diff --git a/easybuild/easyconfigs/t/TRUST4/TRUST4-1.0.5.1.eb b/easybuild/easyconfigs/t/TRUST4/TRUST4-1.0.5.1.eb
new file mode 100644
index 000000000000..23e4ab181ac5
--- /dev/null
+++ b/easybuild/easyconfigs/t/TRUST4/TRUST4-1.0.5.1.eb
@@ -0,0 +1,26 @@
+easyblock = 'Conda'
+
+name = "TRUST4"
+version = "1.0.5.1"
+
+homepage = 'https://github.com/liulab-dfci/TRUST4'
+description = """Tcr Receptor Utilities for Solid Tissue (TRUST) is a computational tool to 
+analyze TCR and BCR sequences using unselected RNA sequencing data, profiled 
+from solid tissues, including tumors. TRUST4 performs de novo assembly on V, J, 
+C genes including the hypervariable complementarity-determining region 3 (CDR3) 
+and reports consensus of BCR/TCR sequences."""
+
+toolchain = SYSTEM
+
+requirements = "%(namelower)s=%(version)s"
+channels = ['bioconda']
+
+builddependencies = [('Miniconda3', '4.9.2')]
+
+sanity_check_paths = {
+    'files': ['bin/%s' % x for x in ['trust4', 'run-trust4', 'bam-extractor',
+                                     'fastq-extractor']],
+    'dirs': ['bin', 'conda-meta', 'lib']
+}
+
+moduleclass = 'bio'