diff --git a/test/TestConfig/resources/excludes/latest_exclude_19.txt b/test/TestConfig/resources/excludes/latest_exclude_19.txt
index af7a0bd43da..2f60bec9fec 100644
--- a/test/TestConfig/resources/excludes/latest_exclude_19.txt
+++ b/test/TestConfig/resources/excludes/latest_exclude_19.txt
@@ -1,5 +1,5 @@
 ##############################################################################
-# Copyright (c) 2021, 2021 IBM Corp. and others
+# Copyright (c) 2021, 2022 IBM Corp. and others
 #
 # This program and the accompanying materials are made available under
 # the terms of the Eclipse Public License 2.0 which accompanies this
@@ -30,3 +30,22 @@ org.openj9.test.nestmates.NestAttributeTest:testGetNestMembersAPIInValidHostWron
 org.openj9.test.nestmates.NestAttributeTest:testGetNestMembersAPINestMemberWrongPackage NA generic-all
 org.openj9.test.nestmates.NestAttributeTest:testGetNestMembersAPINestMemberWrongNestHost NA generic-all
 org.openj9.test.nestmates.NestAttributeTest:testGetNestMembersAPINestMemberWrongNestHost2 NA generic-all
+
+# Exclude Java 19 Thread related failures
+
+org.openj9.test.java.lang.Test_ThreadGroup:test_activeCount NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_Constructor2 NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_destroy NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_destroy2 NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_destroy3 NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_list NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_remove NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_resume NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_setDaemon2 NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_stop NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_suspend NA generic-all
+org.openj9.test.java.lang.Test_ThreadGroup:test_uncaughtException NA generic-all
+org.openj9.test.java.lang.Test_Thread:test_start_WeakReference NA generic-all
+org.openj9.test.java.lang.Test_Thread:test_currentThread NA generic-all
+org.openj9.test.java.lang.Test_Thread:test_toString NA generic-all
+org.openj9.test.java.lang.management.TestManagementFactory:testGetPlatformMXBeans NA generic-all
diff --git a/test/functional/JIT_Test/playlist.xml b/test/functional/JIT_Test/playlist.xml
index 324fb704918..dafd2fa9d90 100644
--- a/test/functional/JIT_Test/playlist.xml
+++ b/test/functional/JIT_Test/playlist.xml
@@ -204,6 +204,12 @@
 	</test>
 	<test>
 		<testCaseName>jit_jitt_openj9_none_SCC</testCaseName>
+		<disables>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+			</disable>
+		</disables>
 		<variations>
 			<variation>-Xjit:noJitUntilMain,count=0,optlevel=warm,gcOnResolve,rtResolve -verbose:stackwalk=0 -Xdump</variation>
 			<variation>-Xrs -Xjit:noJitUntilMain,count=0,optlevel=warm,gcOnResolve,rtResolve -verbose:stackwalk=0 -Xdump</variation>
diff --git a/test/functional/JavaAgentTest/playlist.xml b/test/functional/JavaAgentTest/playlist.xml
index 4a47dc0349e..bb8e2d2f25b 100644
--- a/test/functional/JavaAgentTest/playlist.xml
+++ b/test/functional/JavaAgentTest/playlist.xml
@@ -23,6 +23,13 @@
 <playlist xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="../../TKG/playlist.xsd">
 	<test>
 		<testCaseName>TestFlushReflectionCache</testCaseName>
+		<disables>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode107</variation>
+			</disable>
+		</disables>
 		<variations>
 			<variation>NoOptions</variation>
 			<variation>Mode100</variation>
diff --git a/test/functional/cmdLineTests/gcRegressionTests/gcRegressionTests_excludes.xml b/test/functional/cmdLineTests/gcRegressionTests/gcRegressionTests_excludes.xml
index 5649bbb79b6..9e7a4914530 100644
--- a/test/functional/cmdLineTests/gcRegressionTests/gcRegressionTests_excludes.xml
+++ b/test/functional/cmdLineTests/gcRegressionTests/gcRegressionTests_excludes.xml
@@ -27,11 +27,15 @@
 
