Data extraction and front-end code for EU Trials Tracker
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README.md

euctr-tracker

How it works

Code and data layout

There are two repos which should be checked out in a common directory. One is euctr-tracker-code, and the other is euctr-tracker-data.

The latter contains JSON files which are loaded into memory by the frontend Django app in euctr-tracker-code loads the contents of the JSON files into memory.

Thus we avoid using a database. Originally this design made sense as the data structure was simple, and the source data was in a third party database over which we had no control. This makes less sense now as we run our own database for the source data, and the model has become more complex; we do, however, maintain the advantage of maintaining all the historic data in git.

Service operation

Once a month, we run a shell script crawl-and-dump-eutrialstracker_live.sh that does two things:

  1. It executes command that uses scrapy to scrape the EUCTR register, via cron. This writes to a local postgres database, euctr. It takes up to 4 days to run - it must do a full scrape each time, due to the design of the website we are scraping.
  2. It runs the Djano management command get_trials_from_db, which creates a CSV based on this data, and writes it to the euctr-tracker-data directory.

Every 30 minutes, loaddata-eutrialstracker_live.sh is also run. If any uncommitted changes are found in the euctr-tracker-data directory, it executes the django management command update_trials_json, to create the set of JSON files which drive the website.

However, this second shell script will often (deliberately) exit early, because the sponsors CSV file (see Terminology section, below) contains rows that have not had the normalised sponsor column updated. This will happen every time new sponsors are added. When the update_trials_json script exits early, it emails a recipient specified in the django settings file, telling them intervention is needed.

The recipient should edit the CSV and update it directly in the euctr-tracker-data repo; loaddata-eutrialstracker_live.sh will then pick this up on the next run. Finally, this script will commit all the latest generated files to the euctr-tracker-data repostory.

Development

Install these Python development packages before you begin. For example, on a Debian-based system:

apt install python3 python3-venv build-essential python3-dev phantomjs

Using Python 3, create and enter a virtualenv, as described here. For example:

python3.5 -m venv venv
. venv/bin/activate

Install required Python packages.

pip install -r requirements.txt

Set environment variables required.

export EUCTR_SECRET_KEY= # random longish string for sessions
export EUCTR_DEBUG= # yes or no
export EUCTR_OPENTRIALS_DB=postgres://<account_name>:<password>@<servername>/warehouse

export EUCTR_GOOGLE_TRACKING_ID= # optional Analytics id, e.g. UA-nnnnnnnn-n
export EUCTR_CRAWLERA_APIKEY= # for crawler proxying

Checkout the data respository.

cd ..
git clone git@github.com:ebmdatalab/euctr-tracker-data.git
cd -

Run the application.

cd euctr
./manage.py runserver

There are a few tests.

./manage.py test

Deployment

We use fabric to deploy over SSH to a pet server.

fab deploy:live

The code and data are updated via git from the master branch of their repositories.

The configuration is in fabfile.py and the deploy directory.

When settings up a new server:

  • Put environment settings live in /etc/profile.d/eutrialstracker_live.sh
  • Put SSH keys for the git repositories in /var/www/eutrialstracker_live/ssh-keys

Loading new data

The frontend application reads data from static JSON files in the ../euctr-tracker-data/ directory.

  1. Set the location of a PostgreSQL database. This is only used as an intermediate store for the crawler to keep data in. The live website doesn't use it.
export EUCTR\_OPENTRIALS\_DB=postgres://username:password@hostname/dbname

If you need the schema, look in euctr/crawl/schema.sql.

  1. Run the EUCTR crawler to populate the PostgreSQL database by running with a date range:
cd euctr
./manage.py run_crawler 2004-01-01 2017-09-19

Or update results from a particular query, e.g. a specific trial id:

./manage.py run_crawler --query=2004-000012-13
  1. Update ../euctr-tracker-data/trials.csv from the PostgreSQL database by running:
./manage.py get_trials_from_db

This assumes the table is called "euctr". It uses the SQL script opentrials-to-csv.sql for the calculations and conversions needed.

  1. Regenerate the JSON files from the CSV file by running:
./manage.py update_trials_json

Terminology

The spreadsheet ../euctr-tracker-data/normalized_sponsor_names.xlsx contains normalized versions of the names for trials that are listed in the register.

normalized_name_only: This column represents normalization based only on sponsor name or very simple research. Different spelling/abbreviations of a sponsor name and divisions/subsidiaries of the same sponsor will be normalized to the same parent sponsor name (ex: DrugCompany Inc., DrugCompany Incorporated and DrugCompany Generics would all be normalized to the generic DrugCompany Inc.). This also includes, where possible, instances in which a sponsor name is implemented in different languages and also attempts to consolidate hospital systems under a single normalized name (ex: Putting hospitals in the Copenhagen University hospital system together or matching an old NHS Trust name to the new name). If a sponsor is identified in their sponsor name as part of another company (ex: “doing business as” or “a wholly owned subsidiary of” ) then that company will be normalized to the parent company identified (ex: “GenericCompany Inc, a wholly owned subsidiary of Drugs Inc.” would normalize to “Drugs Inc.“). Attempts are also made to make sponsor names more uniform and readable with the removal of extraneous text or names in all capital letters.

normalized_name: This column represents an effort to normalize based on more in depth research into mergers, acquisitions and name changes for corporate entities. Proof is sought to account changes in corporate ownership and where it is believed responsibility for reporting would ultimately be vested. Proof of notable acquisitions is given in the spreadsheet for changes made in this column.