diff --git a/EDAM_dev.owl b/EDAM_dev.owl
index a5b0084..ef72650 100644
--- a/EDAM_dev.owl
+++ b/EDAM_dev.owl
@@ -125,6 +125,7 @@
         <rdfs:label>File extension</rdfs:label>
         <oboInOwl:hasDefinition>&apos;File extension&apos; concept property (&apos;file_extension&apos; metadata tag) lists examples of usual file extensions of formats.</oboInOwl:hasDefinition>
         <rdfs:comment>Separated by bar (&apos;|&apos;), without a dot (&apos;.&apos;) prefix, preferrably not all capital characters.</rdfs:comment>
+        <rdfs:comment>N.B.: File extensions that are not correspondigly defined at http://filext.com are recorded in EDAM only if not in conflict with http://filext.com, and/or unique and usual within life-science computing.</rdfs:comment>
         <oboInOwl:inSubset>concept_properties</oboInOwl:inSubset>
         <oboOther:is_metadata_tag>true</oboOther:is_metadata_tag>
     </owl:AnnotationProperty>
@@ -135,7 +136,7 @@
 
     <owl:AnnotationProperty rdf:about="http://edamontology.org/isdebtag">
         <rdfs:label>isdebtag</rdfs:label>
-        <oboInOwl:hasDefinition>When &apos;true&apos;, the term has been proposed or is supported within Debian Med as a tag.</oboInOwl:hasDefinition>
+        <oboInOwl:hasDefinition>When &apos;true&apos;, the concept has been proposed or is supported within Debian as a tag.</oboInOwl:hasDefinition>
         <oboInOwl:inSubset>concept_properties</oboInOwl:inSubset>
         <oboOther:is_metadata_tag>true</oboOther:is_metadata_tag>
     </owl:AnnotationProperty>
@@ -154,9 +155,9 @@
     
 
 
-    <!-- http://edamontology.org/noClue -->
+    <!-- http://edamontology.org/comment_handle -->
 
-    <owl:AnnotationProperty rdf:about="http://edamontology.org/noClue"/>
+    <owl:AnnotationProperty rdf:about="http://edamontology.org/comment_handle"/>
     
 
 
@@ -33267,9 +33268,9 @@ experiments employing a combination of technologies.</oboInOwl:hasDefinition>
         <oboInOwl:hasExactSynonym>YAML Ain&apos;t Markup Language</oboInOwl:hasExactSynonym>
         <oboInOwl:hasDefinition>YAML (YAML Ain&apos;t Markup Language) is a human-readable tree-structured data serialisation language.</oboInOwl:hasDefinition>
         <file_extension>yaml|yml</file_extension>
-        <documentation rdf:resource="http://yaml.org"/>
         <oboInOwl:hasDbXref rdf:resource="http://filext.com/file-extension/YML"/>
-        <oboInOwl:inSubset rdf:resource="&oboOther;edam#edam"/>
+        <documentation rdf:resource="http://yaml.org"/>
+        <oboInOwl:inSubset rdf:resource="&oboOther;edam#edam"/> 
         <oboInOwl:inSubset rdf:resource="&oboOther;edam#formats"/>
         <oboInOwl:hasDbXref rdf:resource="https://en.wikipedia.org/wiki/YAML"/>
     </owl:Class>
@@ -44840,14 +44841,14 @@ Trim sequences (typically from an automated DNA sequencer) to remove sequence-sp
         <oboInOwl:hasExactSynonym>Format recognition</oboInOwl:hasExactSynonym>
         <rdfs:comment>&apos;Format recognition&apos; is not a bioinformatics-specific operation, but of great relevance in bioinformatics. Should be removed from EDAM if/when captured satisfactorily in a suitable domain-generic ontology.</rdfs:comment>
         <oboInOwl:hasExactSynonym>Format inference</oboInOwl:hasExactSynonym>
-        <noClue rdf:resource="http://edamontology.org/noClue"/>
+        <comment_handle rdf:resource="http://edamontology.org/comment_handle"/>
         <oboInOwl:inSubset rdf:resource="&oboOther;edam#edam"/>
         <oboInOwl:inSubset rdf:resource="&oboOther;edam#operations"/>
     </owl:Class>
     <owl:Axiom>
         <rdfs:comment>The has_input &quot;Data&quot; (data_0006) may cause visualisation or other problems although ontologically correct. But on the other hand it may be useful to distinguish from nullary operations without inputs.</rdfs:comment>
-        <owl:annotatedProperty rdf:resource="http://edamontology.org/noClue"/>
-        <owl:annotatedTarget rdf:resource="http://edamontology.org/noClue"/>
+        <owl:annotatedProperty rdf:resource="http://edamontology.org/comment_handle"/>
+        <owl:annotatedTarget rdf:resource="http://edamontology.org/comment_handle"/>
         <owl:annotatedSource rdf:resource="http://edamontology.org/operation_3357"/>
     </owl:Axiom>