AotHostArchitecture)' == 'arm64'" Include="-DUSE_SOFT_INTRINSICS" />
       <_MonoAOTCPPFLAGS Condition="'$(Configuration)' == 'Release' or '$(_ForceRelease)' == 'true'" Include="-DNDEBUG" />
       <_MonoAOTCPPFLAGS Condition="'$(Configuration)' == 'Debug' and '$(_ForceRelease)' != 'true'" Include="-D_DEBUG" />
       <!-- <_MonoAOTCPPFLAGS Include="-D__default_codegen__" /> --> <!-- doesn't seem to be used -->
diff --git a/src/mono/mono/mini/exceptions-amd64.c b/src/mono/mono/mini/exceptions-amd64.c
index 0a0121a76a7dc..20ba681ab5265 100644
--- a/src/mono/mono/mini/exceptions-amd64.c
+++ b/src/mono/mono/mini/exceptions-amd64.c
@@ -838,7 +838,11 @@ mono_arch_ip_from_context (void *sigctx)
 #if defined(MONO_ARCH_USE_SIGACTION)
 	return (gpointer)UCONTEXT_REG_RIP ((ucontext_t*)sigctx);
 #elif defined(HOST_WIN32)
+#if defined(MONO_CROSS_COMPILE)
+	return (gpointer)NULL;
+#else
 	return (gpointer)(((CONTEXT*)sigctx)->Rip);
+#endif
 #else
 	MonoContext *ctx = (MonoContext*)sigctx;
 	return (gpointer)ctx->gregs [AMD64_RIP];
diff --git a/src/mono/mono/utils/mach-support-arm64.c b/src/mono/mono/utils/mach-support-arm64.c
index 97391f9bdb525..6ddd5a8911dab 100644
--- a/src/mono/mono/utils/mach-support-arm64.c
+++ b/src/mono/mono/utils/mach-support-arm64.c
@@ -128,4 +128,10 @@ mono_mach_arch_set_thread_states (thread_port_t thread, thread_state_t state, ma
 #endif
 }
 
+#else
+
+#include <mono/utils/mono-compiler.h>
+
+MONO_EMPTY_SOURCE_FILE (mach_support_arm64);
+
 #endif
diff --git a/src/mono/mono/utils/mono-context.h b/src/mono/mono/utils/mono-context.h
index 0e5117c0b9ef0..686ec7c038ff4 100644
--- a/src/mono/mono/utils/mono-context.h
+++ b/src/mono/mono/utils/mono-context.h
@@ -56,6 +56,7 @@ typedef __uint128_t MonoContextSimdReg;
 #elif defined(HOST_WIN32)
 #define MONO_HAVE_SIMD_REG
 //#define MONO_HAVE_SIMD_REG_AVX
+#include <intrin.h>
 #include <emmintrin.h>
 typedef __m128d MonoContextSimdReg;
 #elif defined(HOST_ANDROID)
@@ -77,6 +78,7 @@ typedef __uint128_t MonoContextSimdReg;
    a stand-in. This is not expected to work for Windows ARM64 native builds. */
 #if defined(HOST_WIN32)
 #define MONO_HAVE_SIMD_REG
+#include <intrin.h>
 #include <emmintrin.h>
 typedef __m128d MonoContextSimdReg;
 #else
@@ -507,7 +509,7 @@ typedef struct {
 
 #define MONO_ARCH_HAS_MONO_CONTEXT 1
 
-#elif (defined(__aarch64__) && !defined(MONO_CROSS_COMPILE)) || (defined(TARGET_ARM64))
+#elif ((defined(_M_ARM64) || defined(__aarch64__)) && !defined(MONO_CROSS_COMPILE)) || (defined(TARGET_ARM64))
 
 #include <mono/arch/arm64/arm64-codegen.h>
 
diff --git a/src/mono/mono/utils/mono-threads-coop.c b/src/mono/mono/utils/mono-threads-coop.c
index 4f3ea537cdd60..f96285876b30f 100644
--- a/src/mono/mono/utils/mono-threads-coop.c
+++ b/src/mono/mono/utils/mono-threads-coop.c
@@ -198,7 +198,8 @@ copy_stack_data_internal (MonoThreadInfo *info, MonoStackData *stackdata_begin,
 #ifdef _MSC_VER
 typedef void (*CopyStackDataFunc)(MonoThreadInfo *, MonoStackData *, gconstpointer, gconstpointer);
 