 <suite id="J9 GC Regression Tests">
 
+<!-- Java 19 Porject Loom excluded tests -->
+<exclude id="-verbose:gc -Xcheck:memory - check for memory corruption" platform="19" shouldFix="true"><reason>Temp disable on Loom test failures</reason></exclude>
+<exclude id="-verbose:gc -Xcheck:memory -Xverbosegclog:foo.log - check for memory corruption" platform="19" shouldFix="true"><reason>Temp disable on Loom test failures</reason></exclude>
+
 <!-- Hard RTJ doesn't support dynamic class unloading, SRT: out of memory issues  -->
-<exclude id="Unload lots of classes using normal behaviour (JIT Disabled)" platform="Mode301" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
-<exclude id="Unload lots of classes using FVT stress argument to force finalization (JIT Disabled)" platform="Mode301" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
-<exclude id="Unload lots of classes using normal behaviour (with JIT if JIT is Enabled)" platform="Mode301" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
-<exclude id="Unload lots of classes using FVT stress argument to force finalization (with JIT if JIT is Enabled)" platform="Mode301" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
+<exclude id="Unload lots of classes using normal behaviour (JIT Disabled)" platform="Mode301 19" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
+<exclude id="Unload lots of classes using FVT stress argument to force finalization (JIT Disabled)" platform="Mode301 19" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
+<exclude id="Unload lots of classes using normal behaviour (with JIT if JIT is Enabled)" platform="Mode301 19" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
+<exclude id="Unload lots of classes using FVT stress argument to force finalization (with JIT if JIT is Enabled)" platform="Mode301 19" shouldFix="true"><reason>Class unloading not supported on RTJ</reason></exclude>
 
 <!-- Metronome and Staccato do not support contraction -->
 <exclude id="Run with arguments which will make contraction very unlikely" platform="Mode301" shouldFix="true"><reason>Metronome and Staccato do not support contraction</reason></exclude>
diff --git a/test/functional/cmdLineTests/gcRegressionTests/playlist.xml b/test/functional/cmdLineTests/gcRegressionTests/playlist.xml
index 9725f560626..fe0fd4eb0f5 100644
--- a/test/functional/cmdLineTests/gcRegressionTests/playlist.xml
+++ b/test/functional/cmdLineTests/gcRegressionTests/playlist.xml
@@ -31,7 +31,7 @@
 		</variations>
 		<command>$(JAVA_COMMAND) $(JVM_OPTIONS) -DTESTSJARPATH=$(Q)$(TEST_RESROOT)$(D)gcRegressionTests.jar$(Q) -DRESJAR=$(CMDLINETESTER_RESJAR) \
 		-DEXE=$(SQ)$(JAVA_COMMAND) $(JVM_OPTIONS)$(SQ) -jar $(CMDLINETESTER_JAR) -config $(Q)$(TEST_RESROOT)$(D)gcRegressionTests.xml$(Q) \
-		-explainExcludes -xids all,$(PLATFORM),$(VARIATION) -plats all,$(PLATFORM),$(VARIATION) -xlist $(Q)$(TEST_RESROOT)$(D)gcRegressionTests_excludes.xml$(Q) -nonZeroExitWhenError; \
+		-explainExcludes -xids all,$(PLATFORM),$(VARIATION),$(JDK_VERSION) -plats all,$(PLATFORM),$(VARIATION) -xlist $(Q)$(TEST_RESROOT)$(D)gcRegressionTests_excludes.xml$(Q) -nonZeroExitWhenError; \
 		$(TEST_STATUS)</command>
 		<levels>
 			<level>sanity</level>
@@ -95,7 +95,7 @@
 		</variations>
 		<command>$(JAVA_COMMAND) $(JVM_OPTIONS) -DTESTSJARPATH=$(Q)$(TEST_RESROOT)$(D)gcRegressionTests.jar$(Q) -DRESJAR=$(CMDLINETESTER_RESJAR) \
 		-DEXE=$(SQ)$(JAVA_COMMAND) $(JVM_OPTIONS)$(SQ) -jar $(CMDLINETESTER_JAR) -config $(Q)$(TEST_RESROOT)$(D)gcRegressionTests.xml$(Q) \
-		-explainExcludes -xids all,$(PLATFORM),Mode301 -plats all,$(PLATFORM),Mode301 -xlist $(Q)$(TEST_RESROOT)$(D)gcRegressionTests_excludes.xml$(Q) -explainExcludes -nonZeroExitWhenError; \
+		-explainExcludes -xids all,$(PLATFORM),Mode301,$(JDK_VERSION) -plats all,$(PLATFORM),Mode301 -xlist $(Q)$(TEST_RESROOT)$(D)gcRegressionTests_excludes.xml$(Q) -explainExcludes -nonZeroExitWhenError; \
 		$(TEST_STATUS)</command>
 		<levels>
 			<level>sanity</level>
diff --git a/test/functional/cmdLineTests/jvmtitests/jvmtitests_excludes_19.xml b/test/functional/cmdLineTests/jvmtitests/jvmtitests_excludes_19.xml
index 6775a2a3023..11c17ae6e9f 100644
--- a/test/functional/cmdLineTests/jvmtitests/jvmtitests_excludes_19.xml
+++ b/test/functional/cmdLineTests/jvmtitests/jvmtitests_excludes_19.xml
@@ -1,6 +1,6 @@
 <?xml version="1.0" encoding="UTF-8" standalone="no" ?>
 <!--
-Copyright (c) 2021, 2021 IBM Corp. and others
+Copyright (c) 2021, 2022 IBM Corp. and others
 
