Simple mathematical model of bidirectional active transport in axons (written in Mathematica).
General assuptions are:
- axonal microtubules are unidirectional (plus ends to periphery/growth cone)
- there are different ratios of kinesins/dyneins per single cargo
It corresponds to equations described in the publication:
LF Gumy, EA Katrukha, LC Kapitein, CC Hoogenraad New insights into mRNA trafficking in axons Developmental neurobiology, 2014