-#ifdef HOST_AMD64
+#if defined(HOST_AMD64) || defined(HOST_ARM64)
+#include <intrin.h>
 #include <emmintrin.h>
 // Implementation of __builtin_unwind_init under MSVC, dumping nonvolatile registers into MonoBuiltinUnwindInfo.
 typedef struct {
@@ -206,9 +207,11 @@ typedef struct {
 	host_mgreg_t gregs [8];
 } MonoBuiltinUnwindInfo;
 
+#if defined(HOST_AMD64)
 // Defined in win64.asm
 G_EXTERN_C void
 copy_stack_data_internal_win32_wrapper (MonoThreadInfo *, MonoStackData *, MonoBuiltinUnwindInfo *, CopyStackDataFunc);
+#endif
 #else
 // Implementation of __builtin_unwind_init under MSVC, dumping nonvolatile registers into MonoBuiltinUnwindInfo.
 typedef struct {
@@ -238,8 +241,10 @@ copy_stack_data_internal_win32_wrapper (MonoThreadInfo *info, MonoStackData *sta
 static void
 copy_stack_data (MonoThreadInfo *info, MonoStackData *stackdata_begin)
 {
+#if defined(HOST_AMD64)
 	MonoBuiltinUnwindInfo unwind_info_data;
 	copy_stack_data_internal_win32_wrapper (info, stackdata_begin, &unwind_info_data, copy_stack_data_internal);
+#endif
 }
 #else
 static void
diff --git a/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Current.Manifest/WorkloadManifest.json.in b/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Current.Manifest/WorkloadManifest.json.in
index 25ac8ef1c8e48..9dc1c0c92d29b 100644
--- a/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Current.Manifest/WorkloadManifest.json.in
+++ b/src/mono/nuget/Microsoft.NET.Workload.Mono.Toolchain.Current.Manifest/WorkloadManifest.json.in
@@ -205,7 +205,7 @@
       "version": "${PackageVersion}",
       "alias-to": {
         "win-x64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-x86",
-        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-x86",
+        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-arm64.Cross.android-x86",
         "linux-x64": "Microsoft.NETCore.App.Runtime.AOT.linux-x64.Cross.android-x86",
         "linux-arm64": "Microsoft.NETCore.App.Runtime.AOT.linux-arm64.Cross.android-x86",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.android-x86",
@@ -217,7 +217,7 @@
       "version": "${PackageVersion}",
       "alias-to": {
         "win-x64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-x64",
-        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-x64",
+        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-arm64.Cross.android-x64",
         "linux-x64": "Microsoft.NETCore.App.Runtime.AOT.linux-x64.Cross.android-x64",
         "linux-arm64": "Microsoft.NETCore.App.Runtime.AOT.linux-arm64.Cross.android-x64",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.android-x64",
@@ -229,7 +229,7 @@
       "version": "${PackageVersion}",
       "alias-to": {
         "win-x64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-arm",
-        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-arm",
+        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-arm64.Cross.android-arm",
         "linux-x64": "Microsoft.NETCore.App.Runtime.AOT.linux-x64.Cross.android-arm",
         "linux-arm64": "Microsoft.NETCore.App.Runtime.AOT.linux-arm64.Cross.android-arm",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.android-arm",
@@ -241,7 +241,7 @@
       "version": "${PackageVersion}",
       "alias-to": {
         "win-x64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-arm64",
-        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.android-arm64",
+        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-arm64.Cross.android-arm64",
         "linux-x64": "Microsoft.NETCore.App.Runtime.AOT.linux-x64.Cross.android-arm64",
         "linux-arm64": "Microsoft.NETCore.App.Runtime.AOT.linux-arm64.Cross.android-arm64",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.android-arm64",
@@ -365,7 +365,7 @@
       "version": "${PackageVersion}",
       "alias-to": {
         "win-x64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.browser-wasm",
-        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-x64.Cross.browser-wasm",
+        "win-arm64": "Microsoft.NETCore.App.Runtime.AOT.win-arm64.Cross.browser-wasm",
         "linux-x64": "Microsoft.NETCore.App.Runtime.AOT.linux-x64.Cross.browser-wasm",
         "linux-arm64": "Microsoft.NETCore.App.Runtime.AOT.linux-arm64.Cross.browser-wasm",
         "osx-x64": "Microsoft.NETCore.App.Runtime.AOT.osx-x64.Cross.browser-wasm",