 This program and the accompanying materials are made available under
 the terms of the Eclipse Public License 2.0 which accompanies this
@@ -56,4 +56,8 @@ SPDX-License-Identifier: EPL-2.0 OR Apache-2.0 OR GPL-2.0 WITH Classpath-excepti
 		<reason>Nestmates are not enabled on java10</reason>
 	</exclude>
 
+	<exclude id="gtgc001" platform="all">
+		<reason>GetThreadGroupChildren requires refactor for Project Loom</reason>
+	</exclude>
+
 </suite>
diff --git a/test/functional/cmdLineTests/jvmtitests/playlist.xml b/test/functional/cmdLineTests/jvmtitests/playlist.xml
index 707101ca64a..dcddc58dc2b 100644
--- a/test/functional/cmdLineTests/jvmtitests/playlist.xml
+++ b/test/functional/cmdLineTests/jvmtitests/playlist.xml
@@ -193,6 +193,63 @@
 	</test>
 	<test>
 		<testCaseName>cmdLineTester_jvmtitests_debug</testCaseName>
+		<disables>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode107</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode108</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode154</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode307</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode357</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode507</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode557</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode607</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode608</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode107-OSR</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode607-OSR</variation>
+			</disable>
+		</disables>
 		<variations>
 			<variation>Mode100</variation>
 			<variation>Mode107</variation>
@@ -233,6 +290,63 @@
 	</test>
 	<test>
 		<testCaseName>cmdLineTester_jvmtitests_debug_openj9_none_SCC</testCaseName>
+		<disables>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode107</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode108</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode154</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode307</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode357</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode507</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode557</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode607</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode608</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode107-OSR</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode607-OSR</variation>
+			</disable>
+		</disables>
 		<variations>
 			<variation>Mode100</variation>
 			<variation>Mode107</variation>
@@ -618,6 +732,12 @@
 	</test>
 	<test>
 		<testCaseName>decompileAtMethodResolve</testCaseName>
+		<disables>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+			</disable>
+		</disables>
 		<variations>
 			<variation>NoOptions</variation>
 		</variations>
diff --git a/test/functional/cmdLineTests/jython/playlist.xml b/test/functional/cmdLineTests/jython/playlist.xml
index e9f86f34194..a43b5ac42e0 100644
--- a/test/functional/cmdLineTests/jython/playlist.xml
+++ b/test/functional/cmdLineTests/jython/playlist.xml
@@ -1,6 +1,6 @@
 <?xml version='1.0' encoding='UTF-8'?>
 <!--
-  Copyright (c) 2021, 2021 IBM Corp. and others
+  Copyright (c) 2021, 2022 IBM Corp. and others
 
   This program and the accompanying materials are made available under
   the terms of the Eclipse Public License 2.0 which accompanies this
@@ -30,6 +30,26 @@
 				<version>8</version>
 				<impl>ibm</impl>
 			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode108</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode116</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode608</variation>
+			</disable>
+			<disable>
+				<comment>https://github.com/eclipse-openj9/openj9/issues/15152</comment>
+				<version>19+</version>
+				<variation>Mode616</variation>
+			</disable>
 		</disables>
 		<variations>
 			<variation>NoOptions</variation>