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README.md

Welcome to the Latent Strain Analysis (LSA) code repository!

LSA was developed as a pre-assembly tool for partitioning metagenomic reads. It uses a hyperplane hashing function and streaming SVD in order to find covariance relations between k-mers. The code, and the process outline in LSFScripts in particular, have been optimized to scale to massive data sets in fixed memory with a highly distributed computing environment.

Documentation

Documentation for LSA, including a "getting started" tutorial with accompanying test data, and step-by-step instructions for analyzing large collections, can be found at: http://latentstrainanalysis.readthedocs.org/

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Partitioning and analysis methods for large, complex sequence datasets